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Protein

Ubiquitin-associated protein 2

Gene

Ubap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-associated protein 2
Short name:
UBAP-2
Alternative name(s):
Protein lingerer homolog 1
Short name:
mLig-1
Gene namesi
Name:Ubap2Imported
Synonyms:Lig1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1916176 Ubap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002709821 – 1132Ubiquitin-associated protein 2Add BLAST1132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei166Omega-N-methylarginineBy similarity1
Modified residuei433PhosphoserineBy similarity1
Modified residuei440PhosphoserineBy similarity1
Modified residuei631PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

EPDiQ91VX2
MaxQBiQ91VX2
PaxDbiQ91VX2
PRIDEiQ91VX2

PTM databases

iPTMnetiQ91VX2
PhosphoSitePlusiQ91VX2

Expressioni

Gene expression databases

BgeeiENSMUSG00000028433 Expressed in 288 organ(s), highest expression level in muscle tissue
CleanExiMM_LIG1
MM_UBAP2
ExpressionAtlasiQ91VX2 baseline and differential
GenevisibleiQ91VX2 MM

Interactioni

Protein-protein interaction databases

BioGridi213121, 2 interactors
IntActiQ91VX2, 3 interactors
MINTiQ91VX2
STRINGi10090.ENSMUSP00000030143

Structurei

3D structure databases

ProteinModelPortaliQ91VX2
SMRiQ91VX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 92UBASequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi543 – 795Ser-richSequence analysisAdd BLAST253

Phylogenomic databases

eggNOGiENOG410IGWX Eukaryota
ENOG4110RI8 LUCA
GeneTreeiENSGT00390000003453
HOGENOMiHOG000231679
HOVERGENiHBG058387
InParanoidiQ91VX2
OrthoDBiEOG091G0GRY
PhylomeDBiQ91VX2
TreeFamiTF328468

Family and domain databases

InterProiView protein in InterPro
IPR022166 DUF3697_Uba2
IPR015940 UBA
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF12478 DUF3697, 1 hit
SMARTiView protein in SMART
SM00165 UBA, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q91VX2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMTSVSNDRC RGAREKPQMP TAHAAQSQKQ VVQATAEQMR LAQVIFDKND
60 70 80 90 100
SDFEAKVKQL MEVTGKNQDE CIVALHDCNG DVNKAINILL EGNSDTTSWE
110 120 130 140 150
TVGGKKKNFG RESSENKENR EKRTEREASR GRGTNNRKGR GGNRVREFKG
160 170 180 190 200
EENGIDCSQG DKPAERGKRA RGRGFGRGRG RGTGRFSAQS MGTFNPADYS
210 220 230 240 250
ESMSTDGCGT KLAVWEAAQN GTDEGPEGLA KSHSMSQEPP SKSSYGLKGA
260 270 280 290 300
WKNSVEEWTT EDWTEDLSET KVFTASSAPA ENHVTPGHSI DLVALLHKPA
310 320 330 340 350
PPTQATEVNS FETSQQQGFG QALVFTNSQH NNQMAPGTAN STSASSYSPQ
360 370 380 390 400
SLSSVLGSGF GELPQSNMVN ISNSQILDKL KPPGLSPFPA ASSAQQNDTA
410 420 430 440 450
SPPATTAAWD LKPSAPQPSV LSRLDFKSQP EPSPVLSQLS QRQQHQTQAV
460 470 480 490 500
SVPPPGLESF SSLAKPREST AGDGPSTVSR LLQLPNMTVE NIVSAHQPQP
510 520 530 540 550
KHIKLPKRRV PPASKVPVSA VEMPGSSDVT GLNVQFGALE FGSEPSLSEF
560 570 580 590 600
GSAASASENS NQIPISLYPK SLSEPLNASF PMTSAVQSST YTTSVVTSST
610 620 630 640 650
LTSSALSSTS PVTTSSSYDQ SSVHTRIAYQ SSASPPDSAP GSVANGHGGG
660 670 680 690 700
RSQHTVDTTS SVPAPKKTDP SALPSVSTLP GPASCTALLP SSAQHTATLP
710 720 730 740 750
SLTPAAAELS SSPLSQLSSS LSGHQNSMTS AHATRSTSTP HTHASVESTA
760 770 780 790 800
SSAAFSAAAT SAPSAPSSGV VLPGSMSTVS SLCLGGTTVS VPSSSTRATA
810 820 830 840 850
LVTSGKAPPN LPQGVPPLLH NQYLVGPGGL LPAYPIYGYD ELQMLQSRLP
860 870 880 890 900
MDYYGIPFAA PTALASRDGN LANNPYSGDV TKFGRGDSAS PAPPTTPAQA
910 920 930 940 950
QQSQSQTHHT AQQPFLNPGL PPGYSYTGLP YYTGVPSAFQ YGPTMFVPPT
960 970 980 990 1000
SAKQHGVALS TPPTPFQQAS GYGQHAYSTG YDDLTQGTAA GDYTKGGYGG
1010 1020 1030 1040 1050
SSQAPNKSTG SGPGKGVSVS SGTGLPDMTG SVYNKTQTFD KQGFHAGTPP
1060 1070 1080 1090 1100
PFSLPSALGS TGPLAPAAAP GYAPAPFLHI MPAHQQPHSQ LLHHHLQQDA
1110 1120 1130
PSGSGQRSQP SSLQPKSQAS KPTYGSAPYW TN
Length:1,132
Mass (Da):117,966
Last modified:December 1, 2001 - v1
Checksum:iECF8E72C9134BB38
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2AMY5A2AMY5_MOUSE
Ubiquitin-associated protein 2
Ubap2
1,131Annotation score:
F6PYV5F6PYV5_MOUSE
Ubiquitin-associated protein 2
Ubap2
245Annotation score:
A2AMY7A2AMY7_MOUSE
Ubiquitin-associated protein 2
Ubap2
227Annotation score:
F6WTC8F6WTC8_MOUSE
Ubiquitin-associated protein 2
Ubap2
140Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti698T → A in AAO23024 (PubMed:12524348).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276965 mRNA Translation: AAO23024.1
BC005482 mRNA Translation: AAH05482.1
BC007179 mRNA Translation: AAH07179.1
CCDSiCCDS18058.1
RefSeqiNP_081148.1, NM_026872.1
XP_006538287.1, XM_006538224.1
UniGeneiMm.41864

