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UniProtKB - Q91X78 (ERLN1_MOUSE)

Entry version 128 (02 Dec 2020)
Sequence version 2 (08 May 2019)
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Protein

Erlin-1

Gene

Erlin1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-382556, ABC-family proteins mediated transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Erlin-1By similarity
Alternative name(s):
Endoplasmic reticulum lipid raft-associated protein 1
Protein KE04 homologCurated
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Short name:
SPFH domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Erlin1Imported
Synonyms:Keo4, Spfh1By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2387613, Erlin1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 7CytoplasmicSequence analysis7
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Topological domaini29 – 348LumenalSequence analysisAdd BLAST320

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000027851 – 348Erlin-1Add BLAST348

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi108N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei269N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q91X78

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q91X78

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q91X78

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q91X78

PeptideAtlas

More...PeptideAtlasi		Q91X78

PRoteomics IDEntifications database

More...PRIDEi		Q91X78

PTM databases

GlyConnect protein glycosylation platform

More...GlyConnecti		2300, 1 N-Linked glycan (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q91X78, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q91X78

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q91X78

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q91X78, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a heteromeric complex with ERLIN2 (By similarity). In complex with ERLIN2, interacts with RNF170 (PubMed:21610068).

Interacts with AMFR and SYVN1 (By similarity).

By similarity1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		230480, 5 interactors

Protein interaction database and analysis system

More...IntActi		Q91X78, 2 interactors

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000129684

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q91X78, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q91X78

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the band 7/mec-2 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2962, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000014666

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q91X78

Identification of Orthologs from Complete Genome Data

More...OMAi		TDQIDEN

Database of Orthologous Groups

More...OrthoDBi		930534at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q91X78

TreeFam database of animal gene trees

More...TreeFami		TF313059

Family and domain databases

Conserved Domains Database

More...CDDi		cd03406, SPFH_like_u3, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001107, Band_7
IPR036013, Band_7/SPFH_dom_sf
IPR033294, Erlin1/2

The PANTHER Classification System

More...PANTHERi		PTHR15351, PTHR15351, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01145, Band_7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00244, PHB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF117892, SSF117892, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q91X78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMTQARLLV AAVVGLVAIL LYASIHKIEE GHLAVYYRGG ALLTSPSGPG 
        60         70         80         90        100
YHIMLPFITT FRSVQTTLQT DEVKNVPCGT SGGVMIYIDR IEVVNMLAPY 
       110        120        130        140        150
AVFDIVRNYT ADYDKTLIFN KIHHELNQFC SAHTLQEVYI ELFDQIDENL 
       160        170        180        190        200
KQALQKDLNT MAPGLTIQAV RVTKPKIPEA IRRNFELMEA EKTKLLIAAQ 
       210        220        230        240        250
KQKVVEKEAE TERKRAVIEA EKIAQVAKIR FQQKVMEKET EKRISEIEDA 
       260        270        280        290        300
AFLAREKAKA DAEYYAAHKY ATSNKHKLTP EYLELKKYQA IASNSKIYFG 
       310        320        330        340 
SNIPSMFVDS SCALKYSDGR TGREDSLPPE EAREPSGESP IQNKENAG
Length:348
Mass (Da):39,182
Last modified:May 8, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3BA4BE035662EC6F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PUH5E9PUH5_MOUSE
Erlin-1
Erlin1
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PZB0E9PZB0_MOUSE
Erlin-1
Erlin1
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6Z6D6F6Z6D6_MOUSE
Erlin-1
Erlin1
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PVM2E9PVM2_MOUSE
Erlin-1
Erlin1
23Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH11220 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAH23849 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti57F → S in AAH23849 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK133557 mRNA Translation: BAE21724.1
AK145990 mRNA Translation: BAE26812.1
AC124693 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41918.1
BC011220 mRNA Translation: AAH11220.1 Different initiation.
BC023849 mRNA Translation: AAH23849.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS29842.2

NCBI Reference Sequences

More...RefSeqi		NP_001157831.1, NM_001164359.1
NP_001157832.1, NM_001164360.1
NP_663477.3, NM_145502.3
XP_006527061.1, XM_006526998.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000071698; ENSMUSP00000071618; ENSMUSG00000025198
ENSMUST00000112028; ENSMUSP00000107659; ENSMUSG00000025198
ENSMUST00000170801; ENSMUSP00000129684; ENSMUSG00000025198

Database of genes from NCBI RefSeq genomes

More...GeneIDi		226144

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:226144

UCSC genome browser

More...UCSCi		uc008hpd.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK133557 mRNA Translation: BAE21724.1
AK145990 mRNA Translation: BAE26812.1
AC124693 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41918.1
BC011220 mRNA Translation: AAH11220.1 Different initiation.
BC023849 mRNA Translation: AAH23849.1 Different initiation.
CCDSiCCDS29842.2
RefSeqiNP_001157831.1, NM_001164359.1
NP_001157832.1, NM_001164360.1
NP_663477.3, NM_145502.3
XP_006527061.1, XM_006526998.3

3D structure databases

SMRiQ91X78
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230480, 5 interactors
IntActiQ91X78, 2 interactors
STRINGi10090.ENSMUSP00000129684

PTM databases

GlyConnecti2300, 1 N-Linked glycan (1 site)
GlyGeniQ91X78, 1 site
iPTMnetiQ91X78
PhosphoSitePlusiQ91X78

Proteomic databases

EPDiQ91X78
jPOSTiQ91X78
MaxQBiQ91X78
PaxDbiQ91X78
PeptideAtlasiQ91X78
PRIDEiQ91X78

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2279, 197 antibodies

Genome annotation databases

EnsembliENSMUST00000071698; ENSMUSP00000071618; ENSMUSG00000025198
ENSMUST00000112028; ENSMUSP00000107659; ENSMUSG00000025198
ENSMUST00000170801; ENSMUSP00000129684; ENSMUSG00000025198
GeneIDi226144
KEGGimmu:226144
UCSCiuc008hpd.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10613
MGIiMGI:2387613, Erlin1

Phylogenomic databases

eggNOGiKOG2962, Eukaryota
GeneTreeiENSGT00390000014666
InParanoidiQ91X78
OMAiTDQIDEN
OrthoDBi930534at2759
PhylomeDBiQ91X78
TreeFamiTF313059

Enzyme and pathway databases

ReactomeiR-MMU-382556, ABC-family proteins mediated transport

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		226144, 1 hit in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Erlin1, mouse

Protein Ontology

More...PROi		PR:Q91X78
RNActiQ91X78, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

ExpressionAtlasiQ91X78, baseline and differential

Family and domain databases

CDDicd03406, SPFH_like_u3, 1 hit
InterProiView protein in InterPro
IPR001107, Band_7
IPR036013, Band_7/SPFH_dom_sf
IPR033294, Erlin1/2
PANTHERiPTHR15351, PTHR15351, 1 hit
PfamiView protein in Pfam
PF01145, Band_7, 1 hit
SMARTiView protein in SMART
SM00244, PHB, 1 hit
SUPFAMiSSF117892, SSF117892, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiERLN1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91X78
Secondary accession number(s): A0A0R4J1G5, Q3UKI9, Q8CIH7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: May 8, 2019
Last modified: December 2, 2020
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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