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Entry version 127 (18 Sep 2019)
Sequence version 1 (01 Dec 2001)
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Protein

28S ribosomal protein S2, mitochondrial

Gene

Mrps2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for mitoribosome formation and stability, and mitochondrial translation.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
28S ribosomal protein S2, mitochondrial
Short name:
MRP-S2
Short name:
S2mt
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mrps2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2153089 Mrps2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001343441 – 29128S ribosomal protein S2, mitochondrialAdd BLAST291

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q924T2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q924T2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q924T2

PeptideAtlas

More...
PeptideAtlasi
Q924T2

PRoteomics IDEntifications database

More...
PRIDEi
Q924T2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q924T2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q924T2

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q924T2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035772 Expressed in 287 organ(s), highest expression level in primitive streak

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q924T2 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
228246, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000036725

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q924T2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0832 Eukaryota
COG0052 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017382

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000071892

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q924T2

KEGG Orthology (KO)

More...
KOi
K02967

Identification of Orthologs from Complete Genome Data

More...
OMAi
SYIDRAY

Database of Orthologous Groups

More...
OrthoDBi
573006at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q924T2

TreeFam database of animal gene trees

More...
TreeFami
TF313480

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01425 RPS2, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00291_B Ribosomal_S2_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001865 Ribosomal_S2
IPR005706 Ribosomal_S2_bac/mit/plastid
IPR018130 Ribosomal_S2_CS
IPR023591 Ribosomal_S2_flav_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12534 PTHR12534, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00318 Ribosomal_S2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00395 RIBOSOMALS2

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52313 SSF52313, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q924T2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPAPAVLTR LLCAGVRRWP GFLQKAIPGP AEQNGRKVTG APVPAVSEPQ
60 70 80 90 100
DGDDFQSRIL DTPLQHSDFF NVKELFSVKS LFEARVHLGH KAGCRHRFME
110 120 130 140 150
PYIFGNRLGQ DIIDLDQTAL NLQLALNFTA HVAYRKGIIL FVSRNRQFSH
160 170 180 190 200
LIETTAQACG EYAHTRYFKG GLLTNAQLLF GPSVRLPDLI IFLHTLNNVF
210 220 230 240 250
EPHVAVRDAA KMNIPTVGIV DTNCNPCLIT YPIPGNDDSP QAIQLFCKLF
260 270 280 290
RTTINRAKEK RRQMEALHRL QSPKGSEGSG TSPVPDKSHS P
Length:291
Mass (Da):32,313
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i33CFE4731BCEBADD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB055389 mRNA Translation: BAB62530.1
AK077219 mRNA Translation: BAC36691.1
AK154131 mRNA Translation: BAE32396.1
AK165956 mRNA Translation: BAE38484.1
AL772249 Genomic DNA No translation available.
BC060503 mRNA Translation: AAH60503.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15838.1

NCBI Reference Sequences

More...
RefSeqi
NP_001159503.2, NM_001166031.2
NP_536700.3, NM_080452.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000038600; ENSMUSP00000036725; ENSMUSG00000035772

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
118451

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:118451

UCSC genome browser

More...
UCSCi
uc008iyg.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055389 mRNA Translation: BAB62530.1
AK077219 mRNA Translation: BAC36691.1
AK154131 mRNA Translation: BAE32396.1
AK165956 mRNA Translation: BAE38484.1
AL772249 Genomic DNA No translation available.
BC060503 mRNA Translation: AAH60503.1
CCDSiCCDS15838.1
RefSeqiNP_001159503.2, NM_001166031.2
NP_536700.3, NM_080452.3

3D structure databases

SMRiQ924T2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi228246, 1 interactor
STRINGi10090.ENSMUSP00000036725

PTM databases

iPTMnetiQ924T2
PhosphoSitePlusiQ924T2
SwissPalmiQ924T2

Proteomic databases

EPDiQ924T2
MaxQBiQ924T2
PaxDbiQ924T2
PeptideAtlasiQ924T2
PRIDEiQ924T2

Genome annotation databases

EnsembliENSMUST00000038600; ENSMUSP00000036725; ENSMUSG00000035772
GeneIDi118451
KEGGimmu:118451
UCSCiuc008iyg.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51116
MGIiMGI:2153089 Mrps2

Phylogenomic databases

eggNOGiKOG0832 Eukaryota
COG0052 LUCA
GeneTreeiENSGT00390000017382
HOGENOMiHOG000071892
InParanoidiQ924T2
KOiK02967
OMAiSYIDRAY
OrthoDBi573006at2759
PhylomeDBiQ924T2
TreeFamiTF313480

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Mrps2 mouse

Protein Ontology

More...
PROi
PR:Q924T2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035772 Expressed in 287 organ(s), highest expression level in primitive streak
GenevisibleiQ924T2 MM

Family and domain databases

CDDicd01425 RPS2, 1 hit
HAMAPiMF_00291_B Ribosomal_S2_B, 1 hit
InterProiView protein in InterPro
IPR001865 Ribosomal_S2
IPR005706 Ribosomal_S2_bac/mit/plastid
IPR018130 Ribosomal_S2_CS
IPR023591 Ribosomal_S2_flav_dom_sf
PANTHERiPTHR12534 PTHR12534, 1 hit
PfamiView protein in Pfam
PF00318 Ribosomal_S2, 2 hits
PRINTSiPR00395 RIBOSOMALS2
SUPFAMiSSF52313 SSF52313, 1 hit
PROSITEiView protein in PROSITE
PS00962 RIBOSOMAL_S2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRT02_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q924T2
Secondary accession number(s): A2AK29, Q3TMF8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: December 1, 2001
Last modified: September 18, 2019
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
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