Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 150 (13 Feb 2019)
Sequence version 1 (01 Feb 1997)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

NEDD4-binding protein 2-like 2

Gene

N4BP2L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NEDD4-binding protein 2-like 2
Alternative name(s):
Phosphonoformate immuno-associated protein 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:N4BP2L2
Synonyms:CG005, PFAAP5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000244754.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26916 N4BP2L2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615788 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q92802

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10443

Open Targets

More...
OpenTargetsi
ENSG00000244754

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162396632

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
N4BP2L2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751659

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002990261 – 583NEDD4-binding protein 2-like 2Add BLAST583

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q92802

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q92802

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q92802

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q92802

PeptideAtlas

More...
PeptideAtlasi
Q92802

PRoteomics IDEntifications database

More...
PRIDEi
Q92802

ProteomicsDB human proteome resource

More...
ProteomicsDBi
75485
75486 [Q92802-2]
75487 [Q92802-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q92802

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q92802

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000244754 Expressed in 236 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q92802 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q92802 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039338
HPA039434
HPA059327

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115708, 38 interactors

Protein interaction database and analysis system

More...
IntActi
Q92802, 26 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000382328

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q92802

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q92802

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili162 – 197Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi558 – 561Poly-Pro4

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2401 Eukaryota
ENOG41101K4 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161440

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113715

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG059710

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q92802

Identification of Orthologs from Complete Genome Data

More...
OMAi
RHSVYFY

Database of Orthologous Groups

More...
OrthoDBi
1032689at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q92802

TreeFam database of animal gene trees

More...
TreeFami
TF336975

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026568 NEDD4-bind_pro_2-like_2
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR13308:SF23 PTHR13308:SF23, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q92802-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSYGEIEGKF LGPREEVTSE PRCKKLKSTT ESYVFHNHSN ADFHRIQEKT
60 70 80 90 100
GNDWVPVTII DVRGHSYLQE NKIKTTDLHR PLHDEMPGNR PDVIESIDSQ
110 120 130 140 150
VLQEARPPLV SADDEIYSTS KAFIGPIYKP PEKKKRNEGR NEAHVLNGIN
160 170 180 190 200
DRGGQKEKQK FNSEKSEIDN ELFQFYKEIE ELEKEKDGFE NSCKESEPSQ
210 220 230 240 250
EQFVPFYEGH NNGLLKPDEE KKDLSNKAMP SHCDYQQNLG NEPDKYPCNG
260 270 280 290 300
QVIPTFCDTS FTSFRPEWQS VYPFIVPYGP PLPSLNYHLN IQRFSGPPNP
310 320 330 340 350
PSNIFQAQDD SQIQNGYYVN NCHVNWNCMT FDQNNEYTDC SENRSSVHPS
360 370 380 390 400
GNGCSMQDRY VSNGFCEVRE RCWKDHCMDK HNGTDRFVNQ QFQEEKLNKL
410 420 430 440 450
QKLLILLRGL PGSGKTTLSR ILLGQNRDGI VFSTDDYFHH QDGYRYNVNQ
460 470 480 490 500
LGDAHDWNQN RAKQAIDQGR SPVIIDNTNI QAWEMKPYVE VAIGKGYRVE
510 520 530 540 550
FHEPETWWKF DPEELEKRNK HGVSRKKIAQ MLDRYEYQMS ISIVMNSVEP
560 570 580
SHKSTQRPPP PQGRQRWGGS LGSHNRVCVT NNH
Length:583
Mass (Da):67,459
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i318DC4D81CD0FF2A
GO
Isoform 2 (identifier: Q92802-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     567-583: WGGSLGSHNRVCVTNNH → FDRKLKRWEE...SVEKRQKKIG

Note: No experimental confirmation available.
Show »
Length:655
Mass (Da):76,082
Checksum:i6CD19BF77B1925BC
GO
Isoform 3 (identifier: Q92802-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     8-32: GKFLGPREEVTSEPRCKKLKSTTES → EFCLVRIVMALCSALMTIFTIKMGT
     33-461: Missing.
     566-583: RWGGSLGSHNRVCVTNNH → RERVLKKTGH...SVEKRQKKIG

