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Protein

Brain acid soluble protein 1

Gene

Basp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • protein domain specific binding Source: MGI
  • transcription corepressor activity Source: UniProtKB
  • transcription regulatory region DNA binding Source: UniProtKB

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Brain acid soluble protein 1
Alternative name(s):
22 kDa neuronal tissue-enriched acidic protein
Neuronal axonal membrane protein NAP-22
Gene namesi
Name:Basp1
Synonyms:Nap22
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1917600 Basp1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cell projection, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001428962 – 226Brain acid soluble protein 1Add BLAST225

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Cross-linki25Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei31PhosphothreonineCombined sources1
Modified residuei36PhosphothreonineCombined sources1
Modified residuei40PhosphoserineCombined sources1
Cross-linki86Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei92PhosphoserineCombined sources1
Modified residuei128PhosphoserineCombined sources1
Modified residuei131PhosphoserineBy similarity1
Cross-linki159Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei160PhosphoserineBy similarity1
Modified residuei167PhosphoserineBy similarity1
Modified residuei169PhosphoserineCombined sources1
Modified residuei173PhosphoserineCombined sources1
Modified residuei192PhosphoserineCombined sources1
Modified residuei218PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Lipoprotein, Myristate, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ91XV3
MaxQBiQ91XV3
PaxDbiQ91XV3
PeptideAtlasiQ91XV3
PRIDEiQ91XV3

PTM databases

iPTMnetiQ91XV3
PhosphoSitePlusiQ91XV3
SwissPalmiQ91XV3

Expressioni

Gene expression databases

BgeeiENSMUSG00000045763 Expressed in 294 organ(s), highest expression level in forebrain
GenevisibleiQ91XV3 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi213993, 5 interactors
IntActiQ91XV3, 7 interactors
MINTiQ91XV3
STRINGi10090.ENSMUSP00000053943

Structurei

3D structure databases

ProteinModelPortaliQ91XV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BASP1 family.Curated

Phylogenomic databases

eggNOGiENOG410J14G Eukaryota
ENOG4112CMG LUCA
GeneTreeiENSGT00730000111450
HOGENOMiHOG000095176
InParanoidiQ91XV3
KOiK17272
OMAiTNSDQTI

Family and domain databases

InterProiView protein in InterPro
IPR008408 BASP1
PANTHERiPTHR23212 PTHR23212, 1 hit
PfamiView protein in Pfam
PF05466 BASP1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q91XV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGKLSKKKK GYNVNDEKAK DKDKKAEGAG TEEEGTPKES EPQAAADATE
60 70 80 90 100
VKESTEEKPK DAADGEAKAE EKEADKAAAA KEEAPKAEPE KSEGAAEEQP
110 120 130 140 150
EPAPAPEQEA AAPGPAAGGE APKAGEASAE STGAADGAAP EEGEAKKTEA
160 170 180 190 200
PAAAGPEAKS DAAPAASDSK PSSAEPAPSS KETPAASEAP SSAAKAPAPA
210 220
APAAAEPQAE APAAAASSEQ SVAVKE
Length:226
Mass (Da):22,087
Last modified:January 23, 2007 - v3
Checksum:iB41CCAAB447C705D
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BRZ4A0A2I3BRZ4_MOUSE
Brain acid soluble protein 1
Basp1
17Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046714 Genomic DNA Translation: BAB62404.1
CCDSiCCDS27398.1
RefSeqiNP_081671.1, NM_027395.2
UniGeneiMm.29586

Genome annotation databases

EnsembliENSMUST00000058845; ENSMUSP00000053943; ENSMUSG00000045763
GeneIDi70350
KEGGimmu:70350
UCSCiuc007vix.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046714 Genomic DNA Translation: BAB62404.1
CCDSiCCDS27398.1
RefSeqiNP_081671.1, NM_027395.2
UniGeneiMm.29586

3D structure databases

ProteinModelPortaliQ91XV3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi213993, 5 interactors
IntActiQ91XV3, 7 interactors
MINTiQ91XV3
STRINGi10090.ENSMUSP00000053943

PTM databases

iPTMnetiQ91XV3
PhosphoSitePlusiQ91XV3
SwissPalmiQ91XV3

Proteomic databases

EPDiQ91XV3
MaxQBiQ91XV3
PaxDbiQ91XV3
PeptideAtlasiQ91XV3
PRIDEiQ91XV3

Protocols and materials databases

DNASUi70350
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000058845; ENSMUSP00000053943; ENSMUSG00000045763
GeneIDi70350
KEGGimmu:70350
UCSCiuc007vix.2 mouse

Organism-specific databases

CTDi10409
MGIiMGI:1917600 Basp1

Phylogenomic databases

eggNOGiENOG410J14G Eukaryota
ENOG4112CMG LUCA
GeneTreeiENSGT00730000111450
HOGENOMiHOG000095176
InParanoidiQ91XV3
KOiK17272
OMAiTNSDQTI

Miscellaneous databases

ChiTaRSiBasp1 mouse
PROiPR:Q91XV3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045763 Expressed in 294 organ(s), highest expression level in forebrain
GenevisibleiQ91XV3 MM

Family and domain databases

InterProiView protein in InterPro
IPR008408 BASP1
PANTHERiPTHR23212 PTHR23212, 1 hit
PfamiView protein in Pfam
PF05466 BASP1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBASP1_MOUSE
AccessioniPrimary (citable) accession number: Q91XV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 109 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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