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Entry version 139 (05 Jun 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Inactive peptidyl-prolyl cis-trans isomerase FKBP6

Gene

Fkbp6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.3 Publications

Caution

Although it contains a PPIase FKBP-type domain, does not show peptidyl-prolyl cis-trans isomerase activity.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inactive peptidyl-prolyl cis-trans isomerase FKBP6
Short name:
Inactive PPIase FKBP6
Alternative name(s):
36 kDa FK506-binding protein
Short name:
36 kDa FKBP
Short name:
FKBP-36
FK506-binding protein 6
Short name:
FKBP-6
Immunophilin FKBP36
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fkbp6
Synonyms:Fkbp36
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2137612 Fkbp6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Males mice are sterile and aspermic due to abnormal pachytene spermatocytes, characterized by the appearance of unusual inclusion bodies and dense compacted nuclei. Spermatocytes fail to proceed beyond the pachytene stage due to abnormal pairing and misalignments between homologous chromosomes, non-homologous partner switches and autosynapsis of X chromosome cores in meiotic spermatocytes. No other abnormalities are detected in any tissues of males. Females mice are fertile (PubMed:12764197). Spermatocytes show derepressed LINE-1 retrotransposon and reduced DNA methylation due to deficient nuclear accumulation of Miwi2 (PubMed:22902560).2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi254K → A: Abolishes interaction with HSP90. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000753301 – 327Inactive peptidyl-prolyl cis-trans isomerase FKBP6Add BLAST327

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q91XW8

PRoteomics IDEntifications database

More...
PRIDEi
Q91XW8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q91XW8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q91XW8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis-specific.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Present in spermatocytes. Expression is lost as cells exit prophase I. Not detected in spermatids (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000040013 Expressed in 27 organ(s), highest expression level in testis

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q91XW8 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with HSP72/HSPA2 and CLTC.

Interacts with GAPDH; leading to inhibit GAPDH catalytic activity (By similarity).

Interacts (via TPR repeats) with HSP90.

By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
220490, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000043193

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91XW8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 143PPIase FKBP-typePROSITE-ProRule annotationAdd BLAST90
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati171 – 204TPR 1Add BLAST34
Repeati219 – 252TPR 2Add BLAST34
Repeati253 – 286TPR 3Add BLAST34

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FKBP6 family.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0543 Eukaryota
COG0545 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158514

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000251594

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q91XW8

KEGG Orthology (KO)

More...
KOi
K09572

Identification of Orthologs from Complete Genome Data

More...
OMAi
GCPPRIK

Database of Orthologous Groups

More...
OrthoDBi
1465346at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q91XW8

TreeFam database of animal gene trees

More...
TreeFami
TF354214

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042282 FKBP6/shu
IPR001179 PPIase_FKBP_dom
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR46674 PTHR46674, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00254 FKBP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q91XW8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGGSTRDPGA LEGAGILGQS PYERLSQRML DISGDRGVLK DIIREGTGDT
60 70 80 90 100
VTPDASVLVK YSGYLEHMDK PFDSNCFRKT PRLMKLGEDI TLWGMELGLL
110 120 130 140 150
SMRKGELARF LFKPAYAYGT LGCPPLIPPN ATVLFEIELI DFLDSAESDK
160 170 180 190 200
FCALSAEQQE QFPLQKVLKV AATEREFGNY LFRQNRFCDA KVRYKRALLL
210 220 230 240 250
LHRRLATCEE QHLVEPAVLL VLLNLSFVYL KLDRPAMALR YGEQALLIDK
260 270 280 290 300
RNAKALFRCG QACLLLTEYE RARDFLVRAQ KEQPCNHDIN NELKKLSSHY
310 320
RDYVDREREM CHRMFAPCGS RSSVGGN
Length:327
Mass (Da):37,125
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9A2AE310DDC064CD
GO
Isoform 2 (identifier: Q91XW8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-18: MGGSTRDPGALEGAGILG → MSVFSRLRNGIPPSRDDC
     157-196: Missing.

Show »
Length:287
Mass (Da):32,599
Checksum:iD2F13117FF2DAF0A
GO
Isoform 3 (identifier: Q91XW8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-18: MGGSTRDPGALEGAGILG → MSVFSRLRNGIPPSRDDC

