UniProtKB - Q924Z6 (XPO6_MOUSE)

BLAST

>sp|Q924Z6|XPO6_MOUSE Exportin-6 OS=Mus musculus OX=10090 GN=Xpo6 PE=1 SV=2
MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQVGAWRFCLYFLSSTRNDYV
MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLHQPIPILDV
ESEYVCSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDTRARKMASVNGSSQNCV
LGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGSGHRLN
ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCGEAHRQNTQQFVTLISTTMDA
ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNSIIDASAQRLTDKAQV
LVCRALSNTLLLPWPNLPESEQQWPLRSINHASLISALSRDYHSLKPSATAPQRKVPLGD
TKVIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLS
FFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVV
QEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLA
SVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRT
TMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQ
KNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL

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History
Entry version 111 (10 Oct 2018)
Sequence version 2 (16 May 2006)
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Protein

Exportin-6

Gene

Xpo6

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.1 Publication

GO - Molecular functionⁱ

protein transporter activity Source: MGI
Ran GTPase binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

protein export from nucleus Source: MGI

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Protein transport, Transport

Biological process

Protein transport, Transport

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Exportin-6 Short name: Exp6 Alternative name(s): Ran-binding protein 20
Gene namesⁱ	Name:Xpo6 Synonyms:Ranbp20
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 7

Organism-specific databases

MGIⁱ	MGI:2429950 Xpo6

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		RemovedBy similarity
ChainⁱPRO_0000235302	2 – 1125	Exportin-6Add BLAST		1124

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	2	N-acetylalanineBy similarity	1
Modified residueⁱ	199	PhosphoserineCombined sources	1
Modified residueⁱ	201	PhosphothreonineCombined sources	1
Modified residueⁱ	204	PhosphothreonineCombined sources	1
Modified residueⁱ	208	PhosphoserineCombined sources	1
Modified residueⁱ	224	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

PaxDbⁱ	Q924Z6
PeptideAtlas More...PeptideAtlasⁱ	Q924Z6
PRIDEⁱ	Q924Z6

PTM databases

iPTMnetⁱ	Q924Z6
PhosphoSitePlusⁱ	Q924Z6

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000000131 Expressed in 290 organ(s), highest expression level in cerebral cortex
CleanExⁱ	MM_XPO6
ExpressionAtlasⁱ	Q924Z6 baseline and differential
Genevisibleⁱ	Q924Z6 MM

Interactionⁱ

Subunit structureⁱ

Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with ACTB. Interacts with ACTB in a RanGTP-dependent manner.By similarity

GO - Molecular functionⁱ

Ran GTPase binding Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000009344

STRINGⁱ

10090.ENSMUSP00000009344

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	31 – 97	Importin N-terminalPROSITE-ProRule annotationAdd BLAST		67

Sequence similaritiesⁱ

Belongs to the exportin family.Curated

Phylogenomic databases

eggNOGⁱ	KOG2020 Eukaryota COG5101 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000002810
HOGENOMⁱ	HOG000220888
HOVERGENⁱ	HBG054104
InParanoidⁱ	Q924Z6
OMAⁱ	WQRYLRQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G040W
PhylomeDBⁱ	Q924Z6
TreeFamⁱ	TF323443

