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Protein

Mediator of RNA polymerase II transcription subunit 1

Gene

Med1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Essential for embryogenesis, including development of the central nervous system, heart, liver and placenta and for erythropoiesis. Also required for normal transcriptional control of thyroid-stimulating hormone beta (TSHB) in the pituitary. Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (By similarity).By similarity10 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-MMU-212436 Generic Transcription Pathway
R-MMU-383280 Nuclear Receptor transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-9018519 Estrogen-dependent gene expression

Names & Taxonomyi

Protein namesi
Recommended name:
Mediator of RNA polymerase II transcription subunit 1
Alternative name(s):
Mediator complex subunit 1
Peroxisome proliferator-activated receptor-binding protein
Short name:
PBP
Short name:
PPAR-binding protein
Thyroid hormone receptor-associated protein complex 220 kDa component
Short name:
Trap220
Thyroid receptor-interacting protein 2
Short name:
TR-interacting protein 2
Short name:
TRIP-2
Gene namesi
Name:Med1
Synonyms:Crsp210, Drip205, Pbp, Pparbp, Trap220, Trip2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1100846 Med1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000585531 – 1575Mediator of RNA polymerase II transcription subunit 1Add BLAST1575

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei588PhosphoserineBy similarity1
Modified residuei664PhosphoserineCombined sources1
Modified residuei795PhosphoserineBy similarity1
Modified residuei805PhosphothreonineCombined sources1
Modified residuei953PhosphoserineCombined sources1
Modified residuei955PhosphoserineCombined sources1
Modified residuei1032Phosphothreonine; by MAPK1 or MAPK3By similarity1
Modified residuei1051PhosphothreonineCombined sources1
Modified residuei1057PhosphothreonineCombined sources1
Modified residuei1158PhosphoserineCombined sources1
Modified residuei1179N6-acetyllysineBy similarity1
Modified residuei1209PhosphoserineCombined sources1
Modified residuei1217PhosphothreonineBy similarity1
Modified residuei1225PhosphoserineBy similarity1
Modified residuei1304PhosphoserineBy similarity1
Modified residuei1349PhosphoserineBy similarity1
Modified residuei1405PhosphoserineBy similarity1
Modified residuei1435PhosphoserineCombined sources1
Modified residuei1442PhosphothreonineCombined sources1
Modified residuei1459Phosphothreonine; by MAPK1 or MAPK3By similarity1
Modified residuei1465PhosphoserineCombined sources1
Modified residuei1467PhosphoserineCombined sources1
Modified residuei1481PhosphoserineCombined sources1
Modified residuei1483PhosphoserineBy similarity1
Modified residuei1484PhosphoserineCombined sources1
Modified residuei1523N6-acetyllysineBy similarity1

Post-translational modificationi

Phosphorylated by MAPK1 or MAPK3 during G2/M phase which may enhance protein stability and promote entry into the nucleolus.By similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ925J9
PaxDbiQ925J9
PeptideAtlasiQ925J9
PRIDEiQ925J9

PTM databases

iPTMnetiQ925J9
PhosphoSitePlusiQ925J9

Expressioni

Tissue specificityi

Widely expressed in the adult, with high levels of expression in the liver, lung, intestinal mucosa, kidney cortex, thymic cortex, splenic follicle and seminiferous epithelium in testis. Also expressed in the adult heart, brain, spleen and skeletal muscle.2 Publications

Developmental stagei

Widely expressed during embryonic development; at stages E9.5-10.5, expression is strongest in neural tissues. At E11.5-E12.5, expression is abundant throughout embryonic tissues, being strongest in the developing liver, primitive gut, nasopharynx, and developing limb buds. Moderately expressed at this stage in the brain and optic stalk, branchial arch and urogential ridge. Expressed at a low level in the heart. By stage E13.5-E14.5, expression is abundant in the forebrain, vagus nerve, dorsal root ganglia, nasopharynx, kidney, liver, pancreas, intestine, gut, thymus, lung, genital tubercle, tongue and lower jaw. Moderately expressed in the midbrain and expressed at a low level in the heart and large blood vessels. In the developing placenta, expression is moderate in the giant and spongiotrophoblast cell layers and strongest in the labyrinthine portion throughout E9.5-E13.5.2 Publications

