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Entry version 153 (16 Oct 2019)
Sequence version 1 (01 Feb 1997)
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Protein

Protein Jade-3

Gene

JADE3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri200 – 250PHD-type 1PROSITE-ProRule annotationAdd BLAST51
Zinc fingeri252 – 286C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST35
Zinc fingeri310 – 366PHD-type 2PROSITE-ProRule annotationAdd BLAST57

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-3214847 HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein Jade-3
Alternative name(s):
Jade family PHD finger protein 3
PHD finger protein 16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:JADE3
Synonyms:KIAA0215, PHF16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:22982 JADE3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300618 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q92613

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000102221

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134993233

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q92613

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
JADE3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
34098663

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000593091 – 823Protein Jade-3Add BLAST823

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei30N6-acetyllysineCombined sources1
Modified residuei32N6-acetyllysineCombined sources1
Modified residuei85PhosphoserineCombined sources1
Modified residuei566PhosphoserineCombined sources1
Modified residuei601N6-acetyllysineBy similarity1
Modified residuei608PhosphoserineCombined sources1
Modified residuei638N6-acetyllysineCombined sources1
Modified residuei735N6-acetyllysineBy similarity1
Modified residuei774PhosphoserineCombined sources1
Modified residuei776PhosphoserineCombined sources1
Modified residuei780PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q92613

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q92613

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q92613

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q92613

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q92613

PeptideAtlas

More...
PeptideAtlasi
Q92613

PRoteomics IDEntifications database

More...
PRIDEi
Q92613

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
75357

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q92613

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q92613

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed, with highest levels in placenta and uterus.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By estradiol in estrogen-responsive breast cancer cells.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000102221 Expressed in 192 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q92613 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q92613 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA006007
HPA064697

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
MAGEA11P43364-23EBI-10278909,EBI-10178634

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115113, 15 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-720 HBO1-4.3 histone acetyltransferase complex
CPX-723 HBO1-5.3 histone acetyltransferase complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q92613

Protein interaction database and analysis system

More...
IntActi
Q92613, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000481850

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q92613

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the JADE family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri200 – 250PHD-type 1PROSITE-ProRule annotationAdd BLAST51
Zinc fingeri252 – 286C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST35
Zinc fingeri310 – 366PHD-type 2PROSITE-ProRule annotationAdd BLAST57

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0954 Eukaryota
COG5141 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158722

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000220882

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q92613

KEGG Orthology (KO)

More...
KOi
K22156

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSTMEHF

Database of Orthologous Groups

More...
OrthoDBi
1235709at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q92613

TreeFam database of animal gene trees

More...
TreeFami
TF316118

Family and domain databases

Conserved Domains Database

More...
CDDi
cd15681 PHD_JADE3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019542 Enhancer_polycomb-like_N
IPR034732 EPHD
IPR039550 JADE3_PHD
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10513 EPL1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00249 PHD, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51805 EPHD, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q92613-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRHRPVSSS DSSDESPSTS FTSGSMYRIK SKIPNEHKKP AEVFRKDLIS
60 70 80 90 100
AMKLPDSHHI NPDSYYLFAD TWKEEWEKGV QVPASPDTVP QPSLRIIAEK
110 120 130 140 150
VKDVLFIRPR KYIHCSSPDT TEPGYINIME LAASVCRYDL DDMDIFWLQE
160 170 180 190 200
LNEDLAEMGC GPVDENLMEK TVEVLERHCH ENMNHAIETE EGLGIEYDED
210 220 230 240 250
VICDVCRSPD SEEGNDMVFC DKCNVCVHQA CYGILKVPEG SWLCRSCVLG
260 270 280 290 300
IYPQCVLCPK KGGALKTTKT GTKWAHVSCA LWIPEVSIAC PERMEPITKI
310 320 330 340 350
SHIPPSRWAL VCNLCKLKTG ACIQCSIKSC ITAFHVTCAF EHGLEMKTIL
360 370 380 390 400
DEGDEVKFKS YCLKHSQNRQ KLGEAEYPHH RAKEQSQAKS EKTSLRAQKL
410 420 430 440 450
RELEEEFYSL VRVEDVAAEL GMPTLAVDFI YNYWKLKRKS NFNKPLFPPK
460 470 480 490 500
EDEENGLVQP KEESIHTRMR MFMHLRQDLE RVRNLCYMIS RREKLKLSHN
510 520 530 540 550
KIQEQIFGLQ VQLLNQEIDA GLPLTNALEN SLFYPPPRIT LKLKMPKSTP
560 570 580 590 600
EDHRNSSTET DQQPHSPDSS SSVHSIRNMQ VPQESLEMRT KSYPRYPLES
610 620 630 640 650
KNNRLLASLS HSRSEAKESS PAWRTPSSEC YHGQSLGKPL VLQAALHGQS
660 670 680 690 700
SIGNGKSQPN SKFAKSNGLE GSWSGNVTQK DSSSEMFCDQ EPVFSPHLVS
710 720 730 740 750
QGSFRKSTVE HFSRSFKETT NRWVKNTEDL QCYVKPTKNM SPKEQFWGRQ
760 770 780 790 800
VLRRSAGRAP YQENDGYCPD LELSDSEAES DGNKEKVRVR KDSSDRENPP
810 820
HDSRRDCHGK SKTHPLSHSS MQR
Length:823
Mass (Da):93,808
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E47E2A124D0CE38
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z3N8F2Z3N8_HUMAN
Protein Jade-3
JADE3
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z2B6F2Z2B6_HUMAN
Protein Jade-3
JADE3
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA13205 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF127774 mRNA Translation: AAD51905.1
D86969 mRNA Translation: BAA13205.2 Different initiation.
Z83822 Genomic DNA No translation available.
BC114487 mRNA Translation: AAI14488.1
BC113880 mRNA Translation: AAI13881.1
BN000289 mRNA Translation: CAE30502.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS14271.1