Family and domain databases

Gene3Dⁱ	1.25.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR011989 ARM-like IPR016024 ARM-type_fold IPR013598 Exportin-1/Importin-b-like IPR001494 Importin-beta_N
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03810 IBN_N, 1 hit PF08389 Xpo1, 1 hit
SMARTⁱ	View protein in SMART SM00913 IBN_N, 1 hit
SUPFAMⁱ	SSF48371 SSF48371, 5 hits
PROSITEⁱ	View protein in PROSITE PS50166 IMPORTIN_B_NT, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 10 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q924Z6-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASEEASLRA LESLMTEFFH DCTTNERKRE IEELLNNFAQ QVGAWRFCLY 
        60         70         80         90        100
FLSSTRNDYV MMYSLTVFEN LINKMWLGVP SQDKMEIRSC LPKLLLAHHK 
       110        120        130        140        150
TLPYFIRNKL CKVIVDIGRQ DWPMFYHDFF TNILQLIQSP VTTPLGLIML 
       160        170        180        190        200
KTTSEELACP REDLSVARKE ELRKLLLDQV QTVLGLLTGI LETVWDKHSV 
       210        220        230        240        250
TAATPPPSPT SGESGDLLSN LLQSPSSAKL LHQPIPILDV ESEYVCSLAL 
       260        270        280        290        300
ECLAHLFSWI PLSASITPSL LTTIFHFARF GCDTRARKMA SVNGSSQNCV 
       310        320        330        340        350
LGQERGRLGV LAMSCINELM SKNCVPMEFE EYLLRMFQQT FYLLQKITKD 
       360        370        380        390        400
NNAHTVKSRL EELDESYIEK FTDFLRLFVS VHLRRIESYS QFPVVEFLTL 
       410        420        430        440        450
LFKYTFHQPT HEGYFSCLDI WTLFLDYLTS KIKSRLGDKE AVLNRYEDAL 
       460        470        480        490        500
VLLLTEVLNR IQFRYNQAQL EELDDETLDD DQQTEWQRYL RQSLEVVAKV 
       510        520        530        540        550
MELLPTHAFS TLFPVLQDNL EVYLGLQQFV VTSGSGHRLN ITAENDCRRL 
       560        570        580        590        600
HCSLRDLSSL LQAVGRLAEY FIGDVFAARF NDALTVVERL VKVTLYGSQI 
       610        620        630        640        650
KLYNIETAVP SVLKPDLIDV HAQSLAALQA YSHWLAQYCG EAHRQNTQQF 
       660        670        680        690        700
VTLISTTMDA ITPLISTKVQ DKLLLSACHL LVSLATTVRP VFLISIPAVQ 
       710        720        730        740        750
KVFNSIIDAS AQRLTDKAQV LVCRALSNTL LLPWPNLPES EQQWPLRSIN 
       760        770        780        790        800
HASLISALSR DYHSLKPSAT APQRKVPLGD TKVIIHQTLS VLEDIVENIS 
       810        820        830        840        850
GESTKSRQIC YQSLQESVQV SLALFPAFIH QSDVTDEMLS FFLTLFRGLR 
       860        870        880        890        900
VQMGVPFTEQ IIQTFLNMFT REQLAESILH EGSTGCRVVE KFLKILQVVV 
       910        920        930        940        950
QEPGQVFKPF LPSIIALCME QVYPIIAERP SPDVKAELFE LLFRTLHHNW 
       960        970        980        990       1000
RYFFKSTVLA SVQRGIAEEQ MENEPQFSAI MQAFGQSFLQ PDIHLFKQNL 
      1010       1020       1030       1040       1050
FYLETLNTKQ KLYHKKIFRT TMLFQFVNVL LQVLVHKSHD LLQEEIGIAI 
      1060       1070       1080       1090       1100
YNMASVDFDG FFAAFLPEFL TSCDGVDANQ KNVLGRNFKM DRDLPSFTQN 
      1110       1120 
VHRLVNDLRY YRLCNDSLPP GTVKL

Length:1,125

Mass (Da):128,664

Last modified:May 16, 2006 - v2

Checksum:ⁱCA808BDB172A84B9

Isoform 2 (identifier: Q924Z6-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
482-482: Missing.

« Hide

        10         20         30         40         50
MASEEASLRA LESLMTEFFH DCTTNERKRE IEELLNNFAQ QVGAWRFCLY 
        60         70         80         90        100
FLSSTRNDYV MMYSLTVFEN LINKMWLGVP SQDKMEIRSC LPKLLLAHHK 
       110        120        130        140        150
TLPYFIRNKL CKVIVDIGRQ DWPMFYHDFF TNILQLIQSP VTTPLGLIML 
       160        170        180        190        200
KTTSEELACP REDLSVARKE ELRKLLLDQV QTVLGLLTGI LETVWDKHSV 
       210        220        230        240        250
TAATPPPSPT SGESGDLLSN LLQSPSSAKL LHQPIPILDV ESEYVCSLAL 
       260        270        280        290        300
ECLAHLFSWI PLSASITPSL LTTIFHFARF GCDTRARKMA SVNGSSQNCV 
       310        320        330        340        350
LGQERGRLGV LAMSCINELM SKNCVPMEFE EYLLRMFQQT FYLLQKITKD 
       360        370        380        390        400
NNAHTVKSRL EELDESYIEK FTDFLRLFVS VHLRRIESYS QFPVVEFLTL 
       410        420        430        440        450
LFKYTFHQPT HEGYFSCLDI WTLFLDYLTS KIKSRLGDKE AVLNRYEDAL 
       460        470        480        490        500
VLLLTEVLNR IQFRYNQAQL EELDDETLDD DQTEWQRYLR QSLEVVAKVM 
       510        520        530        540        550
ELLPTHAFST LFPVLQDNLE VYLGLQQFVV TSGSGHRLNI TAENDCRRLH 
       560        570        580        590        600
CSLRDLSSLL QAVGRLAEYF IGDVFAARFN DALTVVERLV KVTLYGSQIK 
       610        620        630        640        650
LYNIETAVPS VLKPDLIDVH AQSLAALQAY SHWLAQYCGE AHRQNTQQFV 
       660        670        680        690        700
TLISTTMDAI TPLISTKVQD KLLLSACHLL VSLATTVRPV FLISIPAVQK 
       710        720        730        740        750
VFNSIIDASA QRLTDKAQVL VCRALSNTLL LPWPNLPESE QQWPLRSINH 
       760        770        780        790        800
ASLISALSRD YHSLKPSATA PQRKVPLGDT KVIIHQTLSV LEDIVENISG 
       810        820        830        840        850
ESTKSRQICY QSLQESVQVS LALFPAFIHQ SDVTDEMLSF FLTLFRGLRV 
       860        870        880        890        900
QMGVPFTEQI IQTFLNMFTR EQLAESILHE GSTGCRVVEK FLKILQVVVQ 
       910        920        930        940        950
EPGQVFKPFL PSIIALCMEQ VYPIIAERPS PDVKAELFEL LFRTLHHNWR 
       960        970        980        990       1000
YFFKSTVLAS VQRGIAEEQM ENEPQFSAIM QAFGQSFLQP DIHLFKQNLF 
      1010       1020       1030       1040       1050
YLETLNTKQK LYHKKIFRTT MLFQFVNVLL QVLVHKSHDL LQEEIGIAIY 
      1060       1070       1080       1090       1100
NMASVDFDGF FAAFLPEFLT SCDGVDANQK NVLGRNFKMD RDLPSFTQNV 
      1110       1120 
HRLVNDLRYY RLCNDSLPPG TVKL

