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Entry version 91 (29 Sep 2021)
Sequence version 1 (01 Dec 2001)
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Protein

Genome polyprotein

Gene

ORF1

Organism
Maize rayado fino virus (isolate Costa Rica/Guapiles) (MRFV)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA replication protein replicates the viral genomic RNA. The central part of this protein possibly functions as an ATP-binding helicase and/or methyltransferase (Probable).

1 Publication

Capsid protein CP1 and CP2 assemble to form an icosahedral capsid, about 30 nm in diameter, and consisting of capsid proteins CP1 and CP2 in a 1:3 ratio. The capsid encapsulates the single-stranded RNA genome. While CP1 is produced as a C-terminal fusion of the replication protein, CP2 may be expressed from a 3'-co-terminal subgenomic RNA.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei722For protease activityPROSITE-ProRule annotation1
Active sitei805For protease activityPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Methyltransferase, Multifunctional enzyme, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Thiol protease, Transferase
Biological processViral RNA replication
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 2 chains:
Capsid protein CP1
Short name:
CP1
Alternative name(s):
Coat protein
Including the following 3 domains:
RNA-directed RNA polymerase (EC:2.7.7.48)
Helicase (EC:3.6.4.13)
Methyltransferase (EC:2.1.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ORF1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMaize rayado fino virus (isolate Costa Rica/Guapiles) (MRFV)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri652669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaOrthornaviraeKitrinoviricotaAlsuviricetesTymoviralesTymoviridaeMarafivirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiZea mays (Maize) [TaxID: 4577]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000400 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Capsid protein, Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004024961 – 2027Genome polyproteinAdd BLAST2027
ChainiPRO_00004024971 – 1799RNA replication proteinAdd BLAST1799
ChainiPRO_00004024981800 – 2027Capsid protein CP1Add BLAST228

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q91TW9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini65 – 226Alphavirus-like MTPROSITE-ProRule annotationAdd BLAST162
Domaini668 – 823Peptidase C21PROSITE-ProRule annotationAdd BLAST156
Domaini881 – 1038(+)RNA virus helicase ATP-bindingAdd BLAST158
Domaini1039 – 1171(+)RNA virus helicase C-terminalAdd BLAST133
Domaini1507 – 1613RdRp catalyticPROSITE-ProRule annotationAdd BLAST107

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni542 – 627DisorderedSequence analysisAdd BLAST86
Regioni659 – 681DisorderedSequence analysisAdd BLAST23
Regioni1823 – 1853DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi547 – 601Pro residuesSequence analysisAdd BLAST55

