Scgn

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Length
Calcium bindingⁱ	25 – 36	1PROSITE-ProRule annotationAdd BLAST	12
Calcium bindingⁱ	71 – 82	2PROSITE-ProRule annotationAdd BLAST	12
Calcium bindingⁱ	118 – 129	3PROSITE-ProRule annotationAdd BLAST	12
Calcium bindingⁱ	162 – 173	4PROSITE-ProRule annotationAdd BLAST	12
Calcium bindingⁱ	210 – 221	5PROSITE-ProRule annotationAdd BLAST	12
Calcium bindingⁱ	254 – 265	6PROSITE-ProRule annotationAdd BLAST	12

GO - Molecular functionⁱ

calcium ion binding Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of cytosolic calcium ion concentration Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Calcium, Metal-binding

Ligand

Calcium, Metal-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Secretagogin
Gene namesⁱ	Name:Scgn
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 13

Organism-specific databases

MGIⁱ	MGI:2384873 Scgn

Keywords - Cellular componentⁱ

Cytoplasm, Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000073637	1 – 276	SecretagoginAdd BLAST		276

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q91WD9
PaxDbⁱ	Q91WD9
PeptideAtlas More...PeptideAtlasⁱ	Q91WD9
PRIDEⁱ	Q91WD9

PTM databases

iPTMnetⁱ	Q91WD9
PhosphoSitePlusⁱ	Q91WD9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000021337 Expressed in 82 organ(s), highest expression level in islet of Langerhans
CleanExⁱ	MM_SCGN
ExpressionAtlasⁱ	Q91WD9 baseline and differential
Genevisibleⁱ	Q91WD9 MM

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000021770

STRINGⁱ

10090.ENSMUSP00000021770

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q91WD9
SMRⁱ	Q91WD9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	12 – 47	EF-hand 1PROSITE-ProRule annotationAdd BLAST	36
Domainⁱ	58 – 93	EF-hand 2PROSITE-ProRule annotationAdd BLAST	36
Domainⁱ	105 – 140	EF-hand 3PROSITE-ProRule annotationAdd BLAST	36
Domainⁱ	149 – 184	EF-hand 4PROSITE-ProRule annotationAdd BLAST	36
Domainⁱ	197 – 232	EF-hand 5PROSITE-ProRule annotationAdd BLAST	36
Domainⁱ	240 – 276	EF-hand 6PROSITE-ProRule annotationAdd BLAST	37

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	KOG0027 Eukaryota COG5126 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000013118
HOGENOMⁱ	HOG000231866
HOVERGENⁱ	HBG000855
InParanoidⁱ	Q91WD9
OMAⁱ	HHKKAIS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0GNH
PhylomeDBⁱ	Q91WD9
TreeFamⁱ	TF325083

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd16178 EFh_HEF_SCGN, 1 hit
InterProⁱ	View protein in InterPro IPR011992 EF-hand-dom_pair IPR018247 EF_Hand_1_Ca_BS IPR002048 EF_hand_dom IPR035798 EFh_SCGN
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13202 EF-hand_5, 1 hit PF13499 EF-hand_7, 1 hit
SMARTⁱ	View protein in SMART SM00054 EFh, 5 hits
SUPFAMⁱ	SSF47473 SSF47473, 2 hits
PROSITEⁱ	View protein in PROSITE PS00018 EF_HAND_1, 4 hits PS50222 EF_HAND_2, 5 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q91WD9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT 
        60         70         80         90        100
EDTLMEENVQ KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL 
       110        120        130        140        150
ETPLDNSVEF MQIWRKYDAD SSGFISAAEL CNFLRDLFLH HKKNISEAEL 
       160        170        180        190        200
EEYTSTMMKI FDKNKDGRLD LNDLARILAL QENFLLQFKM DASSTEERKR 
       210        220        230        240        250
DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL 
       260        270 
RHCDVNKDGK IQKSELALCL GLKINP