Gene expression databases

BgeeiENSMUSG00000018160 Expressed in 296 organ(s), highest expression level in rostral migratory stream
CleanExiMM_MED1
ExpressionAtlasiQ925J9 baseline and differential
GenevisibleiQ925J9 MM

Interactioni

Subunit structurei

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. This subunit specifically interacts with a number of nuclear receptors in a ligand-dependent fashion including AR, ESR1, ESR2, PPARA, PPARG, RORA, RXRA, RXRG, THRA, THRB and VDR. Interacts with CTNNB1, GABPA, GLI3, PPARGC1A and TP53. Interacts with GATA1 and YWHAH. Interacts with CLOCK; this interaction requires the presence of THRAP3. Interacts with CCAR1 (By similarity). Interacts with NR4A3 (PubMed:12709428).By similarity9 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi202318, 5 interactors
ComplexPortaliCPX-3264 Core mediator complex
CORUMiQ925J9
DIPiDIP-59232N
ELMiQ925J9
IntActiQ925J9, 10 interactors
MINTiQ925J9
STRINGi10090.ENSMUSP00000103169

Structurei

Secondary structure

11575
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ925J9
SMRiQ925J9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ925J9

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 670Interaction with the Mediator complex and THRABy similarityAdd BLAST670
Regioni16 – 590Interaction with ESR1By similarityAdd BLAST575
Regioni108 – 212Interaction with the Mediator complexBy similarityAdd BLAST105
Regioni215 – 390Interaction with the Mediator complexBy similarityAdd BLAST176
Regioni405 – 644Interaction with THRABy similarityAdd BLAST240
Regioni542 – 789Interaction with VDRBy similarityAdd BLAST248
Regioni622 – 701Interaction with GATA11 PublicationAdd BLAST80
Regioni622 – 701Interaction with PPARGC1A and THRABy similarityAdd BLAST80
Regioni656 – 1066Interaction with ESR1By similarityAdd BLAST411
Regioni1251 – 1423Interaction with TP53By similarityAdd BLAST173

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi604 – 608LXXLL motif 15
Motifi645 – 649LXXLL motif 25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1078 – 1484Ser-richSequence analysisAdd BLAST407
Compositional biasi1498 – 1523Lys-richSequence analysisAdd BLAST26

Sequence similaritiesi

Belongs to the Mediator complex subunit 1 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IEFR Eukaryota
ENOG410XR2E LUCA
GeneTreeiENSGT00660000095569
HOVERGENiHBG101127
InParanoidiQ925J9
KOiK15144
OMAiHPMLMNL
OrthoDBiEOG091G035E
PhylomeDBiQ925J9
TreeFamiTF324954

Family and domain databases

InterProiView protein in InterPro
IPR019680 Mediator_Med1
PfamiView protein in Pfam
PF10744 Med1, 1 hit