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.20, 1 hit
3.40.50.300, 1 hit
3.90.70.100, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027351, (+)RNA_virus_helicase_core_dom
IPR002588, Alphavirus-like_MT_dom
IPR043502, DNA/RNA_pol_sf
IPR027417, P-loop_NTPase
IPR008043, Peptidase_C21
IPR007094, RNA-dir_pol_PSvirus
IPR043629, Salyut_dom
IPR000574, Tymo_coat
IPR001788, Tymovirus_RNA-dep_RNA_pol
IPR043181, TYMV_endopept_dom
IPR029053, Viral_coat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05381, Peptidase_C21, 1 hit
PF00978, RdRP_2, 1 hit
PF19227, Salyut, 1 hit
PF00983, Tymo_coat, 1 hit
PF01443, Viral_helicase1, 1 hit
PF01660, Vmethyltransf, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51743, ALPHAVIRUS_MT, 1 hit
PS51738, PEPTIDASE_C21, 1 hit
PS51657, PSRV_HELICASE, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative promoter usage. AlignAdd to basket
Isoform Genome polyprotein (identifier: Q91TW9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSFLRGGHL LSGVESLTPT THRDTITAPI VESLATPLRR SLERYPWSIP
60 70 80 90 100
KEFHSFLHTC GVDISGFGHA AHPHPVHKTI ETHLLLDVWP NYARGPSDVM
110 120 130 140 150
FIKPEKFAKL QSRQPNFAHL INYRLVPKDT TRYPSTSTNL PDCETVFMHD
160 170 180 190 200
ALMYYTPGQI ADLFFLCPQL QKIYASVVVP AESSFTHLSL HPEIYRFRFQ
210 220 230 240 250
GSDLVYEPEG NPAANYTQPR SALDWLQTTG FTVGHEFFSV TLLDSFGPVH
260 270 280 290 300
SLLIQRGRPP VFQAEDIASF RVPDAVALPA PASLHQDLRH RLVPRKVYDA
310 320 330 340 350
LFNYVRAVRL RVTDPAGFVR TQVGKPEYSW VTSSAWDNLQ HFALQTAAVR
360 370 380 390 400
PNTSHPLFQS PFARLSHWLR THTWALWCLA SPSASVSAWA TASALGRLLP
410 420 430 440 450
LHTDRLRLFG FDIIGRRFWP RLPFHGPEPR FLWETHPACR PPVLFADSAF
460 470 480 490 500
ECQILAGLAN RCSPSPFWSR LFPTASPPSW VAYSALALAA VPLAALALRW
510 520 530 540 550
FYGPDSPQAL HDQYHATFHP DPWTLDLPRR LRRFERESFM RTGSAPLPQS
560 570 580 590 600
LPPPEGSLLP VEPPPVPSDP EPALEPSPPA ASVPAPAPAL ASEPPPSPES
610 620 630 640 650
VAPSRRRRRA RRAAARAPSP SPALLGADLR FGDLPPVSAW DSDPEISKLG
660 670 680 690 700
ESTQGTVFAV TPGPRAPEPD TARLDADPSA SGPVMEFREL QKGAYIEPTG
710 720 730 740 750
AFLTRARNSV SSSIPYPTRA ACLLVAVSQA TGLPTRTLWA ALCANLPDSV
760 770 780 790 800
LDDGSLATLG LTTDHFAVLA RIFSLRCRFV SEHGDVELGL HDATSRFTIR
810 820 830 840 850
HTPGHFELVA DNFSLPALVG ASSVPGADLA EACKRFVAPD RTVLPFRDVH
860 870 880 890 900
IHRTDVRRAK NLISNMKNGF DGVMAQANPL DPKSARERFL MLDSCLDIAA
910 920 930 940 950
PRRVRLIHIA GFAGCGKSWP ISHLLRTPAF RVFKLAVPTT ELRDEWKALM
960 970 980 990 1000
DPRDQDKWRF GTWESSLLKT ARVLVIDEVY KMPRGYLDLA IHADAAIQFV
1010 1020 1030 1040 1050
ILLGDPIQGE YHSTHPSSSN ARLSPEHRYL RPYVDFYCFW SRRIPQNVAR
1060 1070 1080 1090 1100
VLDVPTTSTE MGFARYSQQF PFSGKILISA RDSAKSLADC GYHAVTIASS
1110 1120 1130 1140 1150
QGSTIAGPAY VHLDNHSRRL SHQHSLVAIT RSKSGIVFTG DKAAADGTSS
1160 1170 1180 1190 1200
ANLLFSAVLL DRRLSVRSLF SALLPCCPFV TEPPTSRAVL LRGAGYGIAR
1210 1220 1230 1240 1250
PLRARDAPPL GPDYVGDVIL DSSAPILGDG SANAPQVSTH FLPETRRPLH
1260 1270 1280 1290 1300
FDIPSARHQV ADHPLAPDHS ACAIEPVYPG ESFESLASLF LPPTDAESKE
1310 1320 1330 1340 1350
TYFRGEMSNQ FPHLDKPFEL GAQTSSLLAP LHNSKHDPTL LPASIGKRLR
1360 1370 1380 1390 1400
FRHSEAPYVI APRDEILGSL LYEAWCRAYH RSPRDVEPFD PDLYAECINL
1410 1420 1430 1440 1450
NEFAQLSSKT QATIMANANR SDPDWRWSAV RIFAKTQHKV NEGSLFGSWK
1460 1470 1480 1490 1500
ACQTLALMHD AVVLLLGPVK KYQRFFDQRD RPSTLYVHAG HTPFEMADWC
1510 1520 1530 1540 1550
RAHLTPAVKL ANDYTAFDQS QHGEAVVFER YKMNRLSIPA ELVDLHVYLK
1560 1570 1580 1590 1600
TNVSTQFGPL TCMRLTGEPG TYDDNTDYNI AVLHLEYAVG STPLMVSGDD
1610 1620 1630 1640 1650
SLLDSEPPVR DQWSAIAPML ALTFKKERGR YATFCGYYVG FTGAVRSPPA
1660 1670 1680 1690 1700
LFAKLMIAVD DGSISDKLIA YLTEFTVGHS SGDAFWTILP VEAVPYQSAC
1710 1720 1730 1740 1750
FDFFCRRAPA QAKVMLRLGE APESLLSLAF EGLKWASHSV YALMNSSHRR
1760 1770 1780 1790 1800
QLLHSSRRPR SLPEDPEVSQ LQGELLHQFQ SLHLPLRGGH MPNPLAAPFR
1810 1820 1830 1840 1850
LLQQSSSLGP TYAVAPIARA PQVPPPSMAD NATQVGPVPP RDDRVDRQPP
1860 1870 1880 1890 1900
LPDPPRVLET APSHFLDLPF QWKVTDFTGY AAYHGTDDLV ASAVLTTLCA
1910 1920 1930 1940 1950
PYRHAELLYV EISVAPCPPS FSKPIMFTVV WTPATLSPRD GKETDYYGGR
1960 1970 1980 1990 2000
QITVGGPVML SSTTAVPADL ARMNPFIKSS VSYNDTPRWT MSVPAVTGGD
2010 2020
TKIPLATAFV RGIVRVRAPS GAATPSA
Length:2,027
Mass (Da):223,738
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i77B46DC9950B0BF7
GO
Isoform Subgenomic capsid protein CP2 (identifier: Q91TW9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1827: Missing.

