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Entry version 146 (08 May 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Formimidoyltransferase-cyclodeaminase

Gene

Ftcd

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity).By similarity
Binds and promotes bundling of vimentin filaments originating from the Golgi.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pyridoxal 5'-phosphateBy similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: L-histidine degradation into L-glutamate

This protein is involved in step 1 of the subpathway that synthesizes L-glutamate from N-formimidoyl-L-glutamate (transferase route).
Proteins known to be involved in this subpathway in this organism are:
  1. Formimidoyltransferase-cyclodeaminase (Ftcd)
This subpathway is part of the pathway L-histidine degradation into L-glutamate, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-glutamate from N-formimidoyl-L-glutamate (transferase route), the pathway L-histidine degradation into L-glutamate and in Amino-acid degradation.

Pathwayi: tetrahydrofolate interconversion

This protein is involved in the pathway tetrahydrofolate interconversion, which is part of One-carbon metabolism.
View all proteins of this organism that are known to be involved in the pathway tetrahydrofolate interconversion and in One-carbon metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei82For formimidoyltransferase activityBy similarity1
Active sitei412For cyclodeaminase activityBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyase, Multifunctional enzyme, Transferase
Biological processHistidine metabolism
LigandFolate-binding, Pyridoxal phosphate

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-70921 Histidine catabolism

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00193
UPA00379;UER00555

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Formimidoyltransferase-cyclodeaminase
Alternative name(s):
Formiminotransferase-cyclodeaminase
Short name:
FTCD
Including the following 2 domains:
Glutamate formimidoyltransferase (EC:2.1.2.5)
Alternative name(s):
Glutamate formiminotransferase
Glutamate formyltransferase
Formimidoyltetrahydrofolate cyclodeaminase (EC:4.3.1.4)
Alternative name(s):
Formiminotetrahydrofolate cyclodeaminase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ftcd
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1339962 Ftcd

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Golgi apparatus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000873601 – 541Formimidoyltransferase-cyclodeaminaseAdd BLAST541

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei520PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q91XD4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q91XD4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q91XD4

PeptideAtlas

More...
PeptideAtlasi
Q91XD4

PRoteomics IDEntifications database

More...
PRIDEi
Q91XD4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q91XD4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q91XD4

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q91XD4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000001155 Expressed in 54 organ(s), highest expression level in liver

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q91XD4 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
199754, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q91XD4, 2 interactors

Molecular INTeraction database

More...
MINTi
Q91XD4

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000001183

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91XD4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 181Formiminotransferase N-subdomainBy similarityAdd BLAST181
Regioni163 – 172Folate bindingSequence analysis10
Regioni182 – 326Formiminotransferase C-subdomainBy similarityAdd BLAST145
Regioni327 – 334LinkerBy similarity8
Regioni335 – 541Cyclodeaminase/cyclohydrolaseBy similarityAdd BLAST207

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.Curated
In the N-terminal section; belongs to the formiminotransferase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IERX Eukaryota
COG3404 LUCA
COG3643 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005581

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006949

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q91XD4

KEGG Orthology (KO)

More...
KOi
K13990

Identification of Orthologs from Complete Genome Data

More...
OMAi
YGKRQFE

Database of Orthologous Groups

More...
OrthoDBi
1063278at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q91XD4

