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Entry version 133 (12 Aug 2020)
Sequence version 2 (27 Jul 2011)
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Protein

Dynein heavy chain 8, axonemal

Gene

Dnah8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi2087 – 2094ATPSequence analysis8
Nucleotide bindingi2369 – 2376ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dynein heavy chain 8, axonemal
Alternative name(s):
Axonemal beta dynein heavy chain 8
Ciliary dynein heavy chain 8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dnah8
Synonyms:Dnahc8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:107714, Dnah8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Flagellum, Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002740451 – 4731Dynein heavy chain 8, axonemalAdd BLAST4731

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei917PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q91XQ0

PRoteomics IDEntifications database

More...
PRIDEi
Q91XQ0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q91XQ0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q91XQ0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 and/or isoform 2 are expressed in spermatocytes and mature sperm (at protein level). Testis-specific. Accumulates exclusively in mid to late spermatocytes.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000033826, Expressed in spermatocyte and 96 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q91XQ0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q91XQ0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Consists of at least two heavy chains and a number of intermediate and light chains.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
199249, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000127878

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q91XQ0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91XQ0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2049 – 2271AAA 1By similarityAdd BLAST223
Regioni2331 – 2550AAA 2By similarityAdd BLAST220
Regioni2657 – 2910AAA 3By similarityAdd BLAST254
Regioni3021 – 3275AAA 4By similarityAdd BLAST255
Regioni3290 – 3587StalkBy similarityAdd BLAST298
Regioni3673 – 3903AAA 5By similarityAdd BLAST231
Regioni4118 – 4332AAA 6By similarityAdd BLAST215

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili145 – 169Sequence analysisAdd BLAST25
Coiled coili1543 – 1567Sequence analysisAdd BLAST25
Coiled coili3313 – 3405Sequence analysisAdd BLAST93
Coiled coili3531 – 3583Sequence analysisAdd BLAST53
Coiled coili3836 – 3871Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi10 – 54Pro-richAdd BLAST45

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head, which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes ATP, the others may serve a regulatory function.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3595, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158992

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000038_9_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q91XQ0

KEGG Orthology (KO)