Show »
Length:200
Mass (Da):21,500
Checksum:iC931BF8A03D7DD46
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0402861 – 1827Missing in isoform Subgenomic capsid protein CP2. CuratedAdd BLAST1827

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF265566 Genomic RNA Translation: AAK52838.1

NCBI Reference Sequences

More...
RefSeqi
NP_115454.1, NC_002786.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
921087

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:921087

Keywords - Coding sequence diversityi

Alternative promoter usage

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF265566 Genomic RNA Translation: AAK52838.1
RefSeqiNP_115454.1, NC_002786.1

3D structure databases

SMRiQ91TW9
ModBaseiSearch...

Genome annotation databases

GeneIDi921087
KEGGivg:921087

Family and domain databases

Gene3Di2.60.120.20, 1 hit
3.40.50.300, 1 hit
3.90.70.100, 1 hit
InterProiView protein in InterPro
IPR027351, (+)RNA_virus_helicase_core_dom
IPR002588, Alphavirus-like_MT_dom
IPR043502, DNA/RNA_pol_sf
IPR027417, P-loop_NTPase
IPR008043, Peptidase_C21
IPR007094, RNA-dir_pol_PSvirus
IPR043629, Salyut_dom
IPR000574, Tymo_coat
IPR001788, Tymovirus_RNA-dep_RNA_pol
IPR043181, TYMV_endopept_dom
IPR029053, Viral_coat
PfamiView protein in Pfam
PF05381, Peptidase_C21, 1 hit
PF00978, RdRP_2, 1 hit
PF19227, Salyut, 1 hit
PF00983, Tymo_coat, 1 hit
PF01443, Viral_helicase1, 1 hit
PF01660, Vmethyltransf, 1 hit
SUPFAMiSSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS51743, ALPHAVIRUS_MT, 1 hit
PS51738, PEPTIDASE_C21, 1 hit
PS51657, PSRV_HELICASE, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOLG_MRFVC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91TW9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: December 1, 2001
Last modified: September 29, 2021
This is version 91 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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