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Protein

Protein YIF1A

Gene

Yif1a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Possible role in transport between endoplasmic reticulum and Golgi.By similarity

GO - Biological processi

  • ER to Golgi vesicle-mediated transport Source: GO_Central
  • protein transport Source: UniProtKB-KW

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIF1A
Alternative name(s):
YIP1-interacting factor homolog A
Gene namesi
Name:Yif1a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1915340 Yif1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 138CytoplasmicSequence analysisAdd BLAST137
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 174LumenalCuratedAdd BLAST15
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21
Topological domaini196 – 203CytoplasmicCurated8
Transmembranei204 – 226HelicalSequence analysisAdd BLAST23
Topological domaini227 – 229LumenalCurated3
Transmembranei230 – 249HelicalSequence analysisAdd BLAST20
Topological domaini250 – 271CytoplasmicCuratedAdd BLAST22
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002332762 – 293Protein YIF1AAdd BLAST292

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei12PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ91XB7
MaxQBiQ91XB7
PaxDbiQ91XB7
PeptideAtlasiQ91XB7
PRIDEiQ91XB7

PTM databases

PhosphoSitePlusiQ91XB7

Expressioni

Gene expression databases

BgeeiENSMUSG00000024875 Expressed in 287 organ(s), highest expression level in internal carotid artery
CleanExiMM_YIF1A
GenevisibleiQ91XB7 MM

Interactioni

Subunit structurei

Interacts with YIPF5.By similarity

Protein-protein interaction databases

IntActiQ91XB7, 2 interactors
MINTiQ91XB7
STRINGi10090.ENSMUSP00000025811

Structurei

3D structure databases

ProteinModelPortaliQ91XB7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3094 Eukaryota
COG5197 LUCA
GeneTreeiENSGT00390000009423
HOGENOMiHOG000234333
HOVERGENiHBG053252
InParanoidiQ91XB7
KOiK20362
OMAiANMAMAY
OrthoDBiEOG091G0H35
PhylomeDBiQ91XB7
TreeFamiTF314528

Family and domain databases

InterProiView protein in InterPro
IPR005578 Yif1_fam
PANTHERiPTHR14083 PTHR14083, 1 hit
PfamiView protein in Pfam
PF03878 YIF1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q91XB7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAYHSAYGVH GSKHRTRAAP DPPPLFDDTS GGYSSQLGGY PAPGADVAFS
60 70 80 90 100
VNNLLGDPVA NMAMAYGTSI ASQGKDIVHK ELHRFVSVNK LKYFFAVDTA
110 120 130 140 150
YVAKKLGLLV FPYTHQNWKM QYSHDVPLPP RKDLNAPDLY IPTMAFITYV
160 170 180 190 200
LLAGMALGIQ QRFSPEVLGL CASTALVWVF MEVLALLLGL YLATVRSELS
210 220 230 240 250
TFHLLAYSGY KYVGMILSVL TGLLFGSDGY YVALAWTSSA LMYFIVRSLR
260 270 280 290
TAASGPDSMG GPAPRQRLQL YLTLGAAAFQ PLIIYWLTFH LVR
Length:293
Mass (Da):32,134
Last modified:December 1, 2001 - v1
Checksum:iC8FB798A9A235577
GO

Sequence cautioni

The sequence BAB21972 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002259 mRNA Translation: BAB21972.2 Different initiation.
AK077329 mRNA Translation: BAC36754.1
AK160409 mRNA Translation: BAE35776.1
BC011117 mRNA Translation: AAH11117.1
CCDSiCCDS29450.1
RefSeqiNP_080829.1, NM_026553.4
UniGeneiMm.44202

Genome annotation databases

EnsembliENSMUST00000025811; ENSMUSP00000025811; ENSMUSG00000024875
GeneIDi68090
KEGGimmu:68090
UCSCiuc008gcd.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002259 mRNA Translation: BAB21972.2 Different initiation.
AK077329 mRNA Translation: BAC36754.1
AK160409 mRNA Translation: BAE35776.1
BC011117 mRNA Translation: AAH11117.1
CCDSiCCDS29450.1
RefSeqiNP_080829.1, NM_026553.4
UniGeneiMm.44202

3D structure databases

ProteinModelPortaliQ91XB7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ91XB7, 2 interactors
MINTiQ91XB7
STRINGi10090.ENSMUSP00000025811

PTM databases

PhosphoSitePlusiQ91XB7

Proteomic databases

EPDiQ91XB7
MaxQBiQ91XB7
PaxDbiQ91XB7
PeptideAtlasiQ91XB7
PRIDEiQ91XB7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025811; ENSMUSP00000025811; ENSMUSG00000024875
GeneIDi68090
KEGGimmu:68090
UCSCiuc008gcd.2 mouse

Organism-specific databases

CTDi10897
MGIiMGI:1915340 Yif1a

Phylogenomic databases

eggNOGiKOG3094 Eukaryota
COG5197 LUCA
GeneTreeiENSGT00390000009423
HOGENOMiHOG000234333
HOVERGENiHBG053252
InParanoidiQ91XB7
KOiK20362
OMAiANMAMAY
OrthoDBiEOG091G0H35
PhylomeDBiQ91XB7
TreeFamiTF314528

Miscellaneous databases

ChiTaRSiYif1a mouse
PROiPR:Q91XB7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024875 Expressed in 287 organ(s), highest expression level in internal carotid artery
CleanExiMM_YIF1A
GenevisibleiQ91XB7 MM

Family and domain databases

InterProiView protein in InterPro
IPR005578 Yif1_fam
PANTHERiPTHR14083 PTHR14083, 1 hit
PfamiView protein in Pfam
PF03878 YIF1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiYIF1A_MOUSE
AccessioniPrimary (citable) accession number: Q91XB7
Secondary accession number(s): Q9CWB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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