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Protein

SPATS2-like protein

Gene

Spats2l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
SPATS2-like protein
Gene namesi
Name:Spats2l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1914448 Spats2l

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00003077002 – 558SPATS2-like proteinAdd BLAST557

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei120PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ91WJ7
PeptideAtlasiQ91WJ7
PRIDEiQ91WJ7

PTM databases

iPTMnetiQ91WJ7
PhosphoSitePlusiQ91WJ7

Expressioni

Gene expression databases

BgeeiENSMUSG00000038305 Expressed in 267 organ(s), highest expression level in humerus cartilage element
CleanExiMM_2810022L02RIK
ExpressionAtlasiQ91WJ7 baseline and differential
GenevisibleiQ91WJ7 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000133054

Structurei

3D structure databases

ProteinModelPortaliQ91WJ7
SMRiQ91WJ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili279 – 344Sequence analysisAdd BLAST66

Sequence similaritiesi

Belongs to the SPATS2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IJV6 Eukaryota
ENOG410Y9WN LUCA
GeneTreeiENSGT00390000001138
HOGENOMiHOG000013053
HOVERGENiHBG059711
InParanoidiQ91WJ7
PhylomeDBiQ91WJ7

Family and domain databases

InterProiView protein in InterPro
IPR009816 DUF1387
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF07139 DUF1387, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q91WJ7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAELNTHVNI KEKIYAVRSV VPNKSNNEIV LVLQQFDFNV DKAVQAFVDG
60 70 80 90 100
SAIQVLKEWN MTGKKKNNKR KRSKSKQHQG NKDAKDKVER PEVGPLQPQA
110 120 130 140 150
PLVQNGHMNG CEKDSSSPDS TREKLALTPR EKKISILEEP PRAQRGVTEG
160 170 180 190 200
GRLLQQKMSL DGNPRAIHGP SERSDGPQWS AGQPCNPSKP KAKTSPVKSN
210 220 230 240 250
APAAHLEIKP DELAKKRGPN IEKSVKDLQR CTVSLTRYRV MIKEEVDSSV
260 270 280 290 300
KKIKAAFAEL HNCIIDKEVS LMAEMDKVKE EAMDILTARQ KKAEELKRLT
310 320 330 340 350
DLASQMAEMQ LAELRAEIKH FVSERKYDEE LGKAARFSCD IEQLKAQILI
360 370 380 390 400
CGEITHPKNS YSSRTPCSSL LPLLNTHAVA SGKQGNFARK SSGHNKPSEG
410 420 430 440 450
KAANPKMVSG LANTADACHQ TMPTNKQQNG PSSQRRRFNP QYHNRLNGPA
460 470 480 490 500
KSQGGGNEAD PMAKSNSRHE HRRQPHNGFR PKNKGGAKNQ EAPLGTKAPE
510 520 530 540 550
APPHSEKARR RQHAADNLEA RPFRGNVSRV SQCNLCPSRI EVSTEATVLS

VPAVTLVA
Length:558
Mass (Da):61,669
Last modified:October 23, 2007 - v2
Checksum:i7AEBDACFADCC6B69
GO
Isoform 2 (identifier: Q91WJ7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     427-427: Missing.

Note: No experimental confirmation available.
Show »
Length:557
Mass (Da):61,541
Checksum:iBA1B84E75ADEFA09
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PVQ3E9PVQ3_MOUSE
SPATS2-like protein
Spats2l
578Annotation score:
E9PZE9E9PZE9_MOUSE
SPATS2-like protein
Spats2l
488Annotation score:
E9Q7S4E9Q7S4_MOUSE
SPATS2-like protein
Spats2l
450Annotation score:
E9Q5S6E9Q5S6_MOUSE
SPATS2-like protein
Spats2l
270Annotation score:
E9Q106E9Q106_MOUSE
SPATS2-like protein
Spats2l
244Annotation score:
E9Q1C3E9Q1C3_MOUSE
SPATS2-like protein
Spats2l
108Annotation score:
E9Q8P1E9Q8P1_MOUSE
SPATS2-like protein
Spats2l
130Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_028793427Missing in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031266 mRNA Translation: BAC27328.1
AK032169 mRNA Translation: BAC27738.1
BC014764 mRNA Translation: AAH14764.1
BC021879 mRNA Translation: AAH21879.1
BC029001 mRNA Translation: AAH29001.1
CCDSiCCDS48267.1 [Q91WJ7-2]
RefSeqiNP_001158038.1, NM_001164566.1 [Q91WJ7-2]
NP_659131.2, NM_144882.4
XP_006496278.1, XM_006496215.3 [Q91WJ7-1]
XP_006496281.1, XM_006496218.3 [Q91WJ7-1]
UniGeneiMm.159989

Genome annotation databases

EnsembliENSMUST00000169772; ENSMUSP00000132975; ENSMUSG00000038305 [Q91WJ7-2]
ENSMUST00000170139; ENSMUSP00000127598; ENSMUSG00000038305 [Q91WJ7-2]
GeneIDi67198
KEGGimmu:67198
UCSCiuc007bbe.2 mouse [Q91WJ7-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031266 mRNA Translation: BAC27328.1
AK032169 mRNA Translation: BAC27738.1
BC014764 mRNA Translation: AAH14764.1
BC021879 mRNA Translation: AAH21879.1
BC029001 mRNA Translation: AAH29001.1
CCDSiCCDS48267.1 [Q91WJ7-2]
RefSeqiNP_001158038.1, NM_001164566.1 [Q91WJ7-2]
NP_659131.2, NM_144882.4
XP_006496278.1, XM_006496215.3 [Q91WJ7-1]
XP_006496281.1, XM_006496218.3 [Q91WJ7-1]
UniGeneiMm.159989

3D structure databases

ProteinModelPortaliQ91WJ7
SMRiQ91WJ7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000133054

PTM databases

iPTMnetiQ91WJ7
PhosphoSitePlusiQ91WJ7

Proteomic databases

PaxDbiQ91WJ7
PeptideAtlasiQ91WJ7
PRIDEiQ91WJ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000169772; ENSMUSP00000132975; ENSMUSG00000038305 [Q91WJ7-2]
ENSMUST00000170139; ENSMUSP00000127598; ENSMUSG00000038305 [Q91WJ7-2]
GeneIDi67198
KEGGimmu:67198
UCSCiuc007bbe.2 mouse [Q91WJ7-2]

Organism-specific databases

CTDi26010
MGIiMGI:1914448 Spats2l

Phylogenomic databases

eggNOGiENOG410IJV6 Eukaryota
ENOG410Y9WN LUCA
GeneTreeiENSGT00390000001138
HOGENOMiHOG000013053
HOVERGENiHBG059711
InParanoidiQ91WJ7
PhylomeDBiQ91WJ7

Miscellaneous databases

ChiTaRSiSpats2l mouse
PROiPR:Q91WJ7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038305 Expressed in 267 organ(s), highest expression level in humerus cartilage element
CleanExiMM_2810022L02RIK
ExpressionAtlasiQ91WJ7 baseline and differential
GenevisibleiQ91WJ7 MM

Family and domain databases

InterProiView protein in InterPro
IPR009816 DUF1387
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF07139 DUF1387, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSPS2L_MOUSE
AccessioniPrimary (citable) accession number: Q91WJ7
Secondary accession number(s): Q8K322, Q8VC37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: September 12, 2018
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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