UniProtKB - Q91XA2 (GOLM1_MOUSE)
Protein
Golgi membrane protein 1
Gene
Golm1
Organism
Mus musculus (Mouse)
Status
Functioni
Unknown. Cellular response protein to viral infection.By similarity
Caution
It is uncertain whether Met-1 or Met-2 is the initiator.Curated
GO - Biological processi
- nucleus organization Source: MGI
- regulation of lipid metabolic process Source: MGI
Enzyme and pathway databases
Reactomei | R-MMU-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-MMU-8957275, Post-translational protein phosphorylation |
Names & Taxonomyi
Protein namesi | Recommended name: Golgi membrane protein 1Alternative name(s): Golgi membrane protein GP73 Golgi phosphoprotein 2 |
Gene namesi | Name:Golm1 Synonyms:Golph2 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1917329, Golm1 |
Subcellular locationi
Golgi apparatus
- cis-Golgi network membrane By similarity; Single-pass type II membrane protein By similarity
Note: Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.By similarity
Golgi apparatus
- Golgi apparatus Source: MGI
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 12 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 13 – 35 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 23 | |
Topological domaini | 36 – 393 | LumenalSequence analysisAdd BLAST | 358 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000087553 | 1 – 393 | Golgi membrane protein 1Add BLAST | 393 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineBy similarity | 1 | |
Glycosylationi | 109 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 144 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Modified residuei | 187 | PhosphoserineBy similarity | 1 | |
Glycosylationi | 227 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Post-translational modificationi
Glycosylated.By similarity
Phosphorylation sites are present in the extracellular medium.By similarity
Keywords - PTMi
Acetylation, Glycoprotein, PhosphoproteinProteomic databases
CPTACi | non-CPTAC-3916 |
EPDi | Q91XA2 |
jPOSTi | Q91XA2 |
MaxQBi | Q91XA2 |
PaxDbi | Q91XA2 |
PRIDEi | Q91XA2 |
PTM databases
GlyGeni | Q91XA2, 3 sites |
iPTMneti | Q91XA2 |
PhosphoSitePlusi | Q91XA2 |
Expressioni
Inductioni
Up-regulated in response to viral infection.By similarity
Gene expression databases
Bgeei | ENSMUSG00000021556, Expressed in epithelium of stomach and 299 other tissues |
Genevisiblei | Q91XA2, MM |
Interactioni
Subunit structurei
Interacts with DYM.
By similarityProtein-protein interaction databases
STRINGi | 10090.ENSMUSP00000093410 |
Miscellaneous databases
RNActi | Q91XA2, protein |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 40 – 183 | Sequence analysisAdd BLAST | 144 |
Sequence similaritiesi
Belongs to the GOLM family.Curated
Keywords - Domaini
Coiled coil, Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502S080, Eukaryota |
GeneTreei | ENSGT00530000063675 |
HOGENOMi | CLU_055640_0_0_1 |
InParanoidi | Q91XA2 |
OMAi | QREKRNH |
OrthoDBi | 1073183at2759 |
TreeFami | TF331127 |
Family and domain databases
InterProi | View protein in InterPro IPR026143, GOLM1 IPR026139, GOLM1/CASC4 |
PANTHERi | PTHR15896, PTHR15896, 1 hit PTHR15896:SF8, PTHR15896:SF8, 1 hit |
PRINTSi | PR02084, GOLM1CASC4 |
i Sequence
Sequence statusi: Complete.
