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Entry version 144 (02 Jun 2021)
Sequence version 2 (03 Jul 2003)
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Protein

Golgin subfamily A member 4

Gene

Golga4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6811440, Retrograde transport at the Trans-Golgi-Network

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Golgin subfamily A member 4
Alternative name(s):
tGolgin-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Golga4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1859646, Golga4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001900601 – 2238Golgin subfamily A member 4Add BLAST2238

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei10PhosphoserineBy similarity1
Modified residuei39PhosphothreonineCombined sources1
Modified residuei41PhosphoserineBy similarity1
Modified residuei93PhosphoserineBy similarity1
Modified residuei100PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q91VW5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q91VW5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q91VW5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q91VW5

PeptideAtlas

More...
PeptideAtlasi
Q91VW5

PRoteomics IDEntifications database

More...
PRIDEi
Q91VW5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
271028

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q91VW5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q91VW5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous. Highly expressed in oligodendrocyte precursors, particularly at a stage just prior to myelination.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000038708, Expressed in soleus muscle and 332 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q91VW5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q91VW5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts with GTP-bound ARL1 and ARL3 (By similarity).

Interacts with MACF1 (By similarity). Directly interacts with TBC1D23 (PubMed:29084197).

Interacts with FAM91A1; this interaction may be mediated by TBC1D23 (By similarity).

By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
207604, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q91VW5, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000081880

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q91VW5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91VW5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2178 – 2225GRIPPROSITE-ProRule annotationAdd BLAST48

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 90DisorderedSequence analysisAdd BLAST90
Regioni132 – 154DisorderedSequence analysisAdd BLAST23
Regioni154 – 224Interaction with MACF1By similarityAdd BLAST71
Regioni1695 – 1744DisorderedSequence analysisAdd BLAST50
Regioni1770 – 1789DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili156 – 2161Sequence analysisAdd BLAST2006

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 89Polar residuesSequence analysisAdd BLAST79
Compositional biasi1695 – 1714Basic and acidic residuesSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Extended rod-like protein with coiled-coil domains.

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTM0, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111139

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001994_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q91VW5

Database of Orthologous Groups

More...
OrthoDBi
663248at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q91VW5