NCBI Reference Sequences

More...
RefSeqi
NP_001070913.1, NM_001077445.2
NP_055550.1, NM_014735.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000611250; ENSP00000479377; ENSG00000102221
ENST00000614628; ENSP00000481850; ENSG00000102221

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9767

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9767

UCSC genome browser

More...
UCSCi
uc033ebv.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF127774 mRNA Translation: AAD51905.1
D86969 mRNA Translation: BAA13205.2 Different initiation.
Z83822 Genomic DNA No translation available.
BC114487 mRNA Translation: AAI14488.1
BC113880 mRNA Translation: AAI13881.1
BN000289 mRNA Translation: CAE30502.1
CCDSiCCDS14271.1
RefSeqiNP_001070913.1, NM_001077445.2
NP_055550.1, NM_014735.4

3D structure databases

SMRiQ92613
ModBaseiSearch...

Protein-protein interaction databases

BioGridi115113, 15 interactors
ComplexPortaliCPX-720 HBO1-4.3 histone acetyltransferase complex
CPX-723 HBO1-5.3 histone acetyltransferase complex
CORUMiQ92613
IntActiQ92613, 12 interactors
STRINGi9606.ENSP00000481850

PTM databases

iPTMnetiQ92613
PhosphoSitePlusiQ92613

Polymorphism and mutation databases

BioMutaiJADE3
DMDMi34098663

Proteomic databases

EPDiQ92613
jPOSTiQ92613
MassIVEiQ92613
MaxQBiQ92613
PaxDbiQ92613
PeptideAtlasiQ92613
PRIDEiQ92613
ProteomicsDBi75357

Genome annotation databases

EnsembliENST00000611250; ENSP00000479377; ENSG00000102221
ENST00000614628; ENSP00000481850; ENSG00000102221
GeneIDi9767
KEGGihsa:9767
UCSCiuc033ebv.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9767

GeneCards: human genes, protein and diseases

More...
GeneCardsi
JADE3
HGNCiHGNC:22982 JADE3
HPAiHPA006007
HPA064697
MIMi300618 gene
neXtProtiNX_Q92613
OpenTargetsiENSG00000102221
PharmGKBiPA134993233

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0954 Eukaryota
COG5141 LUCA
GeneTreeiENSGT00940000158722
HOGENOMiHOG000220882
InParanoidiQ92613
KOiK22156
OMAiKSTMEHF
OrthoDBi1235709at2759
PhylomeDBiQ92613
TreeFamiTF316118

Enzyme and pathway databases

ReactomeiR-HSA-3214847 HATs acetylate histones

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
JADE3 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
PHF16

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
9767
PharosiQ92613

Protein Ontology

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PROi
PR:Q92613

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000102221 Expressed in 192 organ(s), highest expression level in female gonad
ExpressionAtlasiQ92613 baseline and differential
GenevisibleiQ92613 HS

Family and domain databases

CDDicd15681 PHD_JADE3, 1 hit
Gene3Di3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR019542 Enhancer_polycomb-like_N
IPR034732 EPHD
IPR039550 JADE3_PHD
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF10513 EPL1, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 2 hits
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS51805 EPHD, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJADE3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92613
Secondary accession number(s): Q6IE79
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: February 1, 1997
Last modified: October 16, 2019
This is version 153 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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