More...
KOi
K10408

Identification of Orthologs from Complete Genome Data

More...
OMAi
CAKIFKG

Database of Orthologous Groups

More...
OrthoDBi
6295at2759

TreeFam database of animal gene trees

More...
TreeFami
TF316836

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR041589, DNAH3_AAA_lid_1
IPR042228, Dynein_2_C
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041466, Dynein_AAA5_ext
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013594, Dynein_heavy_dom-1
IPR013602, Dynein_heavy_dom-2
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676, PTHR10676, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 1 hit
PF17857, AAA_lid_1, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08385, DHC_N1, 1 hit
PF08393, DHC_N2, 1 hit
PF17852, Dynein_AAA_lid, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q91XQ0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESEEGNAEP PPPSEEAPPP VVEEAPPPLP PEDTAPPPPE EQAPPPEGDA
60 70 80 90 100
APPPTGDAFQ LTVEGEAPHP EDPKLLSEQG PATSVTDYRS LIPSDEEVTL
110 120 130 140 150
PEDEESGQAR VRARHTPRPA QSVLSDGISQ SSRRPSKFRR SMTGIPNLQE
160 170 180 190 200
TLKEKQARFR EARENRKMKI GPSHKYIFEV LGEKLGLDLV TVEELILDCP
210 220 230 240 250
SLDPFTSFFE KGGCKTLKFL YQEGEVPGFE CGRTITGVPK GGKMMRIYVD
260 270 280 290 300
NAAPDKLKGL CLFFVRCRND VAINSKTIHE DVLFSFLDAS KGLLEGIKHM
310 320 330 340 350
LKSIFLPAIL ATSNWGALNQ SKQGESEKHI FIETIHRYLA SLDDATISIE
360 370 380 390 400
GTVMLKKVDN IDFSKLHTFE EVTAAASSSE MVHQLEEVLM VWYKQIEQVL
410 420 430 440 450
IESEQMRKEA DDSGPLTELE HWKRMSAKFN FIIEQIKGSN CKAVINVLNV
460 470 480 490 500
AHSKLLKNWR DLDARITDSA NESKDNVRYL YTLEKVCQPL YNYDLVSMAH
510 520 530 540 550
GIQNLINAIR MIHSVSRYYN TSERMTSLFI KVTNQMVTAC KAYITDGGTN
560 570 580 590 600
HVWDQETPAV LKKIQDCIFL FKEYQASFHK TRKQILESSG EKSFEVSEMY
610 620 630 640 650
IFGKFEAFCK RLEKITEMIT IVQTYSALSN STIEGIDILG IKFKNIYQGI
660 670 680 690 700
KKNQYDILDP RRTEFDTDFT EFMGKINILE IQIQAFMNST FGKILSSQQA
710 720 730 740 750
LQLLQRFQKL NIPCLHLEIN HTIERILQCY VAELEFTKKL YLSQKDDPPL
760 770 780 790 800
ARNMPPIAGK ILWVRQLFRR INEPINYFFK NSDILSSTEG KAVIRQYNRI
810 820 830 840 850
AYVLVEFEVA YHTAWFKEVS QLQYALQATL FVRHPETGKL LVNFDPKILE
860 870 880 890 900
VVRETKCMIK MKLDVPEQAK NLLKLESKLK ADKLYLQGLL QYYDDLCQEV
910 920 930 940 950
PSVFVNLMTP KMKKVESVLR QGLTVLTWSS LMLESFFKEV ESVLDMFNQL
960 970 980 990 1000
LKKVNDLCEM HIDTVLKEIA KTLLISLSDS GTTKVEDMLT LNETYTKECA
1010 1020 1030 1040 1050
DILNHKSRHV EEAVKELILI FEQIYEVKYT GKAAKSVKEQ RKRVVFGSEA
1060 1070 1080 1090 1100
EETEGLDFES TTMEVDTNDK EDEFKKECKE VYAFFSHQLL DSLQKATRLS
1110 1120 1130 1140 1150
LDTMKRRIFV GSQGRRRSED IVSFIKTEVH LAIPNVVMVP SLDDIQQAIN
1160 1170 1180 1190 1200
RMIQLTLEVS RGVAHWGQQQ VRQIKSFQNN SRGSDQPPAS GKPLKKEERS
1210 1220 1230 1240 1250
FEETIPARKL KNFYPGVAEH KDISKLVLLL SSSVNSLRKA ATEALQDFQK
1260 1270 1280 1290 1300
YKTLWIEDRH VKVKEFLANN PSLTEIRSEI LHYATLEQEI KELKPIIVVG
