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Entry version 140 (16 Oct 2019)
Sequence version 2 (27 Jul 2011)
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Protein

Coagulation factor XI

Gene

F11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa. EC:3.4.21.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by SERPINA5.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei430Charge relay systemBy similarity1
Active sitei479Charge relay systemBy similarity1
Active sitei574Charge relay systemBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHeparin-binding, Hydrolase, Protease, Serine protease
Biological processBlood coagulation, Hemostasis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-140837 Intrinsic Pathway of Fibrin Clot Formation

Protein family/group databases

MEROPS protease database

More...
MEROPSi
S01.213

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coagulation factor XI (EC:3.4.21.27)
Short name:
FXI
Alternative name(s):
Plasma thromboplastin antecedent
Short name:
PTA
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:F11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:99481 F11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18By similarityAdd BLAST18
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002782719 – 389Coagulation factor XIa heavy chainBy similarityAdd BLAST371
ChainiPRO_0000027828390 – 624Coagulation factor XIa light chainBy similarityAdd BLAST235

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi20 ↔ 103Sequence analysis
Disulfide bondi46 ↔ 76By similarity
Disulfide bondi50 ↔ 56By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi90N-linked (GlcNAc...) asparagineBy similarity1
Disulfide bondi110 ↔ 193By similarity
Glycosylationi126N-linked (GlcNAc...) asparagineBy similarity1
Disulfide bondi136 ↔ 165By similarity
Disulfide bondi140 ↔ 146By similarity
Disulfide bondi200 ↔ 283By similarity
Disulfide bondi226 ↔ 255By similarity
Disulfide bondi230 ↔ 236By similarity
Disulfide bondi291 ↔ 376By similarity
Glycosylationi297N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi317 ↔ 348By similarity
Disulfide bondi321 ↔ 327By similarity
Disulfide bondi339InterchainSequence analysis
Disulfide bondi382 ↔ 499Interchain (between heavy and light chains)PROSITE-ProRule annotation
Disulfide bondi415 ↔ 431By similarity
Glycosylationi449N-linked (GlcNAc...) asparagineBy similarity1
Glycosylationi490N-linked (GlcNAc...) asparagineBy similarity1
Disulfide bondi513 ↔ 580By similarity
Disulfide bondi544 ↔ 559By similarity
Disulfide bondi570 ↔ 598By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Activated by factor XIIa (or XII), which cleaves each polypeptide after Arg-389 into the light chain, which contains the active site, and the heavy chain, which associates with high molecular weight (HMW) kininogen.By similarity
N-glycosylated on both chains. N-glycosylated sites mainly consist of nonfucosylated sialylated biantennary (in high abundance) and/or triantennary (in low abundance) complex structures.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3420

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q91Y47

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q91Y47

PeptideAtlas

More...
PeptideAtlasi
Q91Y47

PRoteomics IDEntifications database

More...
PRIDEi
Q91Y47

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q91Y47

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q91Y47

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q91Y47

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000031645 Expressed in 41 organ(s), highest expression level in liver

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q91Y47 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; disulfide-linked.

Forms a heterodimer with SERPINA5. After activation the heavy and light chains are also linked by a disulfide bond (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000034064

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91Y47

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini20 – 103Apple 1PROSITE-ProRule annotationAdd BLAST84
Domaini110 – 193Apple 2PROSITE-ProRule annotationAdd BLAST84
Domaini200 – 283Apple 3PROSITE-ProRule annotationAdd BLAST84
Domaini291 – 376Apple 4PROSITE-ProRule annotationAdd BLAST86
Domaini390 – 622Peptidase S1PROSITE-ProRule annotationAdd BLAST233

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni547 – 550Heparin-bindingBy similarity4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase S1 family. Plasma kallikrein subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3627 Eukaryota
COG5640 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158569

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112467

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q91Y47

KEGG Orthology (KO)

