Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Golgi membrane protein 1

Gene

Golm1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Unknown. Cellular response protein to viral infection (By similarity).By similarity

Caution

It is uncertain whether Met-1 or Met-2 is the initiator.Curated

GO - Biological processi

  • nucleus organization Source: MGI
  • regulation of lipid metabolic process Source: MGI

Enzyme and pathway databases

ReactomeiR-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Names & Taxonomyi

Protein namesi
Recommended name:
Golgi membrane protein 1
Alternative name(s):
Golgi membrane protein GP73
Golgi phosphoprotein 2
Gene namesi
Name:Golm1
Synonyms:Golph2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1917329 Golm1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 12CytoplasmicSequence analysisAdd BLAST12
Transmembranei13 – 35Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST23
Topological domaini36 – 393LumenalSequence analysisAdd BLAST358

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000875531 – 393Golgi membrane protein 1Add BLAST393

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Glycosylationi109N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi144N-linked (GlcNAc...) asparagine1 Publication1
Modified residuei187PhosphoserineBy similarity1
Glycosylationi227N-linked (GlcNAc...) asparagineSequence analysis1

Post-translational modificationi

Phosphorylation sites are present in the extracellular medium.By similarity

Keywords - PTMi

Acetylation, Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ91XA2
MaxQBiQ91XA2
PaxDbiQ91XA2
PRIDEiQ91XA2

PTM databases

iPTMnetiQ91XA2
PhosphoSitePlusiQ91XA2

Expressioni

Inductioni

Up-regulated in response to viral infection.By similarity

Gene expression databases

BgeeiENSMUSG00000021556 Expressed in 284 organ(s), highest expression level in epithelium of stomach
CleanExiMM_GOLM1
GenevisibleiQ91XA2 MM

Interactioni

Subunit structurei

Interacts with DYM.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022039

Structurei

3D structure databases

ProteinModelPortaliQ91XA2
SMRiQ91XA2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili40 – 183Sequence analysisAdd BLAST144

Sequence similaritiesi

Belongs to the GOLM1/CASC4 family.Curated

Keywords - Domaini

Coiled coil, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IKCK Eukaryota
ENOG4111ZGQ LUCA
GeneTreeiENSGT00530000063675
HOGENOMiHOG000065682
HOVERGENiHBG062332
InParanoidiQ91XA2
OMAiQREKRNH
OrthoDBiEOG091G0D2S
TreeFamiTF331127

Family and domain databases

InterProiView protein in InterPro
IPR026143 GOLM1
IPR026139 GOLM1/CASC4
PANTHERiPTHR15896 PTHR15896, 1 hit
PTHR15896:SF8 PTHR15896:SF8, 1 hit
PRINTSiPR02084 GOLM1CASC4

Sequencei

Sequence statusi: Complete.

Q91XA2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMGLGNGRRS MKSPPLILAA LVACVIVLGF NYWIASSRSV ELQTRIVELE
60 70 80 90 100
GRVRRAAAER GAVELKKNEF QGELQKQREQ LDRIQSSHSF QLENVNKLHQ
110 120 130 140 150
DEKAVLVNNI TTGEKLIRDL QDQLKALQRS YSSLQQDIFQ FQKNQTSLEK
160 170 180 190 200
KFSYDLNQCI SQMTEVKEQC DERIEEVIRK RNEAPGSRDL AETNNQHQQA
210 220 230 240 250
LKPQPKLQEE VPSEEQMPQE KGDVPRNKSQ IPAPNSESLG LKPQVQNEET
260 270 280 290 300
NEIQAVGEEH QQASIQGQAV ADGTRVGAEK LDQHTQLPAG LLARPEEDSQ
310 320 330 340 350
YPEREQLVIR DRQEQQRASE EGGGQKNPGD EYDMDENEAE SEREKQAALA
360 370 380 390
GNDRNINVLN ADAQKRGIIN VPVGSERQSH ILNQVGIHIP QQA
Length:393
Mass (Da):44,326
Last modified:October 3, 2012 - v2
Checksum:iB19881050CC5AD55
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti319S → A in AAH11152 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134869 Genomic DNA No translation available.
CH466546 Genomic DNA Translation: EDL41283.1
CH466546 Genomic DNA Translation: EDL41284.1
BC011152 mRNA Translation: AAH11152.1
CCDSiCCDS26576.1
RefSeqiNP_001030294.1, NM_001035122.2
NP_081583.3, NM_027307.4
UniGeneiMm.171335

Genome annotation databases

EnsembliENSMUST00000022039; ENSMUSP00000022039; ENSMUSG00000021556
ENSMUST00000095739; ENSMUSP00000093410; ENSMUSG00000021556
GeneIDi105348
KEGGimmu:105348
UCSCiuc007quw.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134869 Genomic DNA No translation available.
CH466546 Genomic DNA Translation: EDL41283.1
CH466546 Genomic DNA Translation: EDL41284.1
BC011152 mRNA Translation: AAH11152.1
CCDSiCCDS26576.1
RefSeqiNP_001030294.1, NM_001035122.2
NP_081583.3, NM_027307.4
UniGeneiMm.171335

3D structure databases

ProteinModelPortaliQ91XA2
SMRiQ91XA2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022039

PTM databases

iPTMnetiQ91XA2
PhosphoSitePlusiQ91XA2

Proteomic databases

EPDiQ91XA2
MaxQBiQ91XA2
PaxDbiQ91XA2
PRIDEiQ91XA2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022039; ENSMUSP00000022039; ENSMUSG00000021556
ENSMUST00000095739; ENSMUSP00000093410; ENSMUSG00000021556
GeneIDi105348
KEGGimmu:105348
UCSCiuc007quw.1 mouse

Organism-specific databases

CTDi51280
MGIiMGI:1917329 Golm1

Phylogenomic databases

eggNOGiENOG410IKCK Eukaryota
ENOG4111ZGQ LUCA
GeneTreeiENSGT00530000063675
HOGENOMiHOG000065682
HOVERGENiHBG062332
InParanoidiQ91XA2
OMAiQREKRNH
OrthoDBiEOG091G0D2S
TreeFamiTF331127

Enzyme and pathway databases

ReactomeiR-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Miscellaneous databases

ChiTaRSiGolm1 mouse
PROiPR:Q91XA2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021556 Expressed in 284 organ(s), highest expression level in epithelium of stomach
CleanExiMM_GOLM1
GenevisibleiQ91XA2 MM

Family and domain databases

InterProiView protein in InterPro
IPR026143 GOLM1
IPR026139 GOLM1/CASC4
PANTHERiPTHR15896 PTHR15896, 1 hit
PTHR15896:SF8 PTHR15896:SF8, 1 hit
PRINTSiPR02084 GOLM1CASC4
ProtoNetiSearch...

Entry informationi

Entry nameiGOLM1_MOUSE
AccessioniPrimary (citable) accession number: Q91XA2
Secondary accession number(s): G3X8U4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 3, 2012
Last modified: November 7, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again