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Protein
Submitted name:

Protocadherin beta 3

Gene

Pcdhb3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell adhesion Source: GO_Central
  • homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin beta 3Imported
Gene namesi
Name:Pcdhb3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136737 Pcdhb3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei688 – 711HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000045498 Expressed in 146 organ(s), highest expression level in hindbrain

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059180

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 131CAInterPro annotationAdd BLAST88
Domaini155 – 240CAInterPro annotationAdd BLAST86
Domaini264 – 345CAInterPro annotationAdd BLAST82
Domaini368 – 449CAInterPro annotationAdd BLAST82
Domaini473 – 559CAInterPro annotationAdd BLAST87
Domaini589 – 670CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOGENOMiHOG000220892
HOVERGENiHBG054878
KOiK16494
OMAiNKQHFQL
OrthoDBiEOG091G024L
TreeFamiTF332299

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR030733 PCDHB15
PANTHERiPTHR24028:SF97 PTHR24028:SF97, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 6 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits

Sequencei

Sequence statusi: Complete.

Q91XZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAREESFLK QRQVLLLFVF LGGSLAGSMS RRYSVAEEKE KGFVIANLAT
60 70 80 90 100
DLGLSIEELA ERRAQAISKG NIQYFQLSHQ TGDLLLVEKL DREDLCGSTE
110 120 130 140 150
PCVLHFQILL HDPLQFITNE LEVIDVNDHA PEFFENAMQL KVLENSVPGT
160 170 180 190 200
VIPLGNAVDL DVGRNGLQNY TVSPTSHFHV HTRRRRDGRK YPELVLDRAL
210 220 230 240 250
DREEQSEISL TLTALDGGSP PRSGTTQVHI LVLDTNDNAP EFTQSLYEVQ
260 270 280 290 300
ILEKSPIGSV ITTVSASDLD TGNFGAISYV FFHASEEILE TFRLNSSTGN
310 320 330 340 350
IQLLKGLDYE AINTYEVDIE AKDGGGLSGK CTVIVQILDV NDNPPELTLS
360 370 380 390 400
SVNSLIPENS AETVVAVFSV SDLDSGDNGR VTCSIQNDLP FILKPSVENF
410 420 430 440 450
YTIASEWALD REIRAEYNIT ITVSDLGTPR LTTQHTITVQ VSDLNDNAPA
460 470 480 490 500
FTQTSYTMSV RENNSPALHI GTISATDSDS GSNAHITYSL LPPHDPQLAL
510 520 530 540 550
DSLISINADN GQLFALRALD YEALQAFEFH VGATDGGSPA LSSQALVRVV
560 570 580 590 600
VLDDNDNAPF VLYPLQNASA PCTELLPRAA ETGYLVTKVV AVDRDSGQNA
610 620 630 640 650
WLSFQLLKST EPGLFSVWAH NGEVRTARLL SERDMLKQKL LLLVKDNGDP
660 670 680 690 700
PRSASVTLNV LLVDGFSQPY LPLPEVARDS VQNDVDLLTL YLVIALASVS
710 720 730 740 750
SLFLLSVLLF VGVRLCRRAR AASMGGCSVP EGHFPGHLVD VSGMGTLSQS
760 770 780
YQYEVCLTGD AGTGEFKLLN PVIPNLFLEE SERS
Length:784
Mass (Da):85,569
Last modified:December 1, 2001 - v1
Checksum:i4712EAEB00CC2D49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020974 Genomic DNA No translation available.
BC079557 mRNA Translation: AAH79557.1
AY013785 mRNA Translation: AAK26074.1
AK030570 mRNA Translation: BAC27027.1
RefSeqiNP_444358.2, NM_053128.2
UniGeneiMm.82308

Genome annotation databases

EnsembliENSMUST00000051754; ENSMUSP00000059180; ENSMUSG00000045498
GeneIDi93874
KEGGimmu:93874
UCSCiuc008epo.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020974 Genomic DNA No translation available.
BC079557 mRNA Translation: AAH79557.1
AY013785 mRNA Translation: AAK26074.1
AK030570 mRNA Translation: BAC27027.1
RefSeqiNP_444358.2, NM_053128.2
UniGeneiMm.82308

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059180

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000051754; ENSMUSP00000059180; ENSMUSG00000045498
GeneIDi93874
KEGGimmu:93874
UCSCiuc008epo.1 mouse

Organism-specific databases

CTDi56132
MGIiMGI:2136737 Pcdhb3

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOGENOMiHOG000220892
HOVERGENiHBG054878
KOiK16494
OMAiNKQHFQL
OrthoDBiEOG091G024L
TreeFamiTF332299

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045498 Expressed in 146 organ(s), highest expression level in hindbrain

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR030733 PCDHB15
PANTHERiPTHR24028:SF97 PTHR24028:SF97, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 6 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ91XZ7_MOUSE
AccessioniPrimary (citable) accession number: Q91XZ7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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