Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Secreted and transmembrane protein 1A

Gene

Sectm1a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Secreted and transmembrane protein 1A
Gene namesi
Name:Sectm1aImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2384805 Sectm1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 165ExtracellularSequence analysisAdd BLAST138
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Topological domaini187 – 192CytoplasmicSequence analysis6

Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000027126428 – 192Secreted and transmembrane protein 1ASequence analysisAdd BLAST165

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi29N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi55N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi84N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi127N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ921W8
PeptideAtlasiQ921W8
PRIDEiQ921W8

PTM databases

PhosphoSitePlusiQ921W8

Expressioni

Gene expression databases

CleanExiMM_SECTM1A

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026162

Structurei

3D structure databases

ProteinModelPortaliQ921W8
SMRiQ921W8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SECTM family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JFYD Eukaryota
ENOG411174Z LUCA
HOGENOMiHOG000231222
HOVERGENiHBG061092
InParanoidiQ921W8
PhylomeDBiQ921W8

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR033231 SECTM1
PANTHERiPTHR15123 PTHR15123, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q921W8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMTCPSVPAI PTLWLFSILL LVVSLNAQNK SWDNPICTEG ILSVPRGNPA
60 70 80 90 100
VMTCNISNTF TDVTIQLSAN GKDKTIFDKK PQGNFSWRGW ELQVQGGQAQ
110 120 130 140 150
LVIKDTQDDH TGIYLWQLHG RQRCYKNITL NILEPSNEDK VPDTTLFTSF
160 170 180 190
PDHAKSSPIE GKPGTLVGVI TVIFILGVAG FITFIYYRHR RS
Length:192
Mass (Da):21,438
Last modified:December 1, 2001 - v1
Checksum:i13D8989D3F07AE1F
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2ABP9A2ABP9_MOUSE
Secreted and transmembrane protein ...
Sectm1a BC010462, mCG_2143
192Annotation score:
A2ABP7A2ABP7_MOUSE
Secreted and transmembrane protein ...
Sectm1a BC010462, mCG_2143
174Annotation score:
A2ABP8A2ABP8_MOUSE
Secreted and transmembrane protein ...
Sectm1a
89Annotation score:
Q3TBH1Q3TBH1_MOUSE
Secreted and transmembrane protein ...
Sectm1a BC010462, mCG_2143
65Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC010462 mRNA Translation: AAH10462.1
CCDSiCCDS25766.1
UniGeneiMm.69553

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC010462 mRNA Translation: AAH10462.1
CCDSiCCDS25766.1
UniGeneiMm.69553

3D structure databases

ProteinModelPortaliQ921W8
SMRiQ921W8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026162

PTM databases

PhosphoSitePlusiQ921W8

Proteomic databases

PaxDbiQ921W8
PeptideAtlasiQ921W8
PRIDEiQ921W8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:2384805 Sectm1a

Phylogenomic databases

eggNOGiENOG410JFYD Eukaryota
ENOG411174Z LUCA
HOGENOMiHOG000231222
HOVERGENiHBG061092
InParanoidiQ921W8
PhylomeDBiQ921W8

Miscellaneous databases

PROiPR:Q921W8
SOURCEiSearch...

Gene expression databases

CleanExiMM_SECTM1A

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR033231 SECTM1
PANTHERiPTHR15123 PTHR15123, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSCT1A_MOUSE
AccessioniPrimary (citable) accession number: Q921W8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again