Length:276

Mass (Da):32,146

Last modified:December 1, 2001 - v1

Checksum:ⁱDBC86BF7F1CF9987

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A0A286YD29	A0A286YD29_MOUSE		Secretagogin Secretagogin	Scgn	119	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC016093 mRNA Translation: AAH16093.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS26375.1
NCBI Reference Sequences More...RefSeqⁱ	NP_663374.1, NM_145399.1
UniGeneⁱ	Mm.255667

Genome annotation databases

Ensemblⁱ	ENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337
GeneIDⁱ	214189
KEGGⁱ	mmu:214189
UCSC genome browser More...UCSCⁱ	uc007pvk.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q91WD9	Secretagogin		MOUSE		119	UniRef100_Q91WD9

Protein	Similar proteins		Species	Score	Length	Source
Q91WD9	Secretagogin		RAT		276	UniRef90_Q6R556
Secretagogin		MOUSE		119
secretagogin		MESAU		276
UPI00022F46F1		CRIGR		276
UPI00038C55B8		MICOH		276
+5

Protein	Similar proteins		Species	Score	Length	Source
Q91WD9	Secretagogin		HUMAN		276	UniRef50_O76038
Secretagogin		RAT		276
Secretagogin		XENTR		271
Secretagogin		XENLA		271
Secretagogin		PIG		276
+358

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC016093 mRNA Translation: AAH16093.1
CCDSⁱ	CCDS26375.1
RefSeqⁱ	NP_663374.1, NM_145399.1
UniGeneⁱ	Mm.255667

3D structure databases

ProteinModelPortalⁱ	Q91WD9
SMRⁱ	Q91WD9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000021770

STRINGⁱ

10090.ENSMUSP00000021770

PTM databases

iPTMnetⁱ	Q91WD9
PhosphoSitePlusⁱ	Q91WD9

Proteomic databases

MaxQBⁱ	Q91WD9
PaxDbⁱ	Q91WD9
PeptideAtlasⁱ	Q91WD9
PRIDEⁱ	Q91WD9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337
GeneIDⁱ	214189
KEGGⁱ	mmu:214189
UCSCⁱ	uc007pvk.1 mouse

Organism-specific databases

CTDⁱ	10590
MGIⁱ	MGI:2384873 Scgn

Phylogenomic databases

eggNOGⁱ	KOG0027 Eukaryota COG5126 LUCA
GeneTreeⁱ	ENSGT00390000013118
HOGENOMⁱ	HOG000231866
HOVERGENⁱ	HBG000855
InParanoidⁱ	Q91WD9
OMAⁱ	HHKKAIS
OrthoDBⁱ	EOG091G0GNH
PhylomeDBⁱ	Q91WD9
TreeFamⁱ	TF325083

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q91WD9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000021337 Expressed in 82 organ(s), highest expression level in islet of Langerhans
CleanExⁱ	MM_SCGN
ExpressionAtlasⁱ	Q91WD9 baseline and differential
Genevisibleⁱ	Q91WD9 MM

Family and domain databases

CDDⁱ	cd16178 EFh_HEF_SCGN, 1 hit
InterProⁱ	View protein in InterPro IPR011992 EF-hand-dom_pair IPR018247 EF_Hand_1_Ca_BS IPR002048 EF_hand_dom IPR035798 EFh_SCGN
Pfamⁱ	View protein in Pfam PF13202 EF-hand_5, 1 hit PF13499 EF-hand_7, 1 hit
SMARTⁱ	View protein in SMART SM00054 EFh, 5 hits
SUPFAMⁱ	SSF47473 SSF47473, 2 hits
PROSITEⁱ	View protein in PROSITE PS00018 EF_HAND_1, 4 hits PS50222 EF_HAND_2, 5 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SEGN_MOUSE
Accessionⁱ	Q91WD9Primary (citable) accession number: Q91WD9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 22, 2003
	Last sequence update:	December 1, 2001
	Last modified:	October 10, 2018
	This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q91WD9 (SEGN_MOUSE)

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Secretagogin

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Other locations

Cytosol

Extracellular region or secreted

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