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Protein
Submitted name:

Protocadherin beta 20

Gene

Pcdhb20

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell adhesion Source: GO_Central
  • homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin beta 20Imported
Gene namesi
Name:Pcdhb20Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136758 Pcdhb20

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei687 – 710HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501509953929 – 799Sequence analysisAdd BLAST771

Expressioni

Gene expression databases

BgeeiENSMUSG00000046191 Expressed in 19 organ(s), highest expression level in embryo

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137038

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 240CAInterPro annotationAdd BLAST86
Domaini264 – 345CAInterPro annotationAdd BLAST82
Domaini368 – 449CAInterPro annotationAdd BLAST82
Domaini473 – 559CAInterPro annotationAdd BLAST87
Domaini589 – 670CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOVERGENiHBG054878
KOiK16494
OMAiGNYGKIS
OrthoDBiEOG091G024L
TreeFamiTF332299

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits

Sequencei

Sequence statusi: Complete.

Q91XZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRRRALILQ KRQVLVFFVF LGLSQASAES LRYSVAEETE IGSFVANLAK
60 70 80 90 100
DLGLGVAELS SREARVVSDD NKKHLLLNLL TGDMLLNERL DREELCGSTQ
110 120 130 140 150
PCVLPFQVVL ENPLQFYRAE LHVRDINDHS PTFLDKEITI KISESTTIGA
160 170 180 190 200
TFLIENAQDL DIGSNSLQDY SISPSSYFYV KIHDSGDGKI YPELVLDKAL
210 220 230 240 250
DHEEESELRL TLTALDGGSP PRSGTTLIVI KVLDINDNAP EFAQSFYEVQ
260 270 280 290 300
VPEDMPIGSS ITAISAKDLD MGIYGKISYS FLHASEDIRK TFEINPTSGE
310 320 330 340 350
VNLRSLMDFE VIQSYSVNIQ ATDGGGLSAK CTLSVKVLDI NDNAPEVIMS
360 370 380 390 400
SVTKAIPENA SETLVALFSV RDQDSGDNGR ILCSIQDDLP FILKPSFKNF
410 420 430 440 450
FTLLSEKALD RERRAEYNIT ITASDMGTPR LTTQHTIRVQ VSDINDNAPA
460 470 480 490 500
FTQTSYTMFI YENNSPALHI GTISATDKDS GSNAHITYSL LPAQDPELAL
510 520 530 540 550
ASLISINADN GQLFALRALD YEVLQAFEFQ VGATDRGSPA LSSQTLVRVV
560 570 580 590 600
VLDDNDNAPF VLYPMQNASA PCTELLPRVA EPGYLVTKVV AVDRDSGQNA
610 620 630 640 650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHRL VLLVKDNGDP
660 670 680 690 700
PRSASVTLHV LVVDGFSQPY LPLPEVARDP AQEEDVLTLY LVIALASVSS
710 720 730 740 750
LFLLSVLLFV GVRLCRRARA ASLGGCSVPE GHFPGHLVDV TGTGTLSQNY
760 770 780 790
QYEVCFTGGT GTNEFKFLRP VMPSLQLHDP DSNMLEKENF RNSLGFNIQ
Length:799
Mass (Da):87,800
Last modified:December 1, 2001 - v1
Checksum:i99C7A595F1673147
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA No translation available.
BC031895 mRNA Translation: AAH31895.1
AY013782 mRNA Translation: AAK26071.1
AK045399 mRNA Translation: BAC32346.1
AK046137 mRNA Translation: BAC32611.1
RefSeqiNP_444375.2, NM_053145.2
UniGeneiMm.172449

Genome annotation databases

EnsembliENSMUST00000052179; ENSMUSP00000137038; ENSMUSG00000046191
GeneIDi93891
KEGGimmu:93891
UCSCiuc008eqf.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA No translation available.
BC031895 mRNA Translation: AAH31895.1
AY013782 mRNA Translation: AAK26071.1
AK045399 mRNA Translation: BAC32346.1
AK046137 mRNA Translation: BAC32611.1
RefSeqiNP_444375.2, NM_053145.2
UniGeneiMm.172449

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137038

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000052179; ENSMUSP00000137038; ENSMUSG00000046191
GeneIDi93891
KEGGimmu:93891
UCSCiuc008eqf.2 mouse

Organism-specific databases

CTDi93891
MGIiMGI:2136758 Pcdhb20

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOVERGENiHBG054878
KOiK16494
OMAiGNYGKIS
OrthoDBiEOG091G024L
TreeFamiTF332299

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046191 Expressed in 19 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ91XZ9_MOUSE
AccessioniPrimary (citable) accession number: Q91XZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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