1310 1320 1330 1340 1350
SLELHTEPMK LALSIEAKAW KMLLCRYLNE EYKKKMSDMI TFINEYLKKL
1360 1370 1380 1390 1400
SRPIRDLDDV RFAMEALSCI RDNEIQMDMT LGPIEEAYGI LNRFEVKVTK
1410 1420 1430 1440 1450
EESEGVDTLR YSFNKLQSKA VSVQGELVKV QPKFKSNLLE SVKVFCEDVI
1460 1470 1480 1490 1500
NFTEAYETEG PMVPNIPPQE ASNRLQIFQA NFDDLWRKFV TYSSGEQLFG
1510 1520 1530 1540 1550
LPVTDYEVLH KTRKELNLLQ KLYGLYDTVM GSISGYYEIL WGDVDIEKIN
1560 1570 1580 1590 1600
AELQEFQNRC RKLPRALKDW QAFLDLKKRI DDFSESCPLL EMMTNKAMKQ
1610 1620 1630 1640 1650
RHWDRISELT GTPFDVESDT FCLRNIMEAP LLKNKDDIED ICISAIKEKD
1660 1670 1680 1690 1700
IEAKLTQVIE NWTYQNLSFA AFKGKGELLL KGTESGEIIT LMEDSLMVLG
1710 1720 1730 1740 1750
SLLSNRYNTP FKKNIQNWVF KLSTSSDIIE EWLIVQNLWV YLEAVFVGGD
1760 1770 1780 1790 1800
IAKQLPQEAK RFQNIDKSWI KIMQRAHENP NVISCCVGDE TMGQLLPHLH
1810 1820 1830 1840 1850
EQLEVCQKSL TGYLEKKRLL FPRFFFVSDP VLLEILGQAS DSHTIQPHLP
1860 1870 1880 1890 1900
AVSDNINEVT FHAKDYDRMT AVISREGEKI MLDTPVMAKG PVEIWLLDLL
1910 1920 1930 1940 1950
KVQMSSLHNI IRSAFYQISD SGFLLLPFLN HFPAQVGLLG IQMLWTHDSE
1960 1970 1980 1990 2000
EALNNAKDDR KIMQITNQKF LDILNTLISQ TTHDLTKFDR VKFETLITIH
2010 2020 2030 2040 2050
VHQRDIFDDL VKMHIKSVTD FEWLKQSRFY FKEDLDQTVV SITDVDFIYQ
2060 2070 2080 2090 2100
NEFLGCTDRL VITPLTDRCY ITLAQALGMN MGGAPAGPAG TGKTETTKDM
2110 2120 2130 2140 2150
GRCLGKYVVV FNCSDQMDFR GLGRIFKGLA QSGSWGCFDE FNRIELPVLS
2160 2170 2180 2190 2200
VAAQQIYIVL TARKERKKQF IFSDGDCVDL NPEFGIFLTM NPGYAGRQEL
2210 2220 2230 2240 2250
PENLKIQFRT VAMMVPDRQI IMRVKLASCG FLENVILAQK FYVLYKLCEE
2260 2270 2280 2290 2300
QLTKQVHYDF GLRNILSVLR TLGSQKRARP EDSELSTVMR GLRDMNLSKL
2310 2320 2330 2340 2350
VDEDEPLFLS LINDLFPGLQ LDSSTYAELQ SAVDNQVNLE GLINHPPWNL
2360 2370 2380 2390 2400
KLVQLYETSL VRHGLMTLGP SGSGKTTVIT ILMKSLTECG RPHREMRMNP
2410 2420 2430 2440 2450
KAITAPQMFG RLDTATNDWT DGIFSTLWRK TLKAKKGENI FLILDGPVDA
2460 2470 2480 2490 2500
IWIENLNSVL DDNKTLTLAN GDRIPMAPTC KLLFEVHNIE NASPATVSRM
2510 2520 2530 2540 2550
GMVYISSSAL SWRPILQAWL KKRSQQEASV FLSLYDKVFE DAYTYMKLSL
2560 2570 2580 2590 2600
NPKMQLLECN YIMQSLNLLE GLIPSKEEGG VSSGDHLHKL FVFGLMWSLG
2610 2620 2630 2640 2650
ALLELDSREK LEVFLRGHGS KLNLPEIPKG SQQTMYEFYV TDYGDWEHWN
2660 2670 2680 2690 2700
KRIQPYFYPT DSIPEYSSIL VPNVDNIRTN FLIDTIAKQH KAVLLTGEQG
2710 2720 2730 2740 2750
TAKTVMVKAY LKKYDPEVQL SKSLNFSSAT EPMMFQRTIE SYVDKRMGST
2760 2770 2780 2790 2800
YGPPGGRKMT VFIDDINMPV INEWGDQITN EIVRQMMEME GMYSLDKPGD
2810 2820 2830 2840 2850
FTTIVDVQLI AAMIHPGGGR NDIPQRLKRQ FTVFNCTLPS NTSIDKIFGI
2860 2870 2880 2890 2900
IGCGYFDPCR KFRPEICDMV GNLVSVSRVL WQWTKVKMLP TPSKFHYIFN
2910 2920 2930 2940 2950
LRDLSRIWQG MLTVKAEECS SIPILLSLFK HECNRVIADR FITPDDEQWF
2960 2970 2980 2990 3000
NSQLIRAVEE NISPEVAANI LPEPYFVDFL RDMPEPTGDE PEDTMFEVPK
3010 3020 3030 3040 3050
IYELVPSFEF LSEKLQFYQR QFNEIIRGTS LDLVFFKDAM THLVKISRII
3060 3070 3080 3090 3100
RTSCGNALLV GVGGSGKQSL SKLASFIAGY QIFQITLTRS YNVSNLIEDL
