UniProtKB - Q91V64 (ISOC1_MOUSE)
Protein
Isochorismatase domain-containing protein 1
Gene
Isoc1
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Isochorismatase domain-containing protein 1 |
Gene namesi | Name:Isoc1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1913557, Isoc1 |
Subcellular locationi
Peroxisome
- peroxisome Source: HGNC-UCL
Other locations
- cytoplasm Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000268665 | 1 – 297 | Isochorismatase domain-containing protein 1Add BLAST | 297 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 159 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 278 | N6-succinyllysineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q91V64 |
jPOSTi | Q91V64 |
MaxQBi | Q91V64 |
PaxDbi | Q91V64 |
PeptideAtlasi | Q91V64 |
PRIDEi | Q91V64 |
ProteomicsDBi | 269408 |
PTM databases
iPTMneti | Q91V64 |
PhosphoSitePlusi | Q91V64 |
SwissPalmi | Q91V64 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000024601, Expressed in facial nucleus and 305 other tissues |
ExpressionAtlasi | Q91V64, baseline and differential |
Genevisiblei | Q91V64, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 211371, 12 interactors |
IntActi | Q91V64, 1 interactor |
MINTi | Q91V64 |
STRINGi | 10090.ENSMUSP00000025503 |
Miscellaneous databases
RNActi | Q91V64, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the isochorismatase family.Curated
Phylogenomic databases
eggNOGi | KOG4044, Eukaryota |
GeneTreei | ENSGT00390000006753 |
HOGENOMi | CLU_047255_0_0_1 |
InParanoidi | Q91V64 |
OMAi | FSEEWGQ |
OrthoDBi | 1100720at2759 |
PhylomeDBi | Q91V64 |
TreeFami | TF313459 |
Family and domain databases
Gene3Di | 3.40.50.850, 1 hit |
InterProi | View protein in InterPro IPR000868, Isochorismatase-like IPR036380, Isochorismatase-like_sf |
Pfami | View protein in Pfam PF00857, Isochorismatase, 1 hit |
SUPFAMi | SSF52499, SSF52499, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q91V64-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAAEPSVAA LAGGGVGAGA PSGGVPVLFC FSVFARPASV PHGAGYDVLI
60 70 80 90 100
QKFLSLYGDQ LDMHRKFVVQ LFAEEWGQYV DLPKGFAVSE RCKLRLVPLQ
110 120 130 140 150
IQLTTLGNLT PPSTVFFCCD MQERFRPAIK YFGDIISVGQ RLLQGARILG
160 170 180 190 200
IPVIITEQYP KGLGSTVQEI DLTGVKLVLP KTKFSMVLPE VEAALAEIPG
210 220 230 240 250
VRSVVLFGVE THVCIQQTAL ELVGRGIEVH IVADATSSRS MMDRMFALER
260 270 280 290
LARTGIIVTT SEAVLLQLVA DKDHPKFKEI QNLIKASAPE SGLLSKV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A494B952 | A0A494B952_MOUSE | Isochorismatase domain-containing p... | Isoc1 | 257 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 149 | L → F in BAE31476 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 149 | L → F in BAE31848 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY035213 mRNA Translation: AAK64607.1 AK134794 mRNA Translation: BAE22288.1 AK152763 mRNA Translation: BAE31476.1 AK153257 mRNA Translation: BAE31848.1 BC016576 mRNA Translation: AAH16576.1 |
CCDSi | CCDS29265.1 |
RefSeqi | NP_079754.2, NM_025478.3 |
Genome annotation databases
Ensembli | ENSMUST00000025503; ENSMUSP00000025503; ENSMUSG00000024601 |
GeneIDi | 66307 |
KEGGi | mmu:66307 |
UCSCi | uc008ezq.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY035213 mRNA Translation: AAK64607.1 AK134794 mRNA Translation: BAE22288.1 AK152763 mRNA Translation: BAE31476.1 AK153257 mRNA Translation: BAE31848.1 BC016576 mRNA Translation: AAH16576.1 |
CCDSi | CCDS29265.1 |
RefSeqi | NP_079754.2, NM_025478.3 |
3D structure databases
SMRi | Q91V64 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 211371, 12 interactors |
IntActi | Q91V64, 1 interactor |
MINTi | Q91V64 |
STRINGi | 10090.ENSMUSP00000025503 |
PTM databases
iPTMneti | Q91V64 |
PhosphoSitePlusi | Q91V64 |
SwissPalmi | Q91V64 |
Proteomic databases
EPDi | Q91V64 |
jPOSTi | Q91V64 |
MaxQBi | Q91V64 |
PaxDbi | Q91V64 |
PeptideAtlasi | Q91V64 |
PRIDEi | Q91V64 |
ProteomicsDBi | 269408 |
Protocols and materials databases
Antibodypediai | 63783, 57 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000025503; ENSMUSP00000025503; ENSMUSG00000024601 |
GeneIDi | 66307 |
KEGGi | mmu:66307 |
UCSCi | uc008ezq.1, mouse |
Organism-specific databases
CTDi | 51015 |
MGIi | MGI:1913557, Isoc1 |
Phylogenomic databases
eggNOGi | KOG4044, Eukaryota |
GeneTreei | ENSGT00390000006753 |
HOGENOMi | CLU_047255_0_0_1 |
InParanoidi | Q91V64 |
OMAi | FSEEWGQ |
OrthoDBi | 1100720at2759 |
PhylomeDBi | Q91V64 |
TreeFami | TF313459 |
Miscellaneous databases
BioGRID-ORCSi | 66307, 2 hits in 53 CRISPR screens |
ChiTaRSi | Isoc1, mouse |
PROi | PR:Q91V64 |
RNActi | Q91V64, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000024601, Expressed in facial nucleus and 305 other tissues |
ExpressionAtlasi | Q91V64, baseline and differential |
Genevisiblei | Q91V64, MM |
Family and domain databases
Gene3Di | 3.40.50.850, 1 hit |
InterProi | View protein in InterPro IPR000868, Isochorismatase-like IPR036380, Isochorismatase-like_sf |
Pfami | View protein in Pfam PF00857, Isochorismatase, 1 hit |
SUPFAMi | SSF52499, SSF52499, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ISOC1_MOUSE | |
Accessioni | Q91V64Primary (citable) accession number: Q91V64 Secondary accession number(s): Q3U677 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 12, 2006 |
Last sequence update: | December 1, 2001 | |
Last modified: | April 7, 2021 | |
This is version 127 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families