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Protein

Putative zinc finger protein 75C

Gene

ZNF75CP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

May be involved in transcriptional regulation.

Caution

Could be the product of a pseudogene.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri292 – 314C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 5PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc finger protein 75C
Alternative name(s):
Zinc finger protein 75C pseudogene
Gene namesi
Name:ZNF75CP
Synonyms:ZNF75C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:13148 ZNF75CP
neXtProtiNX_Q92670

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi205831223

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003492421 – 426Putative zinc finger protein 75CAdd BLAST426

Proteomic databases

PeptideAtlasiQ92670
PRIDEiQ92670
ProteomicsDBi75401

PTM databases

iPTMnetiQ92670
PhosphoSitePlusiQ92670

Structurei

3D structure databases

ProteinModelPortaliQ92670
SMRiQ92670
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 131SCAN boxPROSITE-ProRule annotationAdd BLAST83
Domaini205 – 289KRABPROSITE-ProRule annotationAdd BLAST85

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri292 – 314C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 5PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG018163
InParanoidiQ92670
PhylomeDBiQ92670

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
cd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequencei

Sequence statusi: Complete.

Q92670-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIMRELKADA CLNSHMGAMW ETNRSVKENS SQSKKYSTQI ECLSPGSACR
60 70 80 90 100
HFRSFHYHEA TEPLEAINQL QKLCHQWLRP EIHSKKHILE MLVLEHFLTI
110 120 130 140 150
LPKGTQNWVQ KHHPQLAKQA LVLVERLQRE PGGTKNEVTA HELGEEAVLL
160 170 180 190 200
RGTTVAPGFK WKPAELEPME RILEHIQILA LSEHKSTKDW KMAPKLIWPE
210 220 230 240 250
SQSLLTFEDM AVYFSEEEWQ LLGPLEKTLY NDVMQDIYET AISLGKQRTG
260 270 280 290 300
KIMGIEMASS FSKEEKKLTT CKQELPKLMD LHGKGHTGEK PFKCQDCGKI
310 320 330 340 350
FRVSSDLIKH QRIHTEEKLY KCQQCDRRFR WSSGLNKHFM THQGINPYRC
360 370 380 390 400
SWYGKSISYD TNLQTHQRIH TGEKPFKCHE CGKIFIHKSN LIKYQRTHTG
410 420
EQPYTCSICR RNFSRQLSLL RHQKLH
Length:426
Mass (Da):49,753
Last modified:September 2, 2008 - v2
Checksum:iF88B9E97A42FA06B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti394Y → H in CAA62937 (PubMed:8661144).Curated1
Sequence conflicti408 – 410ICR → LCK in CAA62937 (PubMed:8661144).Curated3
Sequence conflicti416 – 417QL → RS in CAA62937 (PubMed:8661144).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003086 Genomic DNA No translation available.
X91828 Genomic DNA Translation: CAA62937.1

Similar proteinsi

Entry informationi

Entry nameiZN75C_HUMAN
AccessioniPrimary (citable) accession number: Q92670
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 12, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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