Sequences (4+)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q925J9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKAQGETEDS ERLSKMSSLL ERLHAKFNQN RPWSETIKLV RQVMEKRVVM
60 70 80 90 100
SSGGHQHLVS CLETLQKALK VTSLPAMTDR LESIARQNGL GSHLSASGTE
110 120 130 140 150
CYITSDMFYV EVQLDPAGQL CDVKVAHHGE NPVSCPELVQ QLREKNFEEF
160 170 180 190 200
SKHLKGLVNL YNLPGDNKLK TKMYLALQSL EQDLSKMAIM YWKATNAAPL
210 220 230 240 250
DKILHGSVGY LTPRSGGHLM NMKYYASPSD LLDDKTASPI ILHEKNVPRS
260 270 280 290 300
LGMNASVTIE GTSAMYKLPI APLIMGSHPA DNKWTPSFSA VTSANSVDLP
310 320 330 340 350
ACFFLKFPQP IPVSKAFVQK LQNCTGIPLF ETPPTYLPLY ELITQFELSK
360 370 380 390 400
DPDPLPLNHN MRFYAALPGQ QHCYFLNKDA PLPDGQSLQG TLVSKITFQH
410 420 430 440 450
PGRVPLILNM IRHQVAYNTL IGSCVKRTIL KEDSPGLLQF EVCPLSESRF
460 470 480 490 500
SVSFQHPVND SLVCVVMDVQ DSTHVSCKLY KGLSDALICT DDFIAKVVQR
510 520 530 540 550
CMSIPVTMRA IRRKAETIQA DTPALSLIAE TVEDMVKKNL PPASSPGYGM
560 570 580 590 600
TTGNNPMSGT TTPTNTFPGG PITTLFNMSM SIKDRHESVG HGEDFSKVSQ
610 620 630 640 650
NPILTSLLQI TGNGGSTIGS SPTPPHHTPP PVSSMAGNTK NHPMLMNLLK
660 670 680 690 700
DNPAQDFSTL YGSSPLERQN SSSGSPRMEM CSGSNKAKKK KSSRVPPDKP
710 720 730 740 750
KHQTEDDFQR ELFSMDVDSQ NPMFDVSMTA DALDTPHITP APSQCSTPPA
760 770 780 790 800
TYPQPVSHPQ PSIQRMVRLS SSDSIGPDVT DILSDIAEEA SKLPSTSDDC
810 820 830 840 850
PPIGTPVRDS SSSGHSQSAL FDSDVFQTNN NENPYTDPAD LIADAAGSPN
860 870 880 890 900
SDSPTNHFFP DGVDFNPDLL NSQSQSGFGE EYFDESSQSG DNDDFKGFAS
910 920 930 940 950
QALNTLGMPM LGGDNGEPKF KGSSQADTVD FSIISVAGKA LGAADLMEHH
960 970 980 990 1000
SGSQSPLLTT GELGKEKTQK RVKEGNGTGA SSGSGPGSDS KPGKRSRTPS
1010 1020 1030 1040 1050
NDGKSKDKPP KRKKADTEGK SPSHSSSNRP FTPPTSTGGS KSPGSSGRSQ
1060 1070 1080 1090 1100
TPPGVATPPI PKITIQIPKG TVMVGKPSSH SQYTSSGSVS SSGSKSHHSH
1110 1120 1130 1140 1150
SSSSSSLASA STSGKVKSSK SEGSSSSKLS GSMYASQGSS GSSQSKNSSQ
1160 1170 1180 1190 1200
TGGKPGSSPI TKHGLSSGSS STKMKPQGKP SSLMNPSISK PNISPSHSRP
1210 1220 1230 1240 1250
PGGSDKLASP MKPVPGTPPS SKAKSPISSG SSGSHVSGTS SSSGMKSSSG
1260 1270 1280 1290 1300
SASSGSVSQK TPPASNSCTP SSSSFSSSGS SMSSSQNQHG SSKGKSPSRN
1310 1320 1330 1340 1350
KKPSLTAVID KLKHGVVTSG PGGEDPIDSQ MGASTNSSNH PMSSKHNTSG
1360 1370 1380 1390 1400
GEFQSKREKS DKDKSKVSAS GGSVDSSKKT SESKNVGSTG VAKIIISKHD
1410 1420 1430 1440 1450
GGSPSIKAKV TLQKPGESGG DGLRPQIASS KNYGSPLISG STPKHERGSP
1460 1470 1480 1490 1500
SHSKSPAYTP QNVDSESESG SSIAERSYQN SPSSEDGIRP LPEYSTEKHK
1510 1520 1530 1540 1550
KHKKEKKKVR DKDRDKKKSH SMKPENWSKS PISSDPTASV TNNPILSADR
1560 1570
PSRLSPDFMI GEEDDDLMDV ALIGN
Note: No experimental confirmation available.Curated
Length:1,575
Mass (Da):167,141
Last modified:December 6, 2005 - v2
Checksum:iC3B8121A26003A22
GO
Isoform 21 Publication (identifier: Q925J9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     548-632: YGMTTGNNPM...TPPHHTPPPV → VEEKRQDKPS...SDVQEYFSVS
     633-1575: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:632
Mass (Da):70,473
Checksum:i21A6BD89B50EA9F2
GO
Isoform 31 Publication (identifier: Q925J9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     548-556: YGMTTGNNP → SKNPELGSG
     557-1575: Missing.

