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Protein
Submitted name:

ATPase, H+ transporting, lysosomal V1 subunit B1, isoform CRA_a

Gene

Atp6v1b1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • protein-containing complex binding Source: MGI
  • proton transmembrane transporter activity Source: UniProtKB

GO - Biological processi

  • ATP hydrolysis coupled proton transport Source: InterPro
  • ATP metabolic process Source: InterPro
  • calcium ion homeostasis Source: UniProtKB
  • excretion Source: UniProtKB
  • ossification Source: UniProtKB
  • pH reduction Source: UniProtKB
  • proton transmembrane transport Source: UniProtKB
  • regulation of pH Source: UniProtKB
  • sensory perception of sound Source: MGI

Enzyme and pathway databases

ReactomeiR-MMU-1222556 ROS, RNS production in phagocytes
R-MMU-77387 Insulin receptor recycling
R-MMU-917977 Transferrin endocytosis and recycling
R-MMU-983712 Ion channel transport

Protein family/group databases

TCDBi3.A.2.2.6 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

Names & Taxonomyi

Protein namesi
Submitted name:
ATPase, H+ transporting, lysosomal V1 subunit B1, isoform CRA_aImported
Submitted name:
ATPase, H+-transporting, lysosomal V1 subunit B1Imported
Submitted name:
Vacuolar proton translocating ATPase B1 isoformImported
Gene namesi
Name:Atp6v1b1Imported
ORF Names:mCG_142376Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:103285 Atp6v1b1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000006269

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000006431

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 110ATP-synt_ab_NInterPro annotationAdd BLAST67
Domaini167 – 393ATP-synt_abInterPro annotationAdd BLAST227

Phylogenomic databases

eggNOGiKOG1351 Eukaryota
COG1156 LUCA
GeneTreeiENSGT00550000074724
HOVERGENiHBG002176
KOiK02147
OMAiQVKFAQY
OrthoDBiEOG091G04TR
TreeFamiTF300313

Family and domain databases

HAMAPiMF_00310 ATP_synth_B_arch, 1 hit
InterProiView protein in InterPro
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR005723 ATPase_V1-cplx_bsu
IPR027417 P-loop_NTPase
IPR022879 V-ATPase_su_B/beta
PANTHERiPTHR43389 PTHR43389, 1 hit
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039114 V-ATPsynth_beta/V-ATPase_B, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01040 V-ATPase_V1_B, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q91YH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTVDSRSS GFTGNSCDPG TAQEHVQAVT RNYITHPRVT YRTVCSVNGP
60 70 80 90 100
LVVLDQVKFA QYAEIVNFTL PDGTQRSGQV LEVAGTKAIV QVFEGTSGID
110 120 130 140 150
SQKTTCEFTG DILRTPVSED MLGRIFNGSG KPIDKGPAVM AEEFLDINGQ
160 170 180 190 200
PINPHDRIYP EEMIQTGISP IDVMNSIARG QKIPIFSAAG LPHNEIAAQI
210 220 230 240 250
CRQAGLVKKS KAVLDYHEDN FAIVFAAMGV NMETARFFKS DFEQNGTMGN
260 270 280 290 300
VCLFLNLAND PTIERIITPR LALTTAEFLA YQCEKHVLVI LTDMSSYAEA
310 320 330 340 350
LREVSAAREE VPGRRGFPGY MYTDLATIYE RAGRVEGRGG SITQIPILTM
360 370 380 390 400
PNDDITHPIP DLTGFITEGQ IYVDRQLHNR QVYPPINVLP SLSRLMKSAI
410 420 430 440 450
GEGMTRKDHG DVSNQLYACY AIGKDVQAMK AVVGEEALTS EDLLYLEFLQ
460 470 480 490 500
KFEKNFITQG PYENRTVFES LDLGWKLLRI FPKEMLKRIP QSMTDEFYSR
510
QGAQQDPASD TAL
Length:513
Mass (Da):56,791
Last modified:December 1, 2001 - v1
Checksum:i43EE1D236D4F6406
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090647 Genomic DNA No translation available.
BC017127 mRNA Translation: AAH17127.1
AF435091 mRNA Translation: AAN45856.1
AK052604 mRNA Translation: BAC35059.1
AK052707 mRNA Translation: BAC35108.1
AK078810 mRNA Translation: BAC37404.1
AK168980 mRNA Translation: BAE40781.1
CH466523 Genomic DNA Translation: EDK99099.1
RefSeqiNP_598918.1, NM_134157.2
UniGeneiMm.220823

Genome annotation databases

EnsembliENSMUST00000006431; ENSMUSP00000006431; ENSMUSG00000006269
GeneIDi110935
KEGGimmu:110935
UCSCiuc009coc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ91YH6_MOUSE
AccessioniPrimary (citable) accession number: Q91YH6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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