Show »
Length:327
Mass (Da):37,516
Checksum:i30B43484430A0187
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti19Q → H in BAC41058 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0051851 – 18MGGST…AGILG → MSVFSRLRNGIPPSRDDC in isoform 2 and isoform 3. 3 PublicationsAdd BLAST18
Alternative sequenceiVSP_005186157 – 196Missing in isoform 2. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY029192 mRNA Translation: AAK39645.1
AF367709 mRNA Translation: AAK53411.1
AF367710 mRNA Translation: AAK53412.1
AF367711 mRNA Translation: AAK53413.1
AK090036 mRNA Translation: BAC41058.1
AC074359 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19373.1
CH466529 Genomic DNA Translation: EDL19374.1
BC139092 mRNA Translation: AAI39093.1
BC139097 mRNA Translation: AAI39098.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19738.1 [Q91XW8-3]
CCDS80425.1 [Q91XW8-1]
CCDS80426.1 [Q91XW8-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001264820.1, NM_001277891.1 [Q91XW8-3]
NP_001264821.1, NM_001277892.1 [Q91XW8-1]
NP_001264822.1, NM_001277893.1 [Q91XW8-2]
NP_291049.1, NM_033571.3 [Q91XW8-3]
XP_011239215.1, XM_011240913.1 [Q91XW8-3]
XP_011239217.1, XM_011240915.1 [Q91XW8-2]
XP_017176679.1, XM_017321190.1 [Q91XW8-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000044972; ENSMUSP00000043193; ENSMUSG00000040013 [Q91XW8-3]
ENSMUST00000201534; ENSMUSP00000144471; ENSMUSG00000040013 [Q91XW8-3]
ENSMUST00000201784; ENSMUSP00000144381; ENSMUSG00000040013 [Q91XW8-1]
ENSMUST00000201791; ENSMUSP00000144460; ENSMUSG00000040013 [Q91XW8-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
94244

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:94244

UCSC genome browser

More...
UCSCi
uc008zyb.2 mouse [Q91XW8-3]
uc008zyc.2 mouse [Q91XW8-2]
uc008zyd.1 mouse [Q91XW8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029192 mRNA Translation: AAK39645.1
AF367709 mRNA Translation: AAK53411.1
AF367710 mRNA Translation: AAK53412.1
AF367711 mRNA Translation: AAK53413.1
AK090036 mRNA Translation: BAC41058.1
AC074359 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19373.1
CH466529 Genomic DNA Translation: EDL19374.1
BC139092 mRNA Translation: AAI39093.1
BC139097 mRNA Translation: AAI39098.1
CCDSiCCDS19738.1 [Q91XW8-3]
CCDS80425.1 [Q91XW8-1]
CCDS80426.1 [Q91XW8-2]
RefSeqiNP_001264820.1, NM_001277891.1 [Q91XW8-3]
NP_001264821.1, NM_001277892.1 [Q91XW8-1]
NP_001264822.1, NM_001277893.1 [Q91XW8-2]
NP_291049.1, NM_033571.3 [Q91XW8-3]
XP_011239215.1, XM_011240913.1 [Q91XW8-3]
XP_011239217.1, XM_011240915.1 [Q91XW8-2]
XP_017176679.1, XM_017321190.1 [Q91XW8-3]

3D structure databases

SMRiQ91XW8
ModBaseiSearch...

Protein-protein interaction databases

BioGridi220490, 1 interactor
STRINGi10090.ENSMUSP00000043193

PTM databases

iPTMnetiQ91XW8
PhosphoSitePlusiQ91XW8

Proteomic databases

PaxDbiQ91XW8
PRIDEiQ91XW8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044972; ENSMUSP00000043193; ENSMUSG00000040013 [Q91XW8-3]
ENSMUST00000201534; ENSMUSP00000144471; ENSMUSG00000040013 [Q91XW8-3]
ENSMUST00000201784; ENSMUSP00000144381; ENSMUSG00000040013 [Q91XW8-1]
ENSMUST00000201791; ENSMUSP00000144460; ENSMUSG00000040013 [Q91XW8-2]
GeneIDi94244
KEGGimmu:94244
UCSCiuc008zyb.2 mouse [Q91XW8-3]
uc008zyc.2 mouse [Q91XW8-2]
uc008zyd.1 mouse [Q91XW8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8468
MGIiMGI:2137612 Fkbp6

Phylogenomic databases

eggNOGiKOG0543 Eukaryota
COG0545 LUCA
GeneTreeiENSGT00940000158514
HOGENOMiHOG000251594
InParanoidiQ91XW8
KOiK09572
OMAiGCPPRIK
OrthoDBi1465346at2759
PhylomeDBiQ91XW8
TreeFamiTF354214

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Fkbp10 mouse

Protein Ontology

More...
PROi
PR:Q91XW8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000040013 Expressed in 27 organ(s), highest expression level in testis
GenevisibleiQ91XW8 MM

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR042282 FKBP6/shu
IPR001179 PPIase_FKBP_dom
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR46674 PTHR46674, 1 hit
PfamiView protein in Pfam
PF00254 FKBP_C, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFKBP6_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91XW8
Secondary accession number(s): Q8C1Y1, Q91VB7, Q91Y30
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: December 1, 2001
Last modified: June 5, 2019
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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