Note: No experimental confirmation available.

Show »

Length:1,124

Mass (Da):128,536

Checksum:ⁱDDB2EB30BD7A979B

Isoform 3 (identifier: Q924Z6-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-879: Missing.
880-928: HEGSTGCRVV...MEQVYPIIAE → MAQGLLHGKW...RCSVVWISLQ

« Hide

        10         20         30         40         50
MAQGLLHGKW QKCGWDMSTG YCLAPLRLLW WPPPSCMEGR CSVVWISLQR 
        60         70         80         90        100
PSPDVKAELF ELLFRTLHHN WRYFFKSTVL ASVQRGIAEE QMENEPQFSA 
       110        120        130        140        150
IMQAFGQSFL QPDIHLFKQN LFYLETLNTK QKLYHKKIFR TTMLFQFVNV 
       160        170        180        190        200
LLQVLVHKSH DLLQEEIGIA IYNMASVDFD GFFAAFLPEF LTSCDGVDAN 
       210        220        230        240 
QKNVLGRNFK MDRDLPSFTQ NVHRLVNDLR YYRLCNDSLP PGTVKL

Note: No experimental confirmation available.

Show »

Length:246

Mass (Da):28,660

Checksum:ⁱD84691A1141733C7

Computationally mapped potential isoform sequencesⁱ

There are 10 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

F6WSY2	F6WSY2_MOUSE	Exportin-6 Exportin-6	Xpo6	255	Annotation score:
F6Z1I1	F6Z1I1_MOUSE	Exportin-6 Exportin-6	Xpo6	142	Annotation score:
F6Y2I6	F6Y2I6_MOUSE	Exportin-6 Exportin-6	Xpo6	132	Annotation score:
F7B8F0	F7B8F0_MOUSE	Exportin-6 Exportin-6	Xpo6	87	Annotation score:
E9Q081	E9Q081_MOUSE	Exportin-6 Exportin-6	Xpo6	35	Annotation score:
F6ZUE3	F6ZUE3_MOUSE	Exportin-6 Exportin-6	Xpo6	38	Annotation score:
F6XQN1	F6XQN1_MOUSE	Exportin-6 Exportin-6	Xpo6	135	Annotation score:
E9Q6V5	E9Q6V5_MOUSE	Exportin-6 Exportin-6	Xpo6	28	Annotation score:
F6YJ47	F6YJ47_MOUSE	Exportin-6 Exportin-6	Xpo6	71	Annotation score:
F6U927	F6U927_MOUSE	Exportin-6 Exportin-6	Xpo6	65	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	483	Missing in AAH58090 (PubMed:16141072).Curated	1
Sequence conflictⁱ	626	A → S in BAE32778 (PubMed:16141072).Curated	1
Sequence conflictⁱ	1072	S → R in BAE32778 (PubMed:16141072).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_018466	1 – 879	Missing in isoform 3. 1 PublicationAdd BLAST	879
Alternative sequenceⁱVSP_018467	482	Missing in isoform 2. 1 Publication	1
Alternative sequenceⁱVSP_018468	880 – 928	HEGST…PIIAE → MAQGLLHGKWQKCGWDMSTG YCLAPLRLLWWPPPSCMEGR CSVVWISLQ in isoform 3. 1 PublicationAdd BLAST	49

