UniProtKB - Q91VR2 (ATPG_MOUSE)
ATP synthase subunit gamma, mitochondrial
Atp5f1c
Functioni
GO - Molecular functioni
- proton-transporting ATP synthase activity, rotational mechanism Source: Ensembl
GO - Biological processi
- ATP biosynthetic process Source: GO_Central
- ATP metabolic process Source: MGI
- ATP synthesis coupled proton transport Source: GO_Central
- mitochondrial ATP synthesis coupled proton transport Source: MGI
Keywordsi
Biological process | ATP synthesis, Hydrogen ion transport, Ion transport, Transport |
Enzyme and pathway databases
Reactomei | R-MMU-163210, Formation of ATP by chemiosmotic coupling R-MMU-8949613, Cristae formation |
Names & Taxonomyi
Protein namesi | Recommended name: ATP synthase subunit gamma, mitochondrialCuratedAlternative name(s): ATP synthase F1 subunit gammaBy similarity F-ATPase gamma subunit |
Gene namesi | Name:Atp5f1cBy similarity Synonyms:Atp5c1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1261437, Atp5c1 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Peripheral membrane protein By similarity; Matrix side By similarity
Mitochondrion
- mitochondrial inner membrane Source: MGI
- mitochondrial proton-transporting ATP synthase complex Source: UniProtKB
- mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) Source: MGI
- mitochondrion Source: MGI
Other locations
- myelin sheath Source: UniProtKB
- proton-transporting ATP synthase complex, catalytic core F(1) Source: MGI
Keywords - Cellular componenti
CF(1), Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 25 | MitochondrionAdd BLAST | 25 | |
ChainiPRO_0000002686 | 26 – 298 | ATP synthase subunit gamma, mitochondrialAdd BLAST | 273 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 39 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 49 | N6-succinyllysineCombined sources | 1 | |
Modified residuei | 55 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 115 | N6-acetyllysine; alternateCombined sources | 1 | |
Modified residuei | 115 | N6-succinyllysine; alternateCombined sources | 1 | |
Modified residuei | 138 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 146 | PhosphoserineCombined sources | 1 | |
Modified residuei | 154 | N6-acetyllysine; alternateCombined sources | 1 | |
Modified residuei | 154 | N6-succinyllysine; alternateCombined sources | 1 | |
Modified residuei | 197 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 270 | N6-succinyllysineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q91VR2 |
jPOSTi | Q91VR2 |
MaxQBi | Q91VR2 |
PaxDbi | Q91VR2 |
PRIDEi | Q91VR2 |
2D gel databases
UCD-2DPAGEi | Q91VR2 |
PTM databases
iPTMneti | Q91VR2 |
PhosphoSitePlusi | Q91VR2 |
SwissPalmi | Q91VR2 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000025781, Expressed in extra-ocular muscle and 152 other tissues |
ExpressionAtlasi | Q91VR2, baseline and differential |
Genevisiblei | Q91VR2, MM |
Interactioni
Subunit structurei
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MD and ATP5MPL (By similarity).
By similarityProtein-protein interaction databases
BioGRIDi | 198255, 74 interactors |
IntActi | Q91VR2, 16 interactors |
MINTi | Q91VR2 |
STRINGi | 10090.ENSMUSP00000110547 |
Miscellaneous databases
RNActi | Q91VR2, protein |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG1531, Eukaryota |
GeneTreei | ENSGT00390000006837 |
InParanoidi | Q91VR2 |
OrthoDBi | 841252at2759 |
PhylomeDBi | Q91VR2 |
TreeFami | TF105765 |
Family and domain databases
CDDi | cd12151, F1-ATPase_gamma, 1 hit |
InterProi | View protein in InterPro IPR035968, ATP_synth_F1_ATPase_gsu IPR000131, ATP_synth_F1_gsu IPR023632, ATP_synth_F1_gsu_CS |
PANTHERi | PTHR11693, PTHR11693, 1 hit |
Pfami | View protein in Pfam PF00231, ATP-synt, 1 hit |
PRINTSi | PR00126, ATPASEGAMMA |
SUPFAMi | SSF52943, SSF52943, 1 hit |
TIGRFAMsi | TIGR01146, ATPsyn_F1gamma, 1 hit |