3110 3120 3130 3140 3150
KNLYKVAGAE GKGITFIFTD NEIKDEAFLE YLNNLLSSGE ISNLFARDEM
3160 3170 3180 3190 3200
DEITQGLISV MKRELPRHPP TFDNLYEYFI TRSRKNLHVV LCFSPVGEKF
3210 3220 3230 3240 3250
RARSLKFPGL ISGCTMDWFS RWPKEALIAV ASYFLLDYNI VCSIETKRHV
3260 3270 3280 3290 3300
VETMGLFHDM VSESCENYFQ RYRRRAHVTP KSYLSFINGY KSIYTDKVKY
3310 3320 3330 3340 3350
INEQAERMNI GLDKLMEASE SVAKLSQDLA VKEKELAVAS IKADEVLAEV
3360 3370 3380 3390 3400
TVSAQASAKV KNEVQEVKDK AQKIVDEIDS EKVKAETKLE AAKPALEEAE
3410 3420 3430 3440 3450
AALNTIKPND IATVRKLAKP PHLIMRIMDC VLLLFQKKID PVTMDPEKPC
3460 3470 3480 3490 3500
CKPSWGESLK LMSATGFLFS LQQFPKDTIN EETVELLQPY FNMDDYTFES
3510 3520 3530 3540 3550
AKKVCGNVAG LLSWTLAMVI FYGINREVLP LKANLAKQEG RLAVANVELG
3560 3570 3580 3590 3600
KAQALLDEKQ AELDKVQAKF DAAMKEKMDL LNDADMCRKK MQAASTLIDG
3610 3620 3630 3640 3650
LSGEKVRWTQ QSKEFKTQIN RLVGDVLLCT GFLSYLGPFN QIFRNYLLKD
3660 3670 3680 3690 3700
QWELELKARK IPFTENLNLI AMLVDPPTIG EWGLQGLPGD DLSIQNGIIV
3710 3720 3730 3740 3750
TKATRYPLLI DPQTQGKTWI KSKEKENDLQ VTSLNHKYFR THLEDSLSLG
3760 3770 3780 3790 3800
RPLLIEDIRE ELDPALDNVL EKNFIKSGTA FKVKVGDKEC DIMDTFKLYI
3810 3820 3830 3840 3850
TTKLPNPAFT PEINAKTSVI DFTVTMKGLE NQLLRRVILT EKQELESERV
3860 3870 3880 3890 3900
KLLEDVTFNK RKMKELEDNL LYKLSATKGS LVDDESLIGV LRITKQTAAE
3910 3920 3930 3940 3950
VSEKLHVAAE TEIKINTAQE EFRPAATRGS ILYFLITEMS MVNIMYQTSL
3960 3970 3980 3990 4000
AQFLKLFDQS MARSEKSPLP QKRITNIIEY LTYEVFTYSV RGLYENHKFL
4010 4020 4030 4040 4050
FVLLMTLKID LQRGTVKHKE FQALIKGGAA LDLKACPPKP FRWILDMTWL
4060 4070 4080 4090 4100
NLVELSKLPQ FAEIMNQISR NEKGWKNWFD KDAPEEEIIP DGYNDSLDTC
4110 4120 4130 4140 4150
RKLLLIRSWC PDRTVFQARK YIADSLEEKY TEPVILNLEK TWEESDTHTP
4160 4170 4180 4190 4200
LICFLSMGSD PTIQIDALAK KLKLECRTIS MGQGQEVHAR KLIQLSMQQG
4210 4220 4230 4240 4250
GWVLLQNCHL GLEFMEELLE MLMVTETTED SFRVWITTEP HDRFPITLLQ
4260 4270 4280 4290 4300
TSIKFTNEPP QGVRAGLKRT FAGINQDLLD ISNLPMWKPM LYTVAFLHST
4310 4320 4330 4340 4350
VQERRKFGPL GWNIPYEFNS ADFSASVQFI QNHLDECDIK KGVSWSTVRY
4360 4370 4380 4390 4400
MIGEVQYGGR VTDDFDKRLL NCFARVWFSE KMFEPSFCFY TGYKIPICKT
4410 4420 4430 4440 4450
LDQYFEFIQS LPSLDNPEVF GLHPNADITY QSNTASDVLE TITNIQPKES
4460 4470 4480 4490 4500
GGGVGETREA IVYRLSEDML SKLPPNYVPH EVKARLMKMG HLNSMNIFLR
4510 4520 4530 4540 4550
QEIDRMQKVI SILRSSLSDL KLAIEGTIIM SENLRDALDN MYDARIPQLW
4560 4570 4580 4590 4600
KRVSWDSSTL GFWFTELLER NAQFSTWIFE GRPNVFWMTG FFNPQGFLTA
4610 4620 4630 4640 4650
MRQEVTRAHK GWALDTVTIH NEVLRQTKEE IITPPAEGVY IYGLYMDGAS
4660 4670 4680 4690 4700
WDRRNGKLTE STPKVLFTQL PVLHIFAINS TAPKDPKLYV CPIYKKPRRT
4710 4720 4730
DLTFITVVYL RTVLSPDHWI LRGVALLCDI K
Length:4,731
Mass (Da):541,238
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37711771223CEC0A
GO
Isoform 2 (identifier: Q91XQ0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     4200-4202: GGW → VCN
     4203-4731: Missing.