TreeFam database of animal gene trees

More...
TreeFami
TF325082

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000237, GRIP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01465, GRIP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00755, Grip, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50913, GRIP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q91VW5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFKKLKQKIS EEQQQLQQAL APAQASSSSS TPTRTRSRTS SFTDQLDDVT
60 70 80 90 100
PNRENASTQA TKSPDGVSKD ESSPSQSGDT QTFAQKLQLR VPSMESLFRS
110 120 130 140 150
PIKESLFRSS KEPLVRTSSR ESLNQLDLDC SAAAFDPPSD MESEAEDAPW
160 170 180 190 200
NSDGLSREQL LQRLRRMERS LSSYRGKYSE LVTAFQTLQR EKKKLQGILS
210 220 230 240 250
QSQDKSLRRI SELREELQMD QQAKKHLQDE FDACLEEKDQ YISVLQTQVS
260 270 280 290 300
LLKQRLQNGP MNVDAPKPLP PGELQAEVHG DTEKMEGVGE PVGGGTSAKT
310 320 330 340 350
LEMLQQRVKR QENLLQRCKE TIGSHKEQCA LLLSEKEALQ EQLDERLQEL
360 370 380 390 400
EKMKELHMAE KTKLITQLRD AKNLIEQLEQ DKGMVITETK RQMLETLELK
410 420 430 440 450
EDEIAQLRSH IKQMTTQGEE LREQKEKSER AAFEELEKAL STAQKTEDAQ
460 470 480 490 500
RRMKMEMDEQ MKAVERASEE ERLRLQHELS RVRQEAASMA KKNSEEQVAA
510 520 530 540 550
LQKLHAEELA SKEQELSRRL EARERELQEQ MRIALEKSRS EYLKLTQEKE
560 570 580 590 600
QQESLALEEL ELQKKAILTE SENKLQELGQ EAEAYRTRIL ELETSLEKSL
610 620 630 640 650
QESKTQSEHL AVHLEAEKNK HNKELTALAE QHRTEVEGLQ QQQDSLWTER
660 670 680 690 700
LQSLSQQHQA AVEELREKYQ QEKDALLKEK ESLFQAHIQD MNEKTLEKLD
710 720 730 740 750
KKQMELESVS SELSEALRAR DQLAEELSVL RGDADKMKQA LEAELEEQRR
760 770 780 790 800
HHQREVGSIS EQQELTVRRA EKALKDELSR LGALLDERDE HLRERQARVQ
810 820 830 840 850
DLEAHLQKSA GELQQALAKL DLLHSEQSAA REQAGAYEEQ LAQMQQKVLD
860 870 880 890 900
LETEKSLLTK QVVEMETHKK HVCEELDAQR AQVQQLERQR SELEEKVRSL
910 920 930 940 950
AQLQDSQLKN STVEKEQARQ SLMEKENIIL QMREEQAKEI EILKQTLSSK
960 970 980 990 1000
EESISILHEE YETKFKNQEK RMEKIKQKAK EMQETKKKLL DQEAKLKKEL
1010 1020 1030 1040 1050
ENTVLELSQK EKQFNAQILE MAQANSAGIS DTVSRLEENQ RQQIESLTGA
1060 1070 1080 1090 1100
HQRKLDDVIE AWEKKLSQQA AELRDKHAEQ MEEKEQGLGE LRQKVRIVQS
1110 1120 1130 1140 1150
EKEELTKEVA RLKEAVSGQD VALAGLQGQL EQKSAVIVSL SERESQLQSQ
1160 1170 1180 1190 1200
VEKLEADLGC SLSEKLSLQE ELAELKLLAD KSQLRVSELT GQVQAAEKEL
1210 1220 1230 1240 1250
QSCKSLHELS KKSLEDKSLN LKSLLEELAS QLDSRCERTK ALLEAKTNEL
1260 1270 1280 1290 1300
VCTSRDKADA ILARLSQCQR HTATVGEALL RRMGQVSELE AQLTQLTEEQ
1310 1320 1330 1340 1350
RTLKSSFQQV TNQLEEKEKQ IKTMKADIEG LLTEKEALQQ EGGQQRQAAS
1360 1370 1380 1390 1400
EKESCITQLK KELAENINAV TLLREELSEK KSEIASLSKQ LSDLGAQLES
1410 1420 1430 1440 1450
SISPSDKAEA ISALSKQHEE QELQLQAQLQ ELSLKVDALS KEKMSALEQV
1460 1470 1480 1490 1500
DHWSNKFSEW KKKAQSRLAQ HQSTIKDLQA QLDVKATDAR EKEEQICLLK
1510 1520 1530 1540 1550
EDLDRQNKKF ECLKGEMEVR KSKMEKKECD LETALKTQTA RVVELEDCVT
1560 1570 1580 1590 1600
QRKKEVESLN ETLKNYNQQR DTEHSGLVQR LQHLEELGEE KDNKVREAEE
1610 1620 1630 1640 1650
TVLRLREHVS SLEAELGTVK KELEHVNSSV KSRDGELKAL EDKLELESAA
1660 1670 1680 1690 1700
KVELKRKAEQ KIAAIRKQLL SQMEEKTQRY AKDTENRLSE LSAQLKEREK
1710 1720 1730 1740 1750
QVHSLEDKLK NLESSPHPEV PAVSRSMQSV AASPEQEAPD SQDCTHKACK
1760 1770 1780 1790 1800
ERLCMLQRRL SEKEKLLRRL EQGEGEARPS QPEAQHRALS GKLDCTRARQ
1810 1820 1830 1840 1850
LEDHVLIGCL PEELEEKMKC SLIVSQPMGE ETGNNTGVKQ NWASVVDSVQ
1860 1870 1880 1890 1900
KTLQEKELTC QALEQRVKEL ESDLVRERGA HRLEVEKLTL KYEKSQSSQQ
1910 1920 1930 1940 1950
EMDGENKCVE VLEDRPEENS QSHEIQSNVG TVDGLRSDLE SKLTGAERDK
1960 1970 1980 1990 2000
QKLSKEVARL QKELRALRRE HQQELDILKR ECEQEAEEKL KQEQEDLELK
2010 2020 2030 2040 2050
HTSTLKQLMR EFNTQLAQKE QELERTVQET IDKAQEVEAE LLESHQEETQ
2060 2070 2080 2090 2100
QLHRKIAEKE DDLRRTARRY EEILDAREEE MTGKVTDLQT QLEELQKKYQ
2110 2120 2130 2140 2150
QRLEQEESTK DSVTILELQT QLAQKTTLIS DSKLKEQELR EQVHNLEDRL
2160 2170 2180 2190 2200
KRYEKNACAA TVGTPYKGGN LYHTEVSLFG EPTEFEYLRK VMFEYMMGRE
2210 2220 2230
TKTMAKVITT VLKFPDDQAQ KILEREDARL MSWLRTSS
Length:2,238
Mass (Da):257,564
Last modified:July 3, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i494EA2C111F0165B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5RLV4A0A1D5RLV4_MOUSE
Golgin subfamily A member 4
Golga4
1,251Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RLC6A0A1D5RLC6_MOUSE
Golgin subfamily A member 4
Golga4
454Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RME8A0A1D5RME8_MOUSE
Golgin subfamily A member 4
Golga4
941Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RM19A0A1D5RM19_MOUSE
Golgin subfamily A member 4
Golga4
111Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RL95A0A1D5RL95_MOUSE
Golgin subfamily A member 4
Golga4
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RLH4A0A1D5RLH4_MOUSE
Golgin subfamily A member 4
Golga4
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH37641 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti61T → R in strain: Czech II. 1 Publication1
Natural varianti280G → S in strain: Czech II. 1 Publication1
Natural varianti293G → E in strain: Czech II. 1 Publication1
Natural varianti638G → S in strain: Czech II. 1 Publication1
Natural varianti819K → T in strain: Czech II. 1 Publication1
Natural varianti829A → T in strain: Czech II. 1 Publication1
Natural varianti859T → A in strain: Czech II. 1 Publication1
Natural varianti2065R → S in strain: C57BL/6. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF051357 mRNA Translation: AAC05573.2
BC007485 mRNA Translation: AAH07485.1
BC037641 mRNA Translation: AAH37641.1 Different initiation.
BC053000 mRNA Translation: AAH53000.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40801.1