PROSITEi | View protein in PROSITE PS00153, ATPASE_GAMMA, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MFSRASVVGL SACAVQPQWI QVRNMATLKD ITRRLKSIKN IQKITKSMKM
60 70 80 90 100
VAAAKYARAE RELKPARVYG TGSLALYEKA DIKAPEDKKK HLIIGVSSDR
110 120 130 140 150
GLCGAIHSSV AKQMKNEVAA LTAAGKEVMI VGVGEKIKGI LYRTHSDQFL
160 170 180 190 200
VSFKDVGRKP PTFGDASVIA LELLNSGYEF DEGSIIFNQF KSVISYKTEE
210 220 230 240 250
KPIFSLNTIA TAETMSIYDD IDADVLQNYQ EYNLANLIYY SLKESTTSEQ
260 270 280 290
SARMTAMDNA SKNASDMIDK LTLTFNRTRQ AVITKELIEI ISGAAALD
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA2AKU9 | A2AKU9_MOUSE | ATP synthase subunit gamma | Atp5c1 | 297 | Annotation score: | ||
Q8C2Q8 | Q8C2Q8_MOUSE | ATP synthase subunit gamma | Atp5c1 | 274 | Annotation score: | ||
A2AKV1 | A2AKV1_MOUSE | ATP synthase, H+-transporting, mito... | Atp5c1 | 154 | Annotation score: | ||
A2AKV2 | A2AKV2_MOUSE | ATP synthase, H+-transporting, mito... | Atp5c1 | 171 | Annotation score: | ||
A2AKV3 | A2AKV3_MOUSE | ATP synthase, H+-transporting, mito... | Atp5c1 | 188 | Annotation score: | ||
A2AKV0 | A2AKV0_MOUSE | ATP synthase, H+-transporting, mito... | Atp5c1 | 101 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC010700 mRNA Translation: AAH10700.1 |
CCDSi | CCDS38045.1 |
RefSeqi | NP_065640.2, NM_020615.4 |
Genome annotation databases
Ensembli | ENSMUST00000114897; ENSMUSP00000110547; ENSMUSG00000025781 |
GeneIDi | 11949 |
KEGGi | mmu:11949 |
UCSCi | uc008ihm.3, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC010700 mRNA Translation: AAH10700.1 |
CCDSi | CCDS38045.1 |
RefSeqi | NP_065640.2, NM_020615.4 |
3D structure databases
SMRi | Q91VR2 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 198255, 74 interactors |
IntActi | Q91VR2, 16 interactors |
MINTi | Q91VR2 |
STRINGi | 10090.ENSMUSP00000110547 |
PTM databases
iPTMneti | Q91VR2 |
PhosphoSitePlusi | Q91VR2 |
SwissPalmi | Q91VR2 |
2D gel databases
UCD-2DPAGEi | Q91VR2 |
Proteomic databases
EPDi | Q91VR2 |
jPOSTi | Q91VR2 |
MaxQBi | Q91VR2 |
PaxDbi | Q91VR2 |
PRIDEi | Q91VR2 |
Protocols and materials databases
Antibodypediai | 54768, 250 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000114897; ENSMUSP00000110547; ENSMUSG00000025781 |
GeneIDi | 11949 |
KEGGi | mmu:11949 |
UCSCi | uc008ihm.3, mouse |
Organism-specific databases
CTDi | 11949 |
MGIi | MGI:1261437, Atp5c1 |
Phylogenomic databases
eggNOGi | KOG1531, Eukaryota |
GeneTreei | ENSGT00390000006837 |
InParanoidi | Q91VR2 |
OrthoDBi | 841252at2759 |
PhylomeDBi | Q91VR2 |
TreeFami | TF105765 |
Enzyme and pathway databases
Reactomei | R-MMU-163210, Formation of ATP by chemiosmotic coupling R-MMU-8949613, Cristae formation |
Miscellaneous databases
BioGRID-ORCSi | 11949, 10 hits in 18 CRISPR screens |
ChiTaRSi | Atp5c1, mouse |
PROi | PR:Q91VR2 |
RNActi | Q91VR2, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000025781, Expressed in extra-ocular muscle and 152 other tissues |
ExpressionAtlasi | Q91VR2, baseline and differential |
Genevisiblei | Q91VR2, MM |
Family and domain databases
CDDi | cd12151, F1-ATPase_gamma, 1 hit |
InterProi | View protein in InterPro IPR035968, ATP_synth_F1_ATPase_gsu IPR000131, ATP_synth_F1_gsu IPR023632, ATP_synth_F1_gsu_CS |
PANTHERi | PTHR11693, PTHR11693, 1 hit |
Pfami | View protein in Pfam PF00231, ATP-synt, 1 hit |
PRINTSi | PR00126, ATPASEGAMMA |
SUPFAMi | SSF52943, SSF52943, 1 hit |
TIGRFAMsi | TIGR01146, ATPsyn_F1gamma, 1 hit |
PROSITEi | View protein in PROSITE PS00153, ATPASE_GAMMA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ATPG_MOUSE | |
Accessioni | Q91VR2Primary (citable) accession number: Q91VR2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 27, 2002 |
Last sequence update: | December 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 164 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families