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Protein

Metallophosphoesterase domain-containing protein 1

Gene

Mpped1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May have metallophosphoesterase activity (in vitro).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Metallophosphoesterase domain-containing protein 1 (EC:3.1.-.-)
Gene namesi
Name:Mpped1
Synonyms:D15Bwg0669e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:106316 Mpped1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000534041 – 326Metallophosphoesterase domain-containing protein 1Add BLAST326

Proteomic databases

MaxQBiQ91ZG2
PaxDbiQ91ZG2
PRIDEiQ91ZG2

PTM databases

iPTMnetiQ91ZG2
PhosphoSitePlusiQ91ZG2

Expressioni

Gene expression databases

BgeeiENSMUSG00000041708 Expressed in 62 organ(s), highest expression level in brain
CleanExiMM_MPPED1
ExpressionAtlasiQ91ZG2 baseline and differential
GenevisibleiQ91ZG2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041981

Structurei

3D structure databases

ProteinModelPortaliQ91ZG2
SMRiQ91ZG2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0046 family.Curated

Phylogenomic databases

eggNOGiKOG3947 Eukaryota
ENOG4111K47 LUCA
GeneTreeiENSGT00390000007681
HOGENOMiHOG000023302
HOVERGENiHBG000008
InParanoidiQ91ZG2
OMAiHEGYGIS
OrthoDBiEOG091G0CE0
PhylomeDBiQ91ZG2
TreeFamiTF314305

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR024201 Calcineurin-like_Pesterase
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF035808 Pdiesterase_Brain_239, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

Q91ZG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWRPRWDPGI LKAEALALLP CGLGMAFSQS HVMASRRHQH GRLIIEVDEY
60 70 80 90 100
SSNPTQAFTF YNINQGRFQP PHVQMVDPVP HDAPKPPGYT RFVCVSDTHS
110 120 130 140 150
RTDPIQMPYG DVLIHAGDFT ELGLPSEVKK FNEWLGSLPY EYKIVIAGNH
160 170 180 190 200
ELTFDQEFMA DLIKQDFYYF PSVSKLKPEN YENVQSLLTN CIYLQDSEVT
210 220 230 240 250
VRGFRIYGSP WQPWFYGWGF NLPRGQALLE KWNLIPEGVD ILITHGPPLG
260 270 280 290 300
FLDWVPKKMQ RVGCVELLNT VQRRVQPRLH VFGHIHEGYG VMADGTTTYV
310 320
NASVCTVNYQ PVNPPIVIDL PTPRNS
Length:326
Mass (Da):37,214
Last modified:December 1, 2001 - v1
Checksum:i1ED68BD4F424BAD9
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PWC1E9PWC1_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
203Annotation score:
F7D2T2F7D2T2_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
154Annotation score:
F7BTE7F7BTE7_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
220Annotation score:
E9Q0C0E9Q0C0_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
168Annotation score:
E9PZI5E9PZI5_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
209Annotation score:
E9PYE1E9PYE1_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
152Annotation score:
F2Z3Z7F2Z3Z7_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
163Annotation score:
E9Q2Q2E9Q2Q2_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
202Annotation score:
B1APX5B1APX5_MOUSE
Metallophosphoesterase domain-conta...
Mpped1
32Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti183N → D in BAE38367 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK048421 mRNA Translation: BAC33331.1
AK158740 mRNA Translation: BAE34636.1
AK165755 mRNA Translation: BAE38367.1
AL513354 Genomic DNA No translation available.
BC057550 mRNA Translation: AAH57550.1
CCDSiCCDS37164.1
RefSeqiNP_766198.1, NM_172610.3
XP_006520880.1, XM_006520817.3
XP_006520881.1, XM_006520818.3
XP_006520882.1, XM_006520819.2
XP_006520883.1, XM_006520820.3
XP_017172062.1, XM_017316573.1
UniGeneiMm.36395

Genome annotation databases

EnsembliENSMUST00000046168; ENSMUSP00000041981; ENSMUSG00000041708
ENSMUST00000109470; ENSMUSP00000105096; ENSMUSG00000041708
GeneIDi223726
KEGGimmu:223726
UCSCiuc007xbk.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK048421 mRNA Translation: BAC33331.1
AK158740 mRNA Translation: BAE34636.1
AK165755 mRNA Translation: BAE38367.1
AL513354 Genomic DNA No translation available.
BC057550 mRNA Translation: AAH57550.1
CCDSiCCDS37164.1
RefSeqiNP_766198.1, NM_172610.3
XP_006520880.1, XM_006520817.3
XP_006520881.1, XM_006520818.3
XP_006520882.1, XM_006520819.2
XP_006520883.1, XM_006520820.3
XP_017172062.1, XM_017316573.1
UniGeneiMm.36395

3D structure databases

ProteinModelPortaliQ91ZG2
SMRiQ91ZG2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041981

PTM databases

iPTMnetiQ91ZG2
PhosphoSitePlusiQ91ZG2

Proteomic databases

MaxQBiQ91ZG2
PaxDbiQ91ZG2
PRIDEiQ91ZG2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000046168; ENSMUSP00000041981; ENSMUSG00000041708
ENSMUST00000109470; ENSMUSP00000105096; ENSMUSG00000041708
GeneIDi223726
KEGGimmu:223726
UCSCiuc007xbk.1 mouse

Organism-specific databases

CTDi758
MGIiMGI:106316 Mpped1

Phylogenomic databases

eggNOGiKOG3947 Eukaryota
ENOG4111K47 LUCA
GeneTreeiENSGT00390000007681
HOGENOMiHOG000023302
HOVERGENiHBG000008
InParanoidiQ91ZG2
OMAiHEGYGIS
OrthoDBiEOG091G0CE0
PhylomeDBiQ91ZG2
TreeFamiTF314305

Miscellaneous databases

ChiTaRSiMpped1 mouse
PROiPR:Q91ZG2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041708 Expressed in 62 organ(s), highest expression level in brain
CleanExiMM_MPPED1
ExpressionAtlasiQ91ZG2 baseline and differential
GenevisibleiQ91ZG2 MM

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR024201 Calcineurin-like_Pesterase
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF035808 Pdiesterase_Brain_239, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMPPD1_MOUSE
AccessioniPrimary (citable) accession number: Q91ZG2
Secondary accession number(s): A6PW09, Q3TMS4, Q3TYC7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 1, 2001
Last modified: September 12, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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