TreeFam database of animal gene trees

More...
TreeFami
TF333892

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.680, 1 hit
3.30.70.670, 1 hit
3.30.990.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007044 Cyclodeamin/CycHdrlase
IPR013802 Formiminotransferase_C
IPR037070 Formiminotransferase_C_sf
IPR004227 Formiminotransferase_cat
IPR012886 Formiminotransferase_N
IPR037064 Formiminotransferase_N_sf
IPR022384 FormiminoTrfase_cat_dom_sf
IPR036178 Formintransfe-cycloase-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02971 FTCD, 1 hit
PF04961 FTCD_C, 1 hit
PF07837 FTCD_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01221 FTCD, 1 hit
SM01222 FTCD_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101262 SSF101262, 1 hit
SSF55116 SSF55116, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02024 FtcD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q91XD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQLVECVPN FSEGNNQEVI DAISRAISQT PGCVLLDVDA GPSTNRTVYT
60 70 80 90 100
FVGQPECVVE GALHAARTAS QLIDMSKHKG EHPRMGALDV CPFIPVRGVS
110 120 130 140 150
MEECVLCAKA FGQRLAEELN VPVYLYGEAA QTPSRQTLPA IRAGEYEALP
160 170 180 190 200
EKLKQAEWVP DFGPSSFVPS WGATVTGARK FLIAFNINLL STKEQAHRIA
210 220 230 240 250
LNLREQGRGK DQPGRLKKVQ GIGWYLEEKN LAQVSTNLLD FEVTALHTVF
260 270 280 290 300
EEARREAQEL NLPVVGSQLV GLVPLKALLD AAAFYCDKEK LFVLEEEHRI
310 320 330 340 350
RLVVNRLGLD SLAPFDPKER IIEYLVPDSG PEQSLLDTSL RGFVREVGAR
360 370 380 390 400
SAAPGGGSVA AAVAALGAAL ASMVGQMTYG RRQFDHLDST MRRLIPPFHA
410 420 430 440 450
ASAQLTSLVD ADARAFAACL EAIKLPKNTP EERDRRACAL QEGLRQAVAV
460 470 480 490 500
PLKLAETVSQ LWPALQELAH CGNLSCLSDL QVAAKALETG VFGAYFNVLI
510 520 530 540
NLKDMTDDVF KEKTHHRISS LLQEAKTQAA LVLGSLEARK E
Length:541
Mass (Da):58,939
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i988DDAC3847F5BC3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC010813 mRNA Translation: AAH10813.1
BC024078 mRNA Translation: AAH24078.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS23950.1

NCBI Reference Sequences

More...
RefSeqi
NP_543121.1, NM_080845.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000001183; ENSMUSP00000001183; ENSMUSG00000001155

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
14317

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:14317

UCSC genome browser

More...
UCSCi
uc007fut.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC010813 mRNA Translation: AAH10813.1
BC024078 mRNA Translation: AAH24078.1
CCDSiCCDS23950.1
RefSeqiNP_543121.1, NM_080845.2

3D structure databases

SMRiQ91XD4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi199754, 1 interactor
IntActiQ91XD4, 2 interactors
MINTiQ91XD4
STRINGi10090.ENSMUSP00000001183

PTM databases

iPTMnetiQ91XD4
PhosphoSitePlusiQ91XD4
SwissPalmiQ91XD4

Proteomic databases

jPOSTiQ91XD4
MaxQBiQ91XD4
PaxDbiQ91XD4
PeptideAtlasiQ91XD4
PRIDEiQ91XD4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000001183; ENSMUSP00000001183; ENSMUSG00000001155
GeneIDi14317
KEGGimmu:14317
UCSCiuc007fut.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10841
MGIiMGI:1339962 Ftcd

Phylogenomic databases

eggNOGiENOG410IERX Eukaryota
COG3404 LUCA
COG3643 LUCA
GeneTreeiENSGT00390000005581
HOGENOMiHOG000006949
InParanoidiQ91XD4
KOiK13990
OMAiYGKRQFE
OrthoDBi1063278at2759
PhylomeDBiQ91XD4
TreeFamiTF333892

Enzyme and pathway databases

UniPathwayiUPA00193
UPA00379;UER00555
ReactomeiR-MMU-70921 Histidine catabolism

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q91XD4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000001155 Expressed in 54 organ(s), highest expression level in liver
GenevisibleiQ91XD4 MM

Family and domain databases

Gene3Di1.20.120.680, 1 hit
3.30.70.670, 1 hit
3.30.990.10, 1 hit
InterProiView protein in InterPro
IPR007044 Cyclodeamin/CycHdrlase
IPR013802 Formiminotransferase_C
IPR037070 Formiminotransferase_C_sf
IPR004227 Formiminotransferase_cat
IPR012886 Formiminotransferase_N
IPR037064 Formiminotransferase_N_sf
IPR022384 FormiminoTrfase_cat_dom_sf
IPR036178 Formintransfe-cycloase-like_sf
PfamiView protein in Pfam
PF02971 FTCD, 1 hit
PF04961 FTCD_C, 1 hit
PF07837 FTCD_N, 1 hit
SMARTiView protein in SMART
SM01221 FTCD, 1 hit
SM01222 FTCD_N, 1 hit
SUPFAMiSSF101262 SSF101262, 1 hit
SSF55116 SSF55116, 2 hits
TIGRFAMsiTIGR02024 FtcD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFTCD_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91XD4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: December 1, 2001
Last modified: May 8, 2019
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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