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Protein

28S ribosomal protein S2, mitochondrial

Gene

Mrps2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for mitoribosome formation and stability, and mitochondrial translation.By similarity

GO - Molecular functioni

  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S2, mitochondrial
Short name:
MRP-S2
Short name:
S2mt
Gene namesi
Name:Mrps2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2153089 Mrps2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001343441 – 29128S ribosomal protein S2, mitochondrialAdd BLAST291

Proteomic databases

EPDiQ924T2
MaxQBiQ924T2
PaxDbiQ924T2
PeptideAtlasiQ924T2
PRIDEiQ924T2

PTM databases

iPTMnetiQ924T2
PhosphoSitePlusiQ924T2

Expressioni

Gene expression databases

BgeeiENSMUSG00000035772 Expressed in 287 organ(s), highest expression level in primitive streak
CleanExiMM_MRPS2
GenevisibleiQ924T2 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036725

Structurei

3D structure databases

ProteinModelPortaliQ924T2
SMRiQ924T2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0832 Eukaryota
COG0052 LUCA
GeneTreeiENSGT00390000017382
HOGENOMiHOG000071892
HOVERGENiHBG028633
InParanoidiQ924T2
KOiK02967
OMAiSYIDRAY
OrthoDBiEOG091G0NYD
PhylomeDBiQ924T2
TreeFamiTF313480

Family and domain databases

CDDicd01425 RPS2, 1 hit
HAMAPiMF_00291_B Ribosomal_S2_B, 1 hit
InterProiView protein in InterPro
IPR001865 Ribosomal_S2
IPR005706 Ribosomal_S2_bac/mit/plastid
IPR018130 Ribosomal_S2_CS
IPR023591 Ribosomal_S2_flav_dom_sf
PANTHERiPTHR12534 PTHR12534, 1 hit
PfamiView protein in Pfam
PF00318 Ribosomal_S2, 2 hits
PRINTSiPR00395 RIBOSOMALS2
SUPFAMiSSF52313 SSF52313, 1 hit
PROSITEiView protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q924T2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPAPAVLTR LLCAGVRRWP GFLQKAIPGP AEQNGRKVTG APVPAVSEPQ
60 70 80 90 100
DGDDFQSRIL DTPLQHSDFF NVKELFSVKS LFEARVHLGH KAGCRHRFME
110 120 130 140 150
PYIFGNRLGQ DIIDLDQTAL NLQLALNFTA HVAYRKGIIL FVSRNRQFSH
160 170 180 190 200
LIETTAQACG EYAHTRYFKG GLLTNAQLLF GPSVRLPDLI IFLHTLNNVF
210 220 230 240 250
EPHVAVRDAA KMNIPTVGIV DTNCNPCLIT YPIPGNDDSP QAIQLFCKLF
260 270 280 290
RTTINRAKEK RRQMEALHRL QSPKGSEGSG TSPVPDKSHS P
Length:291
Mass (Da):32,313
Last modified:December 1, 2001 - v1
Checksum:i33CFE4731BCEBADD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055389 mRNA Translation: BAB62530.1
AK077219 mRNA Translation: BAC36691.1
AK154131 mRNA Translation: BAE32396.1
AK165956 mRNA Translation: BAE38484.1
AL772249 Genomic DNA No translation available.
BC060503 mRNA Translation: AAH60503.1
CCDSiCCDS15838.1
RefSeqiNP_001159503.2, NM_001166031.2
NP_536700.3, NM_080452.3
UniGeneiMm.294951

Genome annotation databases

EnsembliENSMUST00000038600; ENSMUSP00000036725; ENSMUSG00000035772
GeneIDi118451
KEGGimmu:118451
UCSCiuc008iyg.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055389 mRNA Translation: BAB62530.1
AK077219 mRNA Translation: BAC36691.1
AK154131 mRNA Translation: BAE32396.1
AK165956 mRNA Translation: BAE38484.1
AL772249 Genomic DNA No translation available.
BC060503 mRNA Translation: AAH60503.1
CCDSiCCDS15838.1
RefSeqiNP_001159503.2, NM_001166031.2
NP_536700.3, NM_080452.3
UniGeneiMm.294951

3D structure databases

ProteinModelPortaliQ924T2
SMRiQ924T2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036725

PTM databases

iPTMnetiQ924T2
PhosphoSitePlusiQ924T2

Proteomic databases

EPDiQ924T2
MaxQBiQ924T2
PaxDbiQ924T2
PeptideAtlasiQ924T2
PRIDEiQ924T2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038600; ENSMUSP00000036725; ENSMUSG00000035772
GeneIDi118451
KEGGimmu:118451
UCSCiuc008iyg.1 mouse

Organism-specific databases

CTDi51116
MGIiMGI:2153089 Mrps2

Phylogenomic databases

eggNOGiKOG0832 Eukaryota
COG0052 LUCA
GeneTreeiENSGT00390000017382
HOGENOMiHOG000071892
HOVERGENiHBG028633
InParanoidiQ924T2
KOiK02967
OMAiSYIDRAY
OrthoDBiEOG091G0NYD
PhylomeDBiQ924T2
TreeFamiTF313480

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRSiMrps2 mouse
PROiPR:Q924T2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035772 Expressed in 287 organ(s), highest expression level in primitive streak
CleanExiMM_MRPS2
GenevisibleiQ924T2 MM

Family and domain databases

CDDicd01425 RPS2, 1 hit
HAMAPiMF_00291_B Ribosomal_S2_B, 1 hit
InterProiView protein in InterPro
IPR001865 Ribosomal_S2
IPR005706 Ribosomal_S2_bac/mit/plastid
IPR018130 Ribosomal_S2_CS
IPR023591 Ribosomal_S2_flav_dom_sf
PANTHERiPTHR12534 PTHR12534, 1 hit
PfamiView protein in Pfam
PF00318 Ribosomal_S2, 2 hits
PRINTSiPR00395 RIBOSOMALS2
SUPFAMiSSF52313 SSF52313, 1 hit
PROSITEiView protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT02_MOUSE
AccessioniPrimary (citable) accession number: Q924T2
Secondary accession number(s): A2AK29, Q3TMF8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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