More...
KOi
K01323

Identification of Orthologs from Complete Genome Data

More...
OMAi
QNCRHSV

Database of Orthologous Groups

More...
OrthoDBi
1314811at2759

TreeFam database of animal gene trees

More...
TreeFami
TF343687

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01100 APPLE_Factor_XI_like, 4 hits
cd00190 Tryp_SPc, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000177 Apple
IPR003609 Pan_app
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00024 PAN_1, 4 hits
PF00089 Trypsin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00005 APPLEDOMAIN
PR00722 CHYMOTRYPSIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00223 APPLE, 4 hits
SM00020 Tryp_SPc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50494 SSF50494, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00495 APPLE, 3 hits
PS50948 PAN, 4 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q91Y47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSLHQVLYF IFFASVSSEC VTKVFKDISF QGGDLSTVFT PSATYCRLVC
60 70 80 90 100
THHPRCLLFT FMAESSSDDP TKWFACILKD SVTEILPMVN MTGAISGYSF
110 120 130 140 150
KQCPQQLSTC SKDVYVNLDM KGMNYNSSVV KNARECQERC TDDAHCQFFT
160 170 180 190 200
YATGYFPSVD HRKMCLLKYT RTGTPTTITK LNGVVSGFSL KSCGLSNLAC
210 220 230 240 250
IRDIFPNTVL ADLNIDSVVA PDAFVCRRIC THHPTCLFFT FFSQAWPKES
260 270 280 290 300
QRHLCLLKTS ESGLPSTRIT KSHALSGFSL QHCRHSVPVF CHPSFYNDTD
310 320 330 340 350
FLGEELDIVD VKGQETCQKT CTNNARCQFF TYYPSHRLCN ERNRRGRCYL
360 370 380 390 400
KLSSNGSPTR ILHGRGGISG YSLRLCKMDN VCTTKINPRV VGGAASVHGE
410 420 430 440 450
WPWQVTLHIS QGHLCGGSII GNQWILTAAH CFSGIETPKK LRVYGGIVNQ
460 470 480 490 500
SEINEGTAFF RVQEMIIHDQ YTTAESGYDI ALLKLESAMN YTDFQRPICL
510 520 530 540 550
PSKGDRNAVH TECWVTGWGY TALRGEVQST LQKAKVPLVS NEECQTRYRR
560 570 580 590 600
HKITNKMICA GYKEGGKDTC KGDSGGPLSC KYNGVWHLVG ITSWGEGCGQ
610 620
KERPGVYTNV AKYVDWILEK TQTV
Length:624
Mass (Da):69,789
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0EEDDEBC56009E97
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti114V → E in AAK40233 (PubMed:9242536).Curated1
Sequence conflicti272S → I in AAK40233 (PubMed:9242536).Curated1
Sequence conflicti368I → L in AAK40233 (PubMed:9242536).Curated1
Sequence conflicti462V → E in AAK40233 (PubMed:9242536).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF356627 mRNA Translation: AAK40233.1
AK005546 mRNA Translation: BAB24114.1
CH466554 Genomic DNA Translation: EDL35542.1
BC019485 mRNA Translation: AAH19485.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS22274.1

NCBI Reference Sequences

More...
RefSeqi
NP_082342.1, NM_028066.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000034064; ENSMUSP00000034064; ENSMUSG00000031645

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
109821

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:109821

UCSC genome browser

More...
UCSCi
uc009los.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF356627 mRNA Translation: AAK40233.1
AK005546 mRNA Translation: BAB24114.1
CH466554 Genomic DNA Translation: EDL35542.1
BC019485 mRNA Translation: AAH19485.1
CCDSiCCDS22274.1
RefSeqiNP_082342.1, NM_028066.2

3D structure databases

SMRiQ91Y47
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034064

Protein family/group databases

MEROPSiS01.213

PTM databases

iPTMnetiQ91Y47
PhosphoSitePlusiQ91Y47
SwissPalmiQ91Y47

Proteomic databases

CPTACinon-CPTAC-3420
MaxQBiQ91Y47
PaxDbiQ91Y47
PeptideAtlasiQ91Y47
PRIDEiQ91Y47

Genome annotation databases

EnsembliENSMUST00000034064; ENSMUSP00000034064; ENSMUSG00000031645
GeneIDi109821
KEGGimmu:109821
UCSCiuc009los.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2160
MGIiMGI:99481 F11

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00940000158569
HOGENOMiHOG000112467
InParanoidiQ91Y47
KOiK01323
OMAiQNCRHSV
OrthoDBi1314811at2759
TreeFamiTF343687

Enzyme and pathway databases

ReactomeiR-MMU-140837 Intrinsic Pathway of Fibrin Clot Formation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
F11 mouse

Protein Ontology

More...
PROi
PR:Q91Y47

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000031645 Expressed in 41 organ(s), highest expression level in liver
GenevisibleiQ91Y47 MM

Family and domain databases

CDDicd01100 APPLE_Factor_XI_like, 4 hits
cd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR000177 Apple
IPR003609 Pan_app
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00024 PAN_1, 4 hits
PF00089 Trypsin, 1 hit
PRINTSiPR00005 APPLEDOMAIN
PR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00223 APPLE, 4 hits
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS00495 APPLE, 3 hits
PS50948 PAN, 4 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA11_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91Y47
Secondary accession number(s): Q9DAT3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: July 27, 2011
Last modified: October 16, 2019
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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