Q91XA2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMGLGNGRRS MKSPPLILAA LVACVIVLGF NYWIASSRSV ELQTRIVELE
60 70 80 90 100
GRVRRAAAER GAVELKKNEF QGELQKQREQ LDRIQSSHSF QLENVNKLHQ
110 120 130 140 150
DEKAVLVNNI TTGEKLIRDL QDQLKALQRS YSSLQQDIFQ FQKNQTSLEK
160 170 180 190 200
KFSYDLNQCI SQMTEVKEQC DERIEEVIRK RNEAPGSRDL AETNNQHQQA
210 220 230 240 250
LKPQPKLQEE VPSEEQMPQE KGDVPRNKSQ IPAPNSESLG LKPQVQNEET
260 270 280 290 300
NEIQAVGEEH QQASIQGQAV ADGTRVGAEK LDQHTQLPAG LLARPEEDSQ
310 320 330 340 350
YPEREQLVIR DRQEQQRASE EGGGQKNPGD EYDMDENEAE SEREKQAALA
360 370 380 390
GNDRNINVLN ADAQKRGIIN VPVGSERQSH ILNQVGIHIP QQA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 319 | S → A in AAH11152 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC134869 Genomic DNA No translation available. CH466546 Genomic DNA Translation: EDL41283.1 CH466546 Genomic DNA Translation: EDL41284.1 BC011152 mRNA Translation: AAH11152.1 |
CCDSi | CCDS26576.1 |
RefSeqi | NP_001030294.1, NM_001035122.2 NP_081583.3, NM_027307.4 |
Genome annotation databases
Ensembli | ENSMUST00000022039; ENSMUSP00000022039; ENSMUSG00000021556 ENSMUST00000095739; ENSMUSP00000093410; ENSMUSG00000021556 |
GeneIDi | 105348 |
KEGGi | mmu:105348 |
UCSCi | uc007quw.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC134869 Genomic DNA No translation available. CH466546 Genomic DNA Translation: EDL41283.1 CH466546 Genomic DNA Translation: EDL41284.1 BC011152 mRNA Translation: AAH11152.1 |
CCDSi | CCDS26576.1 |
RefSeqi | NP_001030294.1, NM_001035122.2 NP_081583.3, NM_027307.4 |
3D structure databases
SMRi | Q91XA2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000093410 |
PTM databases
GlyGeni | Q91XA2, 3 sites |
iPTMneti | Q91XA2 |
PhosphoSitePlusi | Q91XA2 |
Proteomic databases
CPTACi | non-CPTAC-3916 |
EPDi | Q91XA2 |
jPOSTi | Q91XA2 |
MaxQBi | Q91XA2 |
PaxDbi | Q91XA2 |
PRIDEi | Q91XA2 |
Protocols and materials databases
Antibodypediai | 2449, 694 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000022039; ENSMUSP00000022039; ENSMUSG00000021556 ENSMUST00000095739; ENSMUSP00000093410; ENSMUSG00000021556 |
GeneIDi | 105348 |
KEGGi | mmu:105348 |
UCSCi | uc007quw.1, mouse |
Organism-specific databases
CTDi | 51280 |
MGIi | MGI:1917329, Golm1 |
Phylogenomic databases
eggNOGi | ENOG502S080, Eukaryota |
GeneTreei | ENSGT00530000063675 |
HOGENOMi | CLU_055640_0_0_1 |
InParanoidi | Q91XA2 |
OMAi | QREKRNH |
OrthoDBi | 1073183at2759 |
TreeFami | TF331127 |
Enzyme and pathway databases
Reactomei | R-MMU-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-MMU-8957275, Post-translational protein phosphorylation |
Miscellaneous databases
BioGRID-ORCSi | 105348, 0 hits in 17 CRISPR screens |
ChiTaRSi | Golm1, mouse |
PROi | PR:Q91XA2 |
RNActi | Q91XA2, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000021556, Expressed in epithelium of stomach and 299 other tissues |
Genevisiblei | Q91XA2, MM |
Family and domain databases
InterProi | View protein in InterPro IPR026143, GOLM1 IPR026139, GOLM1/CASC4 |
PANTHERi | PTHR15896, PTHR15896, 1 hit PTHR15896:SF8, PTHR15896:SF8, 1 hit |
PRINTSi | PR02084, GOLM1CASC4 |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GOLM1_MOUSE | |
Accessioni | Q91XA2Primary (citable) accession number: Q91XA2 Secondary accession number(s): G3X8U4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 16, 2004 |
Last sequence update: | October 3, 2012 | |
Last modified: | February 10, 2021 | |
This is version 122 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families