UniProtKB - Q91YU8 (SSF1_MOUSE)
Protein
Suppressor of SWI4 1 homolog
Gene
Ppan
Organism
Mus musculus (Mouse)
Status
Functioni
May have a role in cell growth.By similarity
GO - Molecular functioni
- rRNA binding Source: GO_Central
GO - Biological processi
- regulation of cell growth by extracellular stimulus Source: MGI
- ribosomal large subunit assembly Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Suppressor of SWI4 1 homologShort name: Ssf-1 Alternative name(s): Peter Pan homolog |
Gene namesi | Name:Ppan Synonyms:Ssf1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2178445, Ppan |
Subcellular locationi
Nucleus
- nucleolus By similarity
Nucleus
Other locations
- preribosome, large subunit precursor Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000120258 | 1 – 470 | Suppressor of SWI4 1 homologAdd BLAST | 470 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 238 | PhosphoserineCombined sources | 1 | |
Modified residuei | 240 | PhosphoserineCombined sources | 1 | |
Modified residuei | 362 | PhosphoserineCombined sources | 1 | |
Modified residuei | 441 | N6-acetyllysineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q91YU8 |
jPOSTi | Q91YU8 |
MaxQBi | Q91YU8 |
PaxDbi | Q91YU8 |
PeptideAtlasi | Q91YU8 |
PRIDEi | Q91YU8 |
PTM databases
iPTMneti | Q91YU8 |
PhosphoSitePlusi | Q91YU8 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000004100, Expressed in lung and 69 other tissues |
ExpressionAtlasi | Q91YU8, baseline and differential |
Genevisiblei | Q91YU8, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 231610, 5 interactors |
IntActi | Q91YU8, 1 interactor |
MINTi | Q91YU8 |
STRINGi | 10090.ENSMUSP00000004203 |
Miscellaneous databases
RNActi | Q91YU8, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 292 | BrixPROSITE-ProRule annotationAdd BLAST | 264 |
Phylogenomic databases
eggNOGi | KOG2963, Eukaryota |
GeneTreei | ENSGT00530000064158 |
HOGENOMi | CLU_026936_0_1_1 |
InParanoidi | Q91YU8 |
OMAi | VTHLMLF |
OrthoDBi | 1199197at2759 |
TreeFami | TF318923 |
Family and domain databases
InterProi | View protein in InterPro IPR007109, Brix |
Pfami | View protein in Pfam PF04427, Brix, 1 hit |
SMARTi | View protein in SMART SM00879, Brix, 1 hit |
PROSITEi | View protein in PROSITE PS50833, BRIX, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q91YU8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGQSGRSRHQ KRNRAQAQLR NLESYAAQPH SFVFTRGRAG RNVRQLSLDV
60 70 80 90 100
RRVMEPLTAT RLQVRKKNSL KDCVAVAGPL GVTHFLILTK TDNSVYLKLM
110 120 130 140 150
RLPGGPTLTF QISKYTLIRD VVSSLRRHRM HEQQFNHPPL LVLNSFGPQG
160 170 180 190 200
MHIKLMATMF QNLFPSINVH TVNLNTIKRC LLINYNPDSQ ELDFRHYSVK
210 220 230 240 250
VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGVGLSDS EVEPDGEHNT
260 270 280 290 300
TELPQAVAGR GNMQAQQSAV RLTEIGPRMT LQLIKIQEGV GNGNVLFHSF
310 320 330 340 350
VHKTEEELQA ILAAKEEKLR LKAQRQNQQA ENLQRKQELR EAHKKKSLAG
360 370 380 390 400
IKRARARADG DSDAEDPGAP PEAVGAGQPE DEEDDAEYFR QAVGEEPDED
410 420 430 440 450
LFPTAAKRRR QGGPLGKKQR GKEQRPGNKG RGQGGNWQAL KLQGRSQRGK
460 470
AKPRPRATHQ DSRPASRRRN
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1L1SRW3 | A0A1L1SRW3_MOUSE | Suppressor of SWI4 1 homolog | Ppan | 193 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 411 | Q → P in AAH14688 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK039027 mRNA Translation: BAC30210.1 CH466522 Genomic DNA Translation: EDL25137.1 BC014688 mRNA Translation: AAH14688.1 |
CCDSi | CCDS22887.1 |
RefSeqi | NP_663585.2, NM_145610.2 |
Genome annotation databases
Ensembli | ENSMUST00000004203; ENSMUSP00000004203; ENSMUSG00000004100 |
GeneIDi | 235036 |
KEGGi | mmu:235036 |
UCSCi | uc009ojk.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK039027 mRNA Translation: BAC30210.1 CH466522 Genomic DNA Translation: EDL25137.1 BC014688 mRNA Translation: AAH14688.1 |
CCDSi | CCDS22887.1 |
RefSeqi | NP_663585.2, NM_145610.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 231610, 5 interactors |
IntActi | Q91YU8, 1 interactor |
MINTi | Q91YU8 |
STRINGi | 10090.ENSMUSP00000004203 |
PTM databases
iPTMneti | Q91YU8 |
PhosphoSitePlusi | Q91YU8 |
Proteomic databases
EPDi | Q91YU8 |
jPOSTi | Q91YU8 |
MaxQBi | Q91YU8 |
PaxDbi | Q91YU8 |
PeptideAtlasi | Q91YU8 |
PRIDEi | Q91YU8 |
Genome annotation databases
Ensembli | ENSMUST00000004203; ENSMUSP00000004203; ENSMUSG00000004100 |
GeneIDi | 235036 |
KEGGi | mmu:235036 |
UCSCi | uc009ojk.2, mouse |
Organism-specific databases
CTDi | 56342 |
MGIi | MGI:2178445, Ppan |
Phylogenomic databases
eggNOGi | KOG2963, Eukaryota |
GeneTreei | ENSGT00530000064158 |
HOGENOMi | CLU_026936_0_1_1 |
InParanoidi | Q91YU8 |
OMAi | VTHLMLF |
OrthoDBi | 1199197at2759 |
TreeFami | TF318923 |
Miscellaneous databases
BioGRID-ORCSi | 235036, 9 hits in 18 CRISPR screens |
ChiTaRSi | Ppan, mouse |
PROi | PR:Q91YU8 |
RNActi | Q91YU8, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000004100, Expressed in lung and 69 other tissues |
ExpressionAtlasi | Q91YU8, baseline and differential |
Genevisiblei | Q91YU8, MM |
Family and domain databases
InterProi | View protein in InterPro IPR007109, Brix |
Pfami | View protein in Pfam PF04427, Brix, 1 hit |
SMARTi | View protein in SMART SM00879, Brix, 1 hit |
PROSITEi | View protein in PROSITE PS50833, BRIX, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SSF1_MOUSE | |
Accessioni | Q91YU8Primary (citable) accession number: Q91YU8 Secondary accession number(s): Q8BYM4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 27, 2002 |
Last sequence update: | July 27, 2011 | |
Last modified: | December 2, 2020 | |
This is version 120 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot