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Protein

RUS1 family protein C16orf58 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
RUS1 family protein C16orf58 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2384572 BC017158

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002829312 – 466RUS1 family protein C16orf58 homologAdd BLAST465

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ91W34
PaxDbiQ91W34
PeptideAtlasiQ91W34
PRIDEiQ91W34

PTM databases

iPTMnetiQ91W34
PhosphoSitePlusiQ91W34
SwissPalmiQ91W34

Expressioni

Gene expression databases

CleanExiMM_BC017158

Interactioni

Protein-protein interaction databases

IntActiQ91W34, 1 interactor
MINTiQ91W34
STRINGi10090.ENSMUSP00000033044

Family & Domainsi

Sequence similaritiesi

Belongs to the RUS1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4249 Eukaryota
ENOG410XU74 LUCA
HOGENOMiHOG000030128
HOVERGENiHBG057219
InParanoidiQ91W34
PhylomeDBiQ91W34
TreeFamiTF326424

Family and domain databases

InterProiView protein in InterPro
IPR006968 RUS_fam
PANTHERiPTHR12770 PTHR12770, 1 hit
PfamiView protein in Pfam
PF04884 DUF647, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q91W34-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADAASLRAP LCTEQFGSGA PRGCSAAADG SLQWDGARRW GWLSRAPIAK
60 70 80 90 100
PGQHAGGGGG PWAALTALSG LRSVLLPQGF PDSVSPDYLP YQLWDSVQAF
110 120 130 140 150
ASSLSGSLAT QAVLQGLGVG NAKASVSAAT STWLVKDSTG MLGRIILAWW
160 170 180 190 200
KGSKLDCNAK QWRLFADILN DVAMFLEIMA PMYPIFFTMT VSTSNLAKCI
210 220 230 240 250
VGVAGGATRA ALTMHQARRN NMADVSAKDS SQETVVNLAG LLVSLLMLPL
260 270 280 290 300
VSDCPSLSLG CFVLLTALHI YANYRAVRAL VLETLNESRL QLVLEHFLQR
310 320 330 340 350
GEVLEPASAN QMEPLWTGFW PSLSLSLGVP LHHLVSSVSE LKQLVEGHHE
360 370 380 390 400
PYLLCWNKSR NQVQVALSQE AGPETVLRAA THGLILGALQ EDGPLPGELA
410 420 430 440 450
ELRHQVQADP KKESWILVRE THQVLDTLFP KFLKGLQAAG WKTEKHHLEV
460
DEWRATWPLS PEKKVL
Length:466
Mass (Da):50,469
Last modified:December 1, 2001 - v1
Checksum:iB546CEDB8F8E4154
GO
Isoform 2 (identifier: Q91W34-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     317-337: TGFWPSLSLSLGVPLHHLVSS → IGDPSLWFLVPGFPSLPSPSA
     338-466: Missing.

Show »
Length:337
Mass (Da):35,788
Checksum:i9125A34DD86F26CF
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6ZSG8F6ZSG8_MOUSE
cDNA sequence BC017158
BC017158
83Annotation score:
D6RDS0D6RDS0_MOUSE
cDNA sequence BC017158
BC017158
347Annotation score:
A0A0R4J0B5A0A0R4J0B5_MOUSE
cDNA sequence BC017158
BC017158 mCG_21019
466Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti41G → C in BAE28428 (PubMed:16141072).Curated1
Sequence conflicti147L → F in BAE41911 (PubMed:16141072).Curated1
Sequence conflicti147L → F in BAE29003 (PubMed:16141072).Curated1
Sequence conflicti147L → F in BAE28428 (PubMed:16141072).Curated1
Sequence conflicti364Q → R in BAE29003 (PubMed:16141072).Curated1
Sequence conflicti364Q → R in BAE28428 (PubMed:16141072).Curated1
Sequence conflicti401E → Q in BAE29003 (PubMed:16141072).Curated1
Sequence conflicti401E → Q in BAE28428 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_024257317 – 337TGFWP…HLVSS → IGDPSLWFLVPGFPSLPSPS A in isoform 2. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_024258338 – 466Missing in isoform 2. 1 PublicationAdd BLAST129

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK148236 mRNA Translation: BAE28428.1
AK149645 mRNA Translation: BAE29003.1
AK170611 mRNA Translation: BAE41911.1
BC017158 mRNA Translation: AAH17158.1
CCDSiCCDS21895.1 [Q91W34-1]
RefSeqiNP_663565.2, NM_145590.2
UniGeneiMm.220880

Genome annotation databases

GeneIDi233913
KEGGimmu:233913
UCSCiuc009jyv.2 mouse [Q91W34-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK148236 mRNA Translation: BAE28428.1
AK149645 mRNA Translation: BAE29003.1
AK170611 mRNA Translation: BAE41911.1
BC017158 mRNA Translation: AAH17158.1
CCDSiCCDS21895.1 [Q91W34-1]
RefSeqiNP_663565.2, NM_145590.2
UniGeneiMm.220880

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ91W34, 1 interactor
MINTiQ91W34
STRINGi10090.ENSMUSP00000033044

PTM databases

iPTMnetiQ91W34
PhosphoSitePlusiQ91W34
SwissPalmiQ91W34

Proteomic databases

EPDiQ91W34
PaxDbiQ91W34
PeptideAtlasiQ91W34
PRIDEiQ91W34

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi233913
KEGGimmu:233913
UCSCiuc009jyv.2 mouse [Q91W34-1]

Organism-specific databases

MGIiMGI:2384572 BC017158

Phylogenomic databases

eggNOGiKOG4249 Eukaryota
ENOG410XU74 LUCA
HOGENOMiHOG000030128
HOVERGENiHBG057219
InParanoidiQ91W34
PhylomeDBiQ91W34
TreeFamiTF326424

Miscellaneous databases

PROiPR:Q91W34

Gene expression databases

CleanExiMM_BC017158

Family and domain databases

InterProiView protein in InterPro
IPR006968 RUS_fam
PANTHERiPTHR12770 PTHR12770, 1 hit
PfamiView protein in Pfam
PF04884 DUF647, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRUS1_MOUSE
AccessioniPrimary (citable) accession number: Q91W34
Secondary accession number(s): Q3TCP4, Q3UEA8, Q3UFY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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