Protein sequence database of the Protein Information Resource

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PIRi
T14265

NCBI Reference Sequences

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RefSeqi
NP_061218.2, NM_018748.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000084820; ENSMUSP00000081880; ENSMUSG00000038708

Database of genes from NCBI RefSeq genomes

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GeneIDi
54214

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:54214

UCSC genome browser

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UCSCi
uc009rzs.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051357 mRNA Translation: AAC05573.2
BC007485 mRNA Translation: AAH07485.1
BC037641 mRNA Translation: AAH37641.1 Different initiation.
BC053000 mRNA Translation: AAH53000.1
CCDSiCCDS40801.1
PIRiT14265
RefSeqiNP_061218.2, NM_018748.3

3D structure databases

SMRiQ91VW5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi207604, 8 interactors
IntActiQ91VW5, 3 interactors
STRINGi10090.ENSMUSP00000081880

PTM databases

iPTMnetiQ91VW5
PhosphoSitePlusiQ91VW5

Proteomic databases

EPDiQ91VW5
jPOSTiQ91VW5
MaxQBiQ91VW5
PaxDbiQ91VW5
PeptideAtlasiQ91VW5
PRIDEiQ91VW5
ProteomicsDBi271028

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
28305, 90 antibodies

The DNASU plasmid repository

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DNASUi
54214

Genome annotation databases

EnsembliENSMUST00000084820; ENSMUSP00000081880; ENSMUSG00000038708
GeneIDi54214
KEGGimmu:54214
UCSCiuc009rzs.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
2803
MGIiMGI:1859646, Golga4

Phylogenomic databases

eggNOGiENOG502QTM0, Eukaryota
GeneTreeiENSGT00730000111139
HOGENOMiCLU_001994_0_0_1
InParanoidiQ91VW5
OrthoDBi663248at2759
PhylomeDBiQ91VW5
TreeFamiTF325082

Enzyme and pathway databases

ReactomeiR-MMU-6811440, Retrograde transport at the Trans-Golgi-Network

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
54214, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Golga4, mouse

Protein Ontology

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PROi
PR:Q91VW5
RNActiQ91VW5, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000038708, Expressed in soleus muscle and 332 other tissues
ExpressionAtlasiQ91VW5, baseline and differential
GenevisibleiQ91VW5, MM

Family and domain databases

InterProiView protein in InterPro
IPR000237, GRIP_dom
PfamiView protein in Pfam
PF01465, GRIP, 1 hit
SMARTiView protein in SMART
SM00755, Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913, GRIP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGOGA4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91VW5
Secondary accession number(s): O70365, Q8CGH6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: July 3, 2003
Last modified: June 2, 2021
This is version 144 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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