Note: May be due to an intron retention.Curated
Show »
Length:4,202
Mass (Da):480,155
Checksum:iC46E40CEBA790E1C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A494BBC2A0A494BBC2_MOUSE
Dynein heavy chain 8, axonemal
Dnah8
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494B992A0A494B992_MOUSE
Dynein heavy chain 8, axonemal
Dnah8
288Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494BAN8A0A494BAN8_MOUSE
Dynein heavy chain 8, axonemal
Dnah8
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE21572 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti127 – 128GI → RL in AAK60623 (PubMed:12297094).Curated2
Sequence conflicti127 – 128GI → RL in AAK60624 (PubMed:12297094).Curated2
Sequence conflicti127 – 128GI → RL in AAK60632 (PubMed:12297094).Curated2
Sequence conflicti424R → C in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti424R → C in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti424R → C in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti567C → R in AAK60621 (PubMed:12297094).Curated1
Sequence conflicti567C → R in AAK60622 (PubMed:12297094).Curated1
Sequence conflicti813T → R in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti813T → R in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti813T → R in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti963D → N in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti963D → N in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti963D → N in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti982T → A in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti982T → A in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti982T → A in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1051E → K in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1051E → K in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1051E → K in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1291K → E in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1291K → E in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1291K → E in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1421V → I in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1421V → I in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1421V → I in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK60621 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK60622 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1429K → Q in AAK18309 (PubMed:12297094).Curated1
Sequence conflicti1437N → S in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1437N → S in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1437N → S in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1463V → E in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1463V → E in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1463V → E in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1566A → G in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1566A → G in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1566A → G in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti1569D → N in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti1569D → N in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti1569D → N in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti2060L → F in CAB06071 (PubMed:9373155).Curated1
Sequence conflicti2157Y → N in CAB06071 (PubMed:9373155).Curated1
Sequence conflicti2164K → R in CAB06071 (PubMed:9373155).Curated1
Sequence conflicti2167K → T in CAB06071 (PubMed:9373155).Curated1
Sequence conflicti2224V → A in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti2224V → A in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti2224V → A in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti2264N → A in CAB06071 (PubMed:9373155).Curated1
Sequence conflicti3408P → T in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti3408P → T in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti3408P → T in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti3893I → V in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti3893I → V in AAK60624 (PubMed:12297094).Curated1
Sequence conflicti3893I → V in AAK60632 (PubMed:12297094).Curated1
Sequence conflicti4229E → K in AAK60623 (PubMed:12297094).Curated1
Sequence conflicti4310L → W in BAE21572 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0226164200 – 4202GGW → VCN in isoform 2. 1 Publication3
Alternative sequenceiVSP_0226174203 – 4731Missing in isoform 2. 1 PublicationAdd BLAST529

