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UniProtKB - Q92367 (AAP1_SCHPO)
Protein
Amino-acid permease 1
Gene
aap1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: PomBase
- mechanosensitive cation channel activity Source: PomBase
GO - Biological processi
- amino acid transmembrane transport Source: PomBase
Keywordsi
Biological process | Amino-acid transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Amino-acid permease 1 |
Gene namesi | Name:aap1 ORF Names:SPBC1652.02, SPBC16A3.20c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC1652.02 |
VEuPathDBi | FungiDB:SPBC1652.02 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
Plasma Membrane
- plasma membrane Source: PomBase
Vacuole
- fungal-type vacuole Source: PomBase
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 75 – 95 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 101 – 121 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 146 – 166 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 181 – 201 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 210 – 230 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 297 – 317 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 323 – 343 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 344 – 364 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 390 – 410 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 416 – 436 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 468 – 488 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 498 – 518 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054166 | 1 – 594 | Amino-acid permease 1Add BLAST | 594 |
Proteomic databases
MaxQBi | Q92367 |
PaxDbi | Q92367 |
PTM databases
iPTMneti | Q92367 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 276698, 1 interactor |
STRINGi | 4896.SPBC1652.02.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 550 – 587 | DisorderedSequence analysisAdd BLAST | 38 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 550 – 584 | Polar residuesSequence analysisAdd BLAST | 35 |
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | Q92367 |
OMAi | QGWAPRF |
PhylomeDBi | Q92367 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q92367-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTSFTESKKL DEIESPVPEI IVPSTTNGNG TIESYKEKSV GTSFLDFFRS
60 70 80 90 100
YKLRPDNEFA EVHNSEDFLK PRHLQMIAIG SCIGTGLFVS TGKSLKNAGP
110 120 130 140 150
GSLMINFIIL SAMILALILS LGEMCCFLPN QSSITMYTGR LLNNNIGFAQ
160 170 180 190 200
SWLYFWIWLT VLPSEISAAC EVVDFWTTQH LNPAIWVTIF LAYVVLVNAF
210 220 230 240 250
GARSYGECEF VSSFLKVVIV IIFFFVAIII NCGAAPKGGY IGAHYWHHPG
260 270 280 290 300
SFRNGFKGFC SVFISSAYSL SGTENIGTAA GNTSNPQRAI PSAVKKVFYR
310 320 330 340 350
MGFFYIITIF LITLVVPYDN PDLGNVSPFI IAIKNGGIHV LPHITNAVIL
360 370 380 390 400
VSVLSVGNAA VFAASRNAMA LVKQGWAPRF LGRVDQKGRP VISYLCSLAM
410 420 430 440 450
ACIAYVNAAP DGSVVFDWLM SVSGGGAFVI WGLSFIDHIR LRYAMKAQKI
460 470 480 490 500
PDTVLPYKFP GSVYLSYYGV LINFLALCAL VYISIFPVTH EKPSAYGFFV
510 520 530 540 550
SFLGPSVFIA YLLISPIFVK PTFQSLKDVD LTTGRYDLVN SQMYVAESST
560 570 580 590
SELSEKDLTK PNLQSNDNKN SEDLESNTPP QKKSALQKVA DFLC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D87954 Genomic DNA Translation: BAA13506.1 CU329671 Genomic DNA Translation: CAB86887.1 AB028013 Genomic DNA Translation: BAA87317.1 |
PIRi | T43246 |
RefSeqi | NP_596769.2, NM_001023790.3 |
Genome annotation databases
EnsemblFungii | SPBC1652.02.1; SPBC1652.02.1:pep; SPBC1652.02 |
GeneIDi | 2540163 |
KEGGi | spo:SPBC1652.02 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D87954 Genomic DNA Translation: BAA13506.1 CU329671 Genomic DNA Translation: CAB86887.1 AB028013 Genomic DNA Translation: BAA87317.1 |
PIRi | T43246 |
RefSeqi | NP_596769.2, NM_001023790.3 |
3D structure databases
SMRi | Q92367 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 276698, 1 interactor |
STRINGi | 4896.SPBC1652.02.1 |
PTM databases
iPTMneti | Q92367 |
Proteomic databases
MaxQBi | Q92367 |
PaxDbi | Q92367 |
Genome annotation databases
EnsemblFungii | SPBC1652.02.1; SPBC1652.02.1:pep; SPBC1652.02 |
GeneIDi | 2540163 |
KEGGi | spo:SPBC1652.02 |
Organism-specific databases
PomBasei | SPBC1652.02 |
VEuPathDBi | FungiDB:SPBC1652.02 |
Phylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | Q92367 |
OMAi | QGWAPRF |
PhylomeDBi | Q92367 |
Miscellaneous databases
PROi | PR:Q92367 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AAP1_SCHPO | |
Accessioni | Q92367Primary (citable) accession number: Q92367 Secondary accession number(s): Q9P7A9, Q9UTT7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 14, 2001 |
Last sequence update: | February 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 148 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families