Show »
Length:556
Mass (Da):61,566
Checksum:i4E8E3E79087D4B3A
GO
Isoform 42 Publications (identifier: Q925J9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-15: Missing.

Show »
Length:1,560
Mass (Da):165,450
Checksum:iC1408AE8196A6C76
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AQH6B1AQH6_MOUSE
Mediator of RNA polymerase II trans...
Med1 Pparbp, mCG_21903
629Annotation score:

Sequence cautioni

The sequence AAH21440 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti84I → L in AAC31118 (PubMed:9325263).Curated1
Sequence conflicti198A → T in AAH21440 (PubMed:15489334).Curated1
Sequence conflicti211L → H in BAE27757 (PubMed:16141072).Curated1
Sequence conflicti303F → S in AAC31118 (PubMed:9325263).Curated1
Sequence conflicti382 – 389LPDGQSLQ → VLPNKAVS in BAC35779 (PubMed:16141072).Curated8
Sequence conflicti948E → K in BAC33607 (PubMed:16141072).Curated1
Sequence conflicti964G → A in BAC33607 (PubMed:16141072).Curated1
Sequence conflicti1323G → S in AAC31118 (PubMed:9325263).Curated1
Sequence conflicti1387G → R in AAC31118 (PubMed:9325263).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti960T → S in strain: ISS and 129/Ola. 2 Publications1
Natural varianti1348T → M in strain: ISS and 129/Ola. 2 Publications1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0518921 – 15Missing in isoform 4. 2 PublicationsAdd BLAST15
Alternative sequenceiVSP_051893548 – 632YGMTT…TPPPV → VEEKRQDKPSLGHLPPIQVC SPSCLKDGKDMKSTCTYLLL LLLLLEFMVFCFFFFFLTYS SVFGLHVKGLWTKICSDVQE YFSVS in isoform 2. 1 PublicationAdd BLAST85
Alternative sequenceiVSP_051894548 – 556YGMTTGNNP → SKNPELGSG in isoform 3. 2 Publications9
Alternative sequenceiVSP_051895557 – 1575Missing in isoform 3. 2 PublicationsAdd BLAST1019
Alternative sequenceiVSP_051896633 – 1575Missing in isoform 2. 1 PublicationAdd BLAST943

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000294 mRNA Translation: AAC31118.1
AF332073 mRNA Translation: AAK56101.1
AF332074 mRNA Translation: AAK56102.1
AY176046 Genomic DNA Translation: AAN75014.1
AK049203 mRNA Translation: BAC33607.2
AK054437 mRNA Translation: BAC35779.2
AK147199 mRNA Translation: BAE27757.1
AL591205 Genomic DNA Translation: CAM21264.1
AL591205 Genomic DNA Translation: CAM21266.1
BC021440 mRNA Translation: AAH21440.1 Different initiation.
BC079636 mRNA Translation: AAH79636.1
CCDSiCCDS25341.1 [Q925J9-4]
CCDS36300.1 [Q925J9-1]
PIRiT02885
RefSeqiNP_001073587.1, NM_001080118.1 [Q925J9-1]
NP_038662.2, NM_013634.2 [Q925J9-4]
NP_598788.2, NM_134027.2 [Q925J9-3]
UniGeneiMm.12926