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF356520 mRNA Translation: AAK60621.1
AF356521 mRNA Translation: AAK60622.1
AF356522 mRNA Translation: AAK60623.1
AF356523 mRNA Translation: AAK60624.1
AF363577 mRNA Translation: AAK60632.1
AF342999 Genomic DNA Translation: AAK18309.1
AC165951 Genomic DNA No translation available.
AC165962 Genomic DNA No translation available.
AC166166 Genomic DNA No translation available.
AC174471 Genomic DNA No translation available.
AF117305 mRNA Translation: AAF20213.1
Z83817 mRNA Translation: CAB06071.1
AK133238 mRNA Translation: BAE21572.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37541.1 [Q91XQ0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_038839.2, NM_013811.3 [Q91XQ0-1]
XP_006523651.1, XM_006523588.2 [Q91XQ0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000170651; ENSMUSP00000127878; ENSMUSG00000033826 [Q91XQ0-1]
ENSMUST00000235390; ENSMUSP00000158051; ENSMUSG00000033826 [Q91XQ0-1]
ENSMUST00000236140; ENSMUSP00000157469; ENSMUSG00000033826 [Q91XQ0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
13417

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:13417

UCSC genome browser

More...
UCSCi
uc008bua.1, mouse [Q91XQ0-2]
uc008bub.1, mouse [Q91XQ0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF356520 mRNA Translation: AAK60621.1
AF356521 mRNA Translation: AAK60622.1
AF356522 mRNA Translation: AAK60623.1
AF356523 mRNA Translation: AAK60624.1
AF363577 mRNA Translation: AAK60632.1
AF342999 Genomic DNA Translation: AAK18309.1
AC165951 Genomic DNA No translation available.
AC165962 Genomic DNA No translation available.
AC166166 Genomic DNA No translation available.
AC174471 Genomic DNA No translation available.
AF117305 mRNA Translation: AAF20213.1
Z83817 mRNA Translation: CAB06071.1
AK133238 mRNA Translation: BAE21572.1 Different initiation.
CCDSiCCDS37541.1 [Q91XQ0-1]
RefSeqiNP_038839.2, NM_013811.3 [Q91XQ0-1]
XP_006523651.1, XM_006523588.2 [Q91XQ0-1]

3D structure databases

SMRiQ91XQ0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi199249, 1 interactor
STRINGi10090.ENSMUSP00000127878

PTM databases

iPTMnetiQ91XQ0
PhosphoSitePlusiQ91XQ0

Proteomic databases

PaxDbiQ91XQ0
PRIDEiQ91XQ0

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29878, 52 antibodies

Genome annotation databases

EnsembliENSMUST00000170651; ENSMUSP00000127878; ENSMUSG00000033826 [Q91XQ0-1]
ENSMUST00000235390; ENSMUSP00000158051; ENSMUSG00000033826 [Q91XQ0-1]
ENSMUST00000236140; ENSMUSP00000157469; ENSMUSG00000033826 [Q91XQ0-1]
GeneIDi13417
KEGGimmu:13417
UCSCiuc008bua.1, mouse [Q91XQ0-2]
uc008bub.1, mouse [Q91XQ0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1769
MGIiMGI:107714, Dnah8

Phylogenomic databases

eggNOGiKOG3595, Eukaryota
GeneTreeiENSGT00940000158992
HOGENOMiCLU_000038_9_1_1
InParanoidiQ91XQ0
KOiK10408
OMAiCAKIFKG
OrthoDBi6295at2759
TreeFamiTF316836

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
13417, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Dnah8, mouse

Protein Ontology

More...
PROi
PR:Q91XQ0
RNActiQ91XQ0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000033826, Expressed in spermatocyte and 96 other tissues
ExpressionAtlasiQ91XQ0, baseline and differential
GenevisibleiQ91XQ0, MM

Family and domain databases

Gene3Di1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR041589, DNAH3_AAA_lid_1
IPR042228, Dynein_2_C
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041466, Dynein_AAA5_ext
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013594, Dynein_heavy_dom-1
IPR013602, Dynein_heavy_dom-2
IPR027417, P-loop_NTPase
PANTHERiPTHR10676, PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 1 hit
PF17857, AAA_lid_1, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08385, DHC_N1, 1 hit
PF08393, DHC_N2, 1 hit
PF17852, Dynein_AAA_lid, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 3 hits
SUPFAMiSSF52540, SSF52540, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDYH8_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91XQ0
Secondary accession number(s): E9Q010
, O08830, Q3V0D2, Q91V63, Q91XP8, Q91XP9, Q99MH8, Q9QY72
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 27, 2011
Last modified: August 12, 2020
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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