Genome annotation databases

EnsembliENSMUST00000030143; ENSMUSP00000030143; ENSMUSG00000028433
GeneIDi68926
KEGGimmu:68926
UCSCiuc008sik.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276965 mRNA Translation: AAO23024.1
BC005482 mRNA Translation: AAH05482.1
BC007179 mRNA Translation: AAH07179.1
CCDSiCCDS18058.1
RefSeqiNP_081148.1, NM_026872.1
XP_006538287.1, XM_006538224.1
UniGeneiMm.41864

3D structure databases

ProteinModelPortaliQ91VX2
SMRiQ91VX2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi213121, 2 interactors
IntActiQ91VX2, 3 interactors
MINTiQ91VX2
STRINGi10090.ENSMUSP00000030143

PTM databases

iPTMnetiQ91VX2
PhosphoSitePlusiQ91VX2

Proteomic databases

EPDiQ91VX2
MaxQBiQ91VX2
PaxDbiQ91VX2
PRIDEiQ91VX2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030143; ENSMUSP00000030143; ENSMUSG00000028433
GeneIDi68926
KEGGimmu:68926
UCSCiuc008sik.1 mouse

Organism-specific databases

CTDi55833
MGIiMGI:1916176 Ubap2

Phylogenomic databases

eggNOGiENOG410IGWX Eukaryota
ENOG4110RI8 LUCA
GeneTreeiENSGT00390000003453
HOGENOMiHOG000231679
HOVERGENiHBG058387
InParanoidiQ91VX2
OrthoDBiEOG091G0GRY
PhylomeDBiQ91VX2
TreeFamiTF328468

Miscellaneous databases

PROiPR:Q91VX2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028433 Expressed in 288 organ(s), highest expression level in muscle tissue
CleanExiMM_LIG1
MM_UBAP2
ExpressionAtlasiQ91VX2 baseline and differential
GenevisibleiQ91VX2 MM

Family and domain databases

InterProiView protein in InterPro
IPR022166 DUF3697_Uba2
IPR015940 UBA
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF12478 DUF3697, 1 hit
SMARTiView protein in SMART
SM00165 UBA, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUBAP2_MOUSE
AccessioniPrimary (citable) accession number: Q91VX2
Secondary accession number(s): Q812D6, Q99K40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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