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY029528 mRNA Translation: AAK40296.1 AK011324 mRNA Translation: BAB27545.1 AK154709 mRNA Translation: BAE32778.1 BC058090 mRNA Translation: AAH58090.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS52396.1 [Q924Z6-2] CCDS80800.1 [Q924Z6-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001298072.1, NM_001311143.1 [Q924Z6-1] NP_083092.2, NM_028816.2 [Q924Z6-2]
UniGeneⁱ	Mm.235663

Genome annotation databases

Ensemblⁱ	ENSMUST00000009344; ENSMUSP00000009344; ENSMUSG00000000131 [Q924Z6-2] ENSMUST00000168189; ENSMUSP00000130527; ENSMUSG00000000131 [Q924Z6-1]
GeneIDⁱ	74204
KEGGⁱ	mmu:74204
UCSC genome browser More...UCSCⁱ	uc009jqq.1 mouse [Q924Z6-1] uc009jqr.1 mouse [Q924Z6-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q924Z6	Exportin-6		HUMAN		1125	UniRef90_Q96QU8
XPO6 isoform 2		PONAB		1125
Exportin-6		MYODS		1156
Uncharacterized protein		MUSPF		1146
Uncharacterized protein		CHICK		1145
+340

Protein	Similar proteins		Species	Score	Length	Source
Q924Z6	Exportin-6		HUMAN		1125	UniRef50_Q96QU8
Exportin-6		DANRE		1128
Exportin-6-B		XENLA		1138
XPO6 isoform 2		PONAB		1125
Exportin-6		MYODS		1156
+602
Q924Z6-3	Putative exportin-6-b (Fragment)		western dwarf clawed frog		238	UniRef50_Q924Z6-3

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY029528 mRNA Translation: AAK40296.1 AK011324 mRNA Translation: BAB27545.1 AK154709 mRNA Translation: BAE32778.1 BC058090 mRNA Translation: AAH58090.1
CCDSⁱ	CCDS52396.1 [Q924Z6-2] CCDS80800.1 [Q924Z6-1]
RefSeqⁱ	NP_001298072.1, NM_001311143.1 [Q924Z6-1] NP_083092.2, NM_028816.2 [Q924Z6-2]
UniGeneⁱ	Mm.235663

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000009344

STRINGⁱ

10090.ENSMUSP00000009344

PTM databases

iPTMnetⁱ	Q924Z6
PhosphoSitePlusⁱ	Q924Z6

Proteomic databases

PaxDbⁱ	Q924Z6
PeptideAtlasⁱ	Q924Z6
PRIDEⁱ	Q924Z6

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000009344; ENSMUSP00000009344; ENSMUSG00000000131 [Q924Z6-2] ENSMUST00000168189; ENSMUSP00000130527; ENSMUSG00000000131 [Q924Z6-1]
GeneIDⁱ	74204
KEGGⁱ	mmu:74204
UCSCⁱ	uc009jqq.1 mouse [Q924Z6-1] uc009jqr.1 mouse [Q924Z6-2]

Organism-specific databases

CTDⁱ	23214
MGIⁱ	MGI:2429950 Xpo6

Phylogenomic databases

eggNOGⁱ	KOG2020 Eukaryota COG5101 LUCA
GeneTreeⁱ	ENSGT00390000002810
HOGENOMⁱ	HOG000220888
HOVERGENⁱ	HBG054104
InParanoidⁱ	Q924Z6
OMAⁱ	WQRYLRQ
OrthoDBⁱ	EOG091G040W
PhylomeDBⁱ	Q924Z6
TreeFamⁱ	TF323443

Miscellaneous databases

ChiTaRSⁱ	Xpo6 mouse
Protein Ontology More...PROⁱ	PR:Q924Z6
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000000131 Expressed in 290 organ(s), highest expression level in cerebral cortex
CleanExⁱ	MM_XPO6
ExpressionAtlasⁱ	Q924Z6 baseline and differential
Genevisibleⁱ	Q924Z6 MM

Family and domain databases

Gene3Dⁱ	1.25.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR011989 ARM-like IPR016024 ARM-type_fold IPR013598 Exportin-1/Importin-b-like IPR001494 Importin-beta_N
Pfamⁱ	View protein in Pfam PF03810 IBN_N, 1 hit PF08389 Xpo1, 1 hit
SMARTⁱ	View protein in SMART SM00913 IBN_N, 1 hit
SUPFAMⁱ	SSF48371 SSF48371, 5 hits
PROSITEⁱ	View protein in PROSITE PS50166 IMPORTIN_B_NT, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	XPO6_MOUSE
Accessionⁱ	Q924Z6Primary (citable) accession number: Q924Z6 Secondary accession number(s): Q3U3K7, Q6PEF3, Q9D0K9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
	Last sequence update:	May 16, 2006
	Last modified:	October 10, 2018
	This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q924Z6 (XPO6_MOUSE)

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Exportin-6

Xpo6

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Cytosol

Nucleus

Plasma Membrane

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

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<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