Genome annotation databases

EnsembliENSMUST00000018304; ENSMUSP00000018304; ENSMUSG00000018160 [Q925J9-4]
ENSMUST00000107545; ENSMUSP00000103169; ENSMUSG00000018160 [Q925J9-1]
GeneIDi19014
KEGGimmu:19014
UCSCiuc007lfo.1 mouse [Q925J9-3]
uc007lfp.1 mouse [Q925J9-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000294 mRNA Translation: AAC31118.1
AF332073 mRNA Translation: AAK56101.1
AF332074 mRNA Translation: AAK56102.1
AY176046 Genomic DNA Translation: AAN75014.1
AK049203 mRNA Translation: BAC33607.2
AK054437 mRNA Translation: BAC35779.2
AK147199 mRNA Translation: BAE27757.1
AL591205 Genomic DNA Translation: CAM21264.1
AL591205 Genomic DNA Translation: CAM21266.1
BC021440 mRNA Translation: AAH21440.1 Different initiation.
BC079636 mRNA Translation: AAH79636.1
CCDSiCCDS25341.1 [Q925J9-4]
CCDS36300.1 [Q925J9-1]
PIRiT02885
RefSeqiNP_001073587.1, NM_001080118.1 [Q925J9-1]
NP_038662.2, NM_013634.2 [Q925J9-4]
NP_598788.2, NM_134027.2 [Q925J9-3]
UniGeneiMm.12926

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XDKX-ray2.90C/D/G/H641-654[»]
ProteinModelPortaliQ925J9
SMRiQ925J9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202318, 5 interactors
ComplexPortaliCPX-3264 Core mediator complex
CORUMiQ925J9
DIPiDIP-59232N
ELMiQ925J9
IntActiQ925J9, 10 interactors
MINTiQ925J9
STRINGi10090.ENSMUSP00000103169

PTM databases

iPTMnetiQ925J9
PhosphoSitePlusiQ925J9

Proteomic databases

EPDiQ925J9
PaxDbiQ925J9
PeptideAtlasiQ925J9
PRIDEiQ925J9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000018304; ENSMUSP00000018304; ENSMUSG00000018160 [Q925J9-4]
ENSMUST00000107545; ENSMUSP00000103169; ENSMUSG00000018160 [Q925J9-1]
GeneIDi19014
KEGGimmu:19014
UCSCiuc007lfo.1 mouse [Q925J9-3]
uc007lfp.1 mouse [Q925J9-1]

Organism-specific databases

CTDi5469
MGIiMGI:1100846 Med1

Phylogenomic databases

eggNOGiENOG410IEFR Eukaryota
ENOG410XR2E LUCA
GeneTreeiENSGT00660000095569
HOVERGENiHBG101127
InParanoidiQ925J9
KOiK15144
OMAiHPMLMNL
OrthoDBiEOG091G035E
PhylomeDBiQ925J9
TreeFamiTF324954

Enzyme and pathway databases

ReactomeiR-MMU-212436 Generic Transcription Pathway
R-MMU-383280 Nuclear Receptor transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-9018519 Estrogen-dependent gene expression

Miscellaneous databases

EvolutionaryTraceiQ925J9
PROiPR:Q925J9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018160 Expressed in 296 organ(s), highest expression level in rostral migratory stream
CleanExiMM_MED1
ExpressionAtlasiQ925J9 baseline and differential
GenevisibleiQ925J9 MM

Family and domain databases

InterProiView protein in InterPro
IPR019680 Mediator_Med1
PfamiView protein in Pfam
PF10744 Med1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMED1_MOUSE
AccessioniPrimary (citable) accession number: Q925J9
Secondary accession number(s): A2A526
, A2A528, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: September 12, 2018
This is version 146 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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