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1 to 25 of 49  Show
  1. 1
    "Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases."
    Becker W., Weber Y., Wetzel K., Eirmbter K., Tejedor F.J., Joost H.-G.
    J. Biol. Chem. 273:25893-25902(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, COFACTOR, PHOSPHORYLATION, TISSUE SPECIFICITY.
    Category: Function, PTM / Processing, Expression, Sequences.
    Tissue: Fetal brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 and mapped to 18 other entries.

  2. 2
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12930 other entries.

  3. 3
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Category: Sequences.
    Tissue: Muscle and Skin.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50477 other entries.

  5. 5
    Becker W., Joost H.-G.
    Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 320-528 (ISOFORMS 1/2).
    Category: Sequences.
    Tissue: Placenta.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase."
    Woods Y.L., Cohen P., Becker W., Jakes R., Goedert M., Wang X., Proud C.G.
    Biochem. J. 355:609-615(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  7. 7
    "Amplification and overexpression of the dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinomas."
    Miller C.T., Aggarwal S., Lin T.K., Dagenais S.L., Contreras J.I., Orringer M.B., Glover T.W., Beer D.G., Lin L.
    Cancer Res. 63:4136-4143(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION IN CANCER.
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation."
    Wang X., Li W., Parra J.L., Beugnet A., Proud C.G.
    Mol. Cell. Biol. 23:1546-1557(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  9. 9
    "Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases."
    Skurat A.V., Dietrich A.D.
    J. Biol. Chem. 279:2490-2498(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  10. 10
    "Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors."
    de Graaf K., Hekerman P., Spelten O., Herrmann A., Packman L.C., Bussow K., Muller-Newen G., Becker W.
    J. Biol. Chem. 279:4612-4624(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CCNL2.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL."
    Auld G.C., Campbell D.G., Morrice N., Cohen P.
    Biochem. J. 389:775-783(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  12. 12
    "Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo."
    Cole A.R., Causeret F., Yadirgi G., Hastie C.J., McLauchlan H., McManus E.J., Hernandez F., Eickholt B.J., Nikolic M., Sutherland C.
    J. Biol. Chem. 281:16591-16598(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION AS CRMP4/DPYSL3 KINASE, ACTIVITY REGULATION BY PURVALANOL.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 28 other entries.

  13. 13
    "A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT."
    Gwack Y., Sharma S., Nardone J., Tanasa B., Iuga A., Srikanth S., Okamura H., Bolton D., Feske S., Hogan P.G., Rao A.
    Nature 441:646-650(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH NFATC1.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 8 other entries.

  14. 14
    "DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage."
    Taira N., Nihira K., Yamaguchi T., Miki Y., Yoshida K.
    Mol. Cell 25:725-738(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 143 other entries.

  15. 15
    "Role for DYRK family kinases on regulation of apoptosis."
    Yoshida K.
    Biochem. Pharmacol. 76:1389-1394(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN APOPTOSIS AS P53/TP53 KINASE, SUBCELLULAR LOCATION, PHOSPHORYLATION BY ATM, GENE FAMILY.
    Category: Function, Subcellular Location, PTM / Processing, Names & Taxonomy, Family & Domains.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  16. 16
    "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling."
    Varjosalo M., Bjorklund M., Cheng F., Syvanen H., Kivioja T., Kilpinen S., Sun Z., Kallioniemi O., Stunnenberg H.G., He W.W., Ojala P., Taipale J.
    Cell 133:537-548(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, PHOSPHORYLATION AT THR-381 AND SER-449.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 13 other entries.

  17. 17
    "Nuclear trafficking of pro-apoptotic kinases in response to DNA damage."
    Yoshida K.
    Trends Mol. Med. 14:305-313(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
    Category: Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).
  18. 18
    "Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation."
    Goeckler N., Jofre G., Papadopoulos C., Soppa U., Tejedor F.J., Becker W.
    FEBS J. 276:6324-6337(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACTIVITY REGULATION BY HARMINE.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  19. 19
    "Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase."
    Maddika S., Chen J.
    Nat. Cell Biol. 11:409-419(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN E3 LIGASE REGULATION, FUNCTION AS KATNA1 KINASE, INTERACTION WITH EDVP COMPLEX.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  20. 20
    "Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors."
    Cuny G.D., Robin M., Ulyanova N.P., Patnaik D., Pique V., Casano G., Liu J.-F., Lin X., Xian J., Glicksman M.A., Stein R.L., Higgins J.M.G.
    Bioorg. Med. Chem. Lett. 20:3491-3494(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACTIVITY REGULATION BY ACRIDINE ANALOGS.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  21. 21
    "ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage."
    Taira N., Yamamoto H., Yamaguchi T., Miki Y., Yoshida K.
    J. Biol. Chem. 285:4909-4919(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, PHOSPHORYLATION AT THR-106 AND SER-442 BY ATM, UBIQUITINATION BY MDM2, INTERACTION WITH MDM2, MUTAGENESIS OF THR-106; SER-442 AND 189-LYS--ARG-191, NUCLEAR LOCALIZATION SIGNAL, INDUCTION BY DNA DAMAGE.
    Category: Subcellular Location, Pathology & Biotech, PTM / Processing, Expression, Interaction, Family & Domains.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 6 other entries.

  22. 22
    "DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells."
    Taira N., Mimoto R., Kurata M., Yamaguchi T., Kitagawa M., Miki Y., Yoshida K.
    J. Clin. Invest. 122:859-872(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 67 other entries.

  23. 23
    "Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways."
    Perez M., Garcia-Limones C., Zapico I., Marina A., Schmitz M.L., Munoz E., Calzado M.A.
    J. Mol. Cell Biol. 4:316-330(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, UBIQUITINATION BY SIAH2.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 2 other entries.

  24. 24
    "Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation."
    Jung H.Y., Wang X., Jun S., Park J.I.
    J. Biol. Chem. 288:7252-7262(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, MUTAGENESIS OF LYS-251.
    Category: Function, Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 10 other entries.

  25. 25
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-30, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13318 other entries.

1 to 25 of 49  Show
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