Show »
Length:752
Mass (Da):87,169
Checksum:iAA8CC83570FF4F1A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DPY1B4DPY1_HUMAN
NEDD4-binding protein 2-like 2
N4BP2L2
737Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R968D6R968_HUMAN
NEDD4-binding protein 2-like 2
N4BP2L2
709Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI31632 differs from that shown. Contaminating sequence. Sequence of unknown origin in the N-terminal part.Curated
The sequence BP361938 differs from that shown. Reason: Frameshift at several positions.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034765272Y → H. Corresponds to variant dbSNP:rs34062461Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0413378 – 32GKFLG…STTES → EFCLVRIVMALCSALMTIFT IKMGT in isoform 3. CuratedAdd BLAST25
Alternative sequenceiVSP_04133833 – 461Missing in isoform 3. CuratedAdd BLAST429
Alternative sequenceiVSP_041339566 – 583RWGGS…VTNNH → RERVLKKTGHRLSKTKQKRN RKRNKKQNSQNRIMEENSLE FLSDLTPGDQDPSQSEEEDI EKTRRESEYPFIDGLQNEVG DFVTGYKEKRWKNKDPKDSF QNVMSIVELDNTPKNYLSKE GDNLFVSLLLRPNEISVTCP ILTQNLSCVTTDDCSGMKVE KHIRNRHTIALDTQDLSAET SCLFMKKREIVDKNLSHEPI LCHQHGIRMSDKVLREEQVY TTKINHWAFFTTNLSDEDLQ LGSDRQPYFGSWPAGPHKFI CEQRPKKDRACKLAGPDSRG QWIQMIFTSVAASEPGNNPE ILTDKLLIGNEDFSPPPETM DSFIETNLFRSCLPQPDIPK NALESTKNKKRRKKRIFNLV PNFDLLGQSRIGVKEREKCD LLTKNHGLKITLGEEKDRIS ERNSEEENKQKLMTFDHHPL WFYLDIIKATPLNIDGQRYS HCLSFNRLRCSASLYKNYIP SFVLHNLSSIWKPSFTNKKL FLTFESQTRVGNKLNDAGFI SPEILHSHPDTSCSLGVTSD FHFLNERFDRKLKRWEEPKE LPAEDSQDLTSTDYRSLELP LSQGFAFQLVKLFGSPGVPM ESLLPDDYVVPLDWKTLKMI YLQWKMSVEKRQKKIG in isoform 3. CuratedAdd BLAST18
Alternative sequenceiVSP_027518567 – 583WGGSL…VTNNH → FDRKLKRWEEPKELPAEDSQ DLTSTDYRSLELPLSQGFAF QLVKLFGSPGVPMESLLPDD YVVPLDWKTLKMIYLQWKMS VEKRQKKIG in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U50532 mRNA Translation: AAC50875.1
AF530063 mRNA Translation: AAQ09947.1
AL049783 mRNA Translation: CAB42441.1
BT007172 mRNA Translation: AAP35836.1
AL353665 Genomic DNA No translation available.
CH471075 Genomic DNA Translation: EAX08514.1
BC010643 mRNA Translation: AAH10643.1
BC131631 mRNA Translation: AAI31632.1 Sequence problems.
BP361938 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45024.1 [Q92802-3]
CCDS9346.1 [Q92802-1]

NCBI Reference Sequences

More...
RefSeqi
NP_055702.1, NM_014887.2 [Q92802-1]
XP_016875836.1, XM_017020347.1 [Q92802-1]
XP_016875837.1, XM_017020348.1 [Q92802-1]
XP_016875838.1, XM_017020349.1 [Q92802-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.507680

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000267068; ENSP00000267068; ENSG00000244754 [Q92802-1]
ENST00000399396; ENSP00000382328; ENSG00000244754 [Q92802-3]
ENST00000446957; ENSP00000394239; ENSG00000244754 [Q92802-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10443

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10443

UCSC genome browser

More...
UCSCi
uc001uuk.5 human [Q92802-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50532 mRNA Translation: AAC50875.1
AF530063 mRNA Translation: AAQ09947.1
AL049783 mRNA Translation: CAB42441.1
BT007172 mRNA Translation: AAP35836.1
AL353665 Genomic DNA No translation available.
CH471075 Genomic DNA Translation: EAX08514.1
BC010643 mRNA Translation: AAH10643.1
BC131631 mRNA Translation: AAI31632.1 Sequence problems.
BP361938 mRNA No translation available.
CCDSiCCDS45024.1 [Q92802-3]
CCDS9346.1 [Q92802-1]
RefSeqiNP_055702.1, NM_014887.2 [Q92802-1]
XP_016875836.1, XM_017020347.1 [Q92802-1]
XP_016875837.1, XM_017020348.1 [Q92802-1]
XP_016875838.1, XM_017020349.1 [Q92802-1]
UniGeneiHs.507680

3D structure databases

ProteinModelPortaliQ92802
SMRiQ92802
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115708, 38 interactors
IntActiQ92802, 26 interactors
STRINGi9606.ENSP00000382328

PTM databases

iPTMnetiQ92802
PhosphoSitePlusiQ92802

Polymorphism and mutation databases

BioMutaiN4BP2L2
DMDMi74751659

Proteomic databases

EPDiQ92802
jPOSTiQ92802
MaxQBiQ92802
PaxDbiQ92802
PeptideAtlasiQ92802
PRIDEiQ92802
ProteomicsDBi75485
75486 [Q92802-2]
75487 [Q92802-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10443
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000267068; ENSP00000267068; ENSG00000244754 [Q92802-1]
ENST00000399396; ENSP00000382328; ENSG00000244754 [Q92802-3]
ENST00000446957; ENSP00000394239; ENSG00000244754 [Q92802-2]
GeneIDi10443
KEGGihsa:10443
UCSCiuc001uuk.5 human [Q92802-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10443
DisGeNETi10443
EuPathDBiHostDB:ENSG00000244754.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
N4BP2L2
HGNCiHGNC:26916 N4BP2L2
HPAiHPA039338
HPA039434
HPA059327
MIMi615788 gene
neXtProtiNX_Q92802
OpenTargetsiENSG00000244754
PharmGKBiPA162396632

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2401 Eukaryota
ENOG41101K4 LUCA
GeneTreeiENSGT00940000161440
HOGENOMiHOG000113715
HOVERGENiHBG059710
InParanoidiQ92802
OMAiRHSVYFY
OrthoDBi1032689at2759
PhylomeDBiQ92802
TreeFamiTF336975

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
N4BP2L2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10443

Protein Ontology

More...
PROi
PR:Q92802

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000244754 Expressed in 236 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ92802 baseline and differential
GenevisibleiQ92802 HS

Family and domain databases

InterProiView protein in InterPro
IPR026568 NEDD4-bind_pro_2-like_2
IPR027417 P-loop_NTPase
PANTHERiPTHR13308:SF23 PTHR13308:SF23, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiN42L2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92802
Secondary accession number(s): A3KME8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 1, 1997
Last modified: February 13, 2019
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again