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Protein

Secretagogin

Gene

Scgn

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi25 – 361PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi71 – 822PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi118 – 1293PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi162 – 1734PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi210 – 2215PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi254 – 2656PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Secretagogin
Gene namesi
Name:Scgn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2384873 Scgn

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000736371 – 276SecretagoginAdd BLAST276

Proteomic databases

MaxQBiQ91WD9
PaxDbiQ91WD9
PeptideAtlasiQ91WD9
PRIDEiQ91WD9

PTM databases

iPTMnetiQ91WD9
PhosphoSitePlusiQ91WD9

Expressioni

Gene expression databases

BgeeiENSMUSG00000021337 Expressed in 82 organ(s), highest expression level in islet of Langerhans
CleanExiMM_SCGN
ExpressionAtlasiQ91WD9 baseline and differential
GenevisibleiQ91WD9 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021770

Structurei

3D structure databases

ProteinModelPortaliQ91WD9
SMRiQ91WD9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 47EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini58 – 93EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini105 – 140EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini149 – 184EF-hand 4PROSITE-ProRule annotationAdd BLAST36
Domaini197 – 232EF-hand 5PROSITE-ProRule annotationAdd BLAST36
Domaini240 – 276EF-hand 6PROSITE-ProRule annotationAdd BLAST37

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00390000013118
HOGENOMiHOG000231866
HOVERGENiHBG000855
InParanoidiQ91WD9
OMAiHHKKAIS
OrthoDBiEOG091G0GNH
PhylomeDBiQ91WD9
TreeFamiTF325083

Family and domain databases

CDDicd16178 EFh_HEF_SCGN, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR035798 EFh_SCGN
PfamiView protein in Pfam
PF13202 EF-hand_5, 1 hit
PF13499 EF-hand_7, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 5 hits
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 5 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q91WD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNARRKTPA RLDAACFWQI WQRFDKEEKG YIRETELDAF FDHLLAKSGT
60 70 80 90 100
EDTLMEENVQ KVKEQLMTSH NVSKEGRILM KELASMFLSE DENFLLFFRL
110 120 130 140 150
ETPLDNSVEF MQIWRKYDAD SSGFISAAEL CNFLRDLFLH HKKNISEAEL
160 170 180 190 200
EEYTSTMMKI FDKNKDGRLD LNDLARILAL QENFLLQFKM DASSTEERKR
210 220 230 240 250
DFEKIFAHYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL
260 270
RHCDVNKDGK IQKSELALCL GLKINP
Length:276
Mass (Da):32,146
Last modified:December 1, 2001 - v1
Checksum:iDBC86BF7F1CF9987
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YD29A0A286YD29_MOUSE
Secretagogin
Scgn
119Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016093 mRNA Translation: AAH16093.1
CCDSiCCDS26375.1
RefSeqiNP_663374.1, NM_145399.1
UniGeneiMm.255667

Genome annotation databases

EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337
GeneIDi214189
KEGGimmu:214189
UCSCiuc007pvk.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC016093 mRNA Translation: AAH16093.1
CCDSiCCDS26375.1
RefSeqiNP_663374.1, NM_145399.1
UniGeneiMm.255667

3D structure databases

ProteinModelPortaliQ91WD9
SMRiQ91WD9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021770

PTM databases

iPTMnetiQ91WD9
PhosphoSitePlusiQ91WD9

Proteomic databases

MaxQBiQ91WD9
PaxDbiQ91WD9
PeptideAtlasiQ91WD9
PRIDEiQ91WD9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021770; ENSMUSP00000021770; ENSMUSG00000021337
GeneIDi214189
KEGGimmu:214189
UCSCiuc007pvk.1 mouse

Organism-specific databases

CTDi10590
MGIiMGI:2384873 Scgn

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00390000013118
HOGENOMiHOG000231866
HOVERGENiHBG000855
InParanoidiQ91WD9
OMAiHHKKAIS
OrthoDBiEOG091G0GNH
PhylomeDBiQ91WD9
TreeFamiTF325083

Miscellaneous databases

PROiPR:Q91WD9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021337 Expressed in 82 organ(s), highest expression level in islet of Langerhans
CleanExiMM_SCGN
ExpressionAtlasiQ91WD9 baseline and differential
GenevisibleiQ91WD9 MM

Family and domain databases

CDDicd16178 EFh_HEF_SCGN, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR035798 EFh_SCGN
PfamiView protein in Pfam
PF13202 EF-hand_5, 1 hit
PF13499 EF-hand_7, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 5 hits
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiSEGN_MOUSE
AccessioniPrimary (citable) accession number: Q91WD9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: December 1, 2001
Last modified: October 10, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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