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Protein

MAL-like protein

Gene

Mall

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • structural constituent of myelin sheath Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
MAL-like protein
Alternative name(s):
Protein BENE
Gene namesi
Name:Mall
Synonyms:Bene
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2385152 Mall

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001568121 – 154MAL-like proteinAdd BLAST154

Proteomic databases

PaxDbiQ91X49
PRIDEiQ91X49

PTM databases

PhosphoSitePlusiQ91X49

Expressioni

Gene expression databases

BgeeiENSMUSG00000027377 Expressed in 106 organ(s), highest expression level in ear
CleanExiMM_MALL
GenevisibleiQ91X49 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028856

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 154MARVELPROSITE-ProRule annotationAdd BLAST131

Sequence similaritiesi

Belongs to the MAL family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWII Eukaryota
ENOG410YQN9 LUCA
GeneTreeiENSGT00730000110762
HOGENOMiHOG000231752
HOVERGENiHBG000925
InParanoidiQ91X49
OMAiFGCWVWI
OrthoDBiEOG091G0OS1
PhylomeDBiQ91X49
TreeFamiTF316174

Family and domain databases

InterProiView protein in InterPro
IPR013295 MAL
IPR008253 Marvel
PfamiView protein in Pfam
PF01284 MARVEL, 1 hit
PRINTSiPR01884 MALPROTEIN
PROSITEiView protein in PROSITE
PS51225 MARVEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q91X49-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASRDTPPAT SYAPPDVPSG VAALFLTIPF AFFLPELVFG FWVWTLVAAT
60 70 80 90 100
HVAYPLLQGW VLYVSLTSFL ISLMFLMSYL FGFYKRFESW RVLDSLYHGT
110 120 130 140 150
TGILYMSASV LQAYATIISE GHNLSHYYIN VAASFFAFLT TLLYILHAFS

IYYH
Length:154
Mass (Da):17,470
Last modified:December 1, 2001 - v1
Checksum:i2783379F6EFB1DE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078971 mRNA Translation: BAC37487.1
AK163867 mRNA Translation: BAE37520.1
BC012256 mRNA Translation: AAH12256.1
CCDSiCCDS16708.1
RefSeqiNP_663507.1, NM_145532.3
UniGeneiMm.133036

Genome annotation databases

EnsembliENSMUST00000028856; ENSMUSP00000028856; ENSMUSG00000027377
GeneIDi228576
KEGGimmu:228576
UCSCiuc008mfx.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078971 mRNA Translation: BAC37487.1
AK163867 mRNA Translation: BAE37520.1
BC012256 mRNA Translation: AAH12256.1
CCDSiCCDS16708.1
RefSeqiNP_663507.1, NM_145532.3
UniGeneiMm.133036

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028856

PTM databases

PhosphoSitePlusiQ91X49

Proteomic databases

PaxDbiQ91X49
PRIDEiQ91X49

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028856; ENSMUSP00000028856; ENSMUSG00000027377
GeneIDi228576
KEGGimmu:228576
UCSCiuc008mfx.1 mouse

Organism-specific databases

CTDi7851
MGIiMGI:2385152 Mall

Phylogenomic databases

eggNOGiENOG410IWII Eukaryota
ENOG410YQN9 LUCA
GeneTreeiENSGT00730000110762
HOGENOMiHOG000231752
HOVERGENiHBG000925
InParanoidiQ91X49
OMAiFGCWVWI
OrthoDBiEOG091G0OS1
PhylomeDBiQ91X49
TreeFamiTF316174

Miscellaneous databases

PROiPR:Q91X49
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027377 Expressed in 106 organ(s), highest expression level in ear
CleanExiMM_MALL
GenevisibleiQ91X49 MM

Family and domain databases

InterProiView protein in InterPro
IPR013295 MAL
IPR008253 Marvel
PfamiView protein in Pfam
PF01284 MARVEL, 1 hit
PRINTSiPR01884 MALPROTEIN
PROSITEiView protein in PROSITE
PS51225 MARVEL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMALL_MOUSE
AccessioniPrimary (citable) accession number: Q91X49
Secondary accession number(s): Q3TQ65
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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