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Protein
Submitted name:

Protocadherin beta 10

Gene

Pcdhb10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell adhesion Source: GO_Central
  • homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin beta 10Imported
Submitted name:
Protocadherin-betaJImported
Gene namesi
Name:Pcdhb10Imported
Synonyms:Pcdhb5dImported
ORF Names:mCG_141287Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136745 Pcdhb10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei687 – 710HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501509949031 – 797Sequence analysisAdd BLAST767

Expressioni

Gene expression databases

BgeeiENSMUSG00000045657 Expressed in 42 organ(s), highest expression level in humerus

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056420

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 240CAInterPro annotationAdd BLAST86
Domaini264 – 344CAInterPro annotationAdd BLAST81
Domaini367 – 448CAInterPro annotationAdd BLAST82
Domaini472 – 558CAInterPro annotationAdd BLAST87
Domaini588 – 669CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOGENOMiHOG000220892
HOVERGENiHBG054878
KOiK16494
OMAiCRATEPC
OrthoDBiEOG091G024L
TreeFamiTF332299

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR030730 PCDHB5
PANTHERiPTHR24028:SF90 PTHR24028:SF90, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits

Sequencei

Sequence statusi: Complete.

Q91VE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEMTLAKTPE NRQVLFFTIL LLLWKSCADA IIYSIPEETE SGYLVANLAK
60 70 80 90 100
DLGLRVGELA IRGARIHYKG NKELLQLDAE TGNLFLKEKP DREVLCRATE
110 120 130 140 150
PCVLHFQIIL ENPVQFFQTE LQLTDINDHS PEFPDRKMLL KIPESAQPGT
160 170 180 190 200
TFPLKAAQDP DIGSNAVQNY TVSPNLHFHV VTLSRSDGRK YPELVLDRAL
210 220 230 240 250
DREEQPELTL ILTALDGGAP PRSGTTEVHI EVVDINDNAP QFIQSLYEVQ
260 270 280 290 300
ILENSPLDAL VATVSARDLD AGIYGKVAYS LFQDDGISQP FVIDEITGEI
310 320 330 340 350
RLKGALDFEA TPYYNMEIVA TDPGGFSGKC TVVIQVVDVN DNAPKLTISS
360 370 380 390 400
LNSSIPENAP ETVVAVFSVS DPDSGENGRM VCSIQNELPF LLKSTFENYY
410 420 430 440 450
TLVTEGTLDR ESKAEYNITI SVTDLGTPRL TTQHTITVQV SDINDNAPTF
460 470 480 490 500
TRTSYTMFIR ENNSPALHIG TISATDSDAG SNAHITYSLL PPHDPQLTLT
510 520 530 540 550
SLVSINEDNG QLFALRALDY EALRAFEFHV RATDRGSPAL SSQALVLVVV
560 570 580 590 600
LDDNDNEPFV LYPLQNSSAP CKELVPRAAE AGYLVTKVVA VDRDSGQNAW
610 620 630 640 650
LSFQLLKATE PGLFSVWAHN GEVRTTRLLS ERDAPKHRLL LVVKDNGDPP
660 670 680 690 700
RSASVTLHVL LVDGFSQPYL PLSEVVQDPA QEGDDALTLY LVIALASVSS
710 720 730 740 750
LFLISVLLFV GMKLCKRARS PSLGVCSVPE GHFPGHLVDV SGTGTLSQSY
760 770 780 790
QYEVCLSGDS GTGEFKFLKP MISNLMVQDP EREVKESPHC RDSFVFS
Length:797
Mass (Da):87,530
Last modified:December 1, 2001 - v1
Checksum:i09DED8BD198AF86F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020974 Genomic DNA No translation available.
AY013771 mRNA Translation: AAK26060.1
AF326303 Genomic DNA Translation: AAK53228.1
CH466528 Genomic DNA Translation: EDL10161.1
RefSeqiNP_444365.1, NM_053135.2
UniGeneiMm.115996

Genome annotation databases

EnsembliENSMUST00000051126; ENSMUSP00000056420; ENSMUSG00000045657
GeneIDi93881
KEGGimmu:93881
UCSCiuc008epv.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020974 Genomic DNA No translation available.
AY013771 mRNA Translation: AAK26060.1
AF326303 Genomic DNA Translation: AAK53228.1
CH466528 Genomic DNA Translation: EDL10161.1
RefSeqiNP_444365.1, NM_053135.2
UniGeneiMm.115996

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056420

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000051126; ENSMUSP00000056420; ENSMUSG00000045657
GeneIDi93881
KEGGimmu:93881
UCSCiuc008epv.1 mouse

Organism-specific databases

CTDi56126
MGIiMGI:2136745 Pcdhb10

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00920000148964
HOGENOMiHOG000220892
HOVERGENiHBG054878
KOiK16494
OMAiCRATEPC
OrthoDBiEOG091G024L
TreeFamiTF332299

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045657 Expressed in 42 organ(s), highest expression level in humerus

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR030730 PCDHB5
PANTHERiPTHR24028:SF90 PTHR24028:SF90, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ91VE5_MOUSE
AccessioniPrimary (citable) accession number: Q91VE5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 7, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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