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Entry version 98 (02 Dec 2020)
Sequence version 1 (01 Dec 2001)
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Protein

Genome polyprotein

Gene
N/A
Organism
Rice tungro spherical virus (strain Vt6) (RTSV) (Rice tungro spherical waikavirus)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Picornain 3C-like protease is a thiol protease that probably cleaves the polyprotein.By similarity

Miscellaneous

The Vt6 strain is a highly virulent strain.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei2677For picornain 3C-like protease activityPROSITE-ProRule annotation1
Active sitei2714For picornain 3C-like protease activityPROSITE-ProRule annotation1
Active sitei2808For picornain 3C-like protease activityPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1774 – 1781ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Thiol protease, Transferase
Biological processViral RNA replication
LigandATP-binding, Nucleotide-binding

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C03.024

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 7 chains:
Capsid protein 1
Short name:
CP-1
Alternative name(s):
22.5 kDa protein
Coat protein 1
Capsid protein 2
Short name:
CP-2
Alternative name(s):
26 kDa protein
Coat protein 2
Capsid protein 3
Short name:
CP-3
Alternative name(s):
31 kDa protein
Coat protein 3
Putative helicase (EC:3.6.4.-)
Alternative name(s):
Putative NTP-binding protein
Probable picornain 3C-like protease (EC:3.4.22.-)
Short name:
3C-like protease
Probable RNA-directed RNA polymerase (EC:2.7.7.48)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRice tungro spherical virus (strain Vt6) (RTSV) (Rice tungro spherical waikavirus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri337080 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaOrthornaviraePisuviricotaPisoniviricetesPicornaviralesSecoviridaeWaikavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiOryza sativa (Rice) [TaxID: 4530]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007184 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1493 – 1513HelicalSequence analysisAdd BLAST21
Transmembranei1592 – 1612HelicalSequence analysisAdd BLAST21
Transmembranei2360 – 2380HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Capsid protein, Host membrane, Membrane, Virion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2763C → W: Complete loss of cleavage between 3C-like protease and RNA-directed RNA polymerase. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000411471 – 641Putative leader proteinSequence analysisAdd BLAST641
ChainiPRO_0000041148642 – 849Capsid protein 1By similarityAdd BLAST208
ChainiPRO_0000041149850 – 1052Capsid protein 2By similarityAdd BLAST203
ChainiPRO_00000411501053 – ?1367Capsid protein 3By similarityAdd BLAST315
ChainiPRO_0000041151?1368 – 2523Putative helicaseSequence analysisAdd BLAST1156
ChainiPRO_00000411522524 – ?2849Probable picornain 3C-like proteaseBy similarityAdd BLAST326
ChainiPRO_0000041153?2850 – 3471Probable RNA-directed RNA polymeraseBy similarityAdd BLAST622

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Specific enzymatic cleavages by picornain 3C-like protease in vivo yield mature proteins (By similarity). Picornain 3C-like protease is autocatalytically processed.By similarity1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei641 – 642CleavageBy similarity2
Sitei849 – 850CleavageBy similarity2
Sitei1052 – 1053CleavageBy similarity2
Sitei2523 – 2524CleavageBy similarity2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1748 – 1914SF3 helicasePROSITE-ProRule annotationAdd BLAST167
Domaini2629 – 2847Peptidase C3PROSITE-ProRule annotationAdd BLAST219
Domaini3152 – 3283RdRp catalyticPROSITE-ProRule annotationAdd BLAST132

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili513 – 603Sequence analysisAdd BLAST91

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00205, rhv_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.10.10, 2 hits
2.60.120.20, 3 hits
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR044067, PCV_3C_PRO
IPR024387, Pept_C3G_Picornavir
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR001676, Picornavirus_capsid
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR033703, Rhv-like
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus
IPR029053, Viral_coat
IPR024379, Waikavirus_capsid-1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12381, Peptidase_C3G, 1 hit
PF00680, RdRP_1, 1 hit
PF00073, Rhv, 1 hit
PF00910, RNA_helicase, 1 hit
PF12264, Waikav_capsid_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q91PP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSFLLSSKN QAKLLHAGLE FVGGVRCAHQ GWVSGKAVVF CNYCNFAHRL
60 70 80 90 100
YRFYTKNHCV LNKETIENLC GRSFVSLYRA GLLLDDFTID DLLGKGKYAK
110 120 130 140 150
GSIDNLSIPF DDCALCPNAG TRLSQTGVSH DHFVCNYVEH LFECASFSRE
160 170 180 190 200
TGGKFIRACS KGWHWNATCT TCGASCRFAN PRENVVIAIF MNFLRVMYDG
210 220 230 240 250
NKYYVSLHCD TEWIPVHPLF ARLVLMVRGF APLDNSHVIE EDEMDICGHP
260 270 280 290 300
SEVTYDDPSN YAFSHQHVTR GVGMGHLAFC RDANGVDRGE HKFYLHGPFD
310 320 330 340 350
LKMTHAMFRV FMILLNCHGY VQSEFREEHP AVKDRSLCAL LSVAGLRGVN
360 370 380 390 400
IACNEEFIHL HSQFHNGSFR SQRPIPMVYA EPEMYPPLEY VRLTESWVPR
410 420 430 440 450
GRVMIDDLPS LLSRVYAESS QPHAGEIYEE IFDEDDLFEL GDDEGTSTRG
460 470 480 490 500
LLDLGRRLGG LLLGATKCVK GLHAVIEWPV DVLTKEAEDL GTWLADNKKY
510 520 530 540 550
VSESTWSCQV CPEVQDALEK SMREQAKLNA QVIGGIKKLA TTMDSATSKL
560 570 580 590 600
KDSLKELERR ISVLEQGVDE TQQARITNLE NFCEDAAKAF DALRADIDAL
610 620 630 640 650
KKKPAQSVTP LPSPSGNSGT AGEQRPPPRR RPPVVEMSEA QAGETVIVGG
660 670 680 690 700
DEEQEAHQDS SVAAAGPTDE HNAMLQKIYL GSFKWKVSDG GGSILKTFSL
710 720 730 740 750
PSDIWAANDR MKNFLSYFQY YTCEGMTFTL TITSIGLHGG TLLVAWDALS
760 770 780 790 800
SATRRGIVSM IQLSNLPSMT LHASGSSIGT LTVTSPAIQH QICTSGSEGS
810 820 830 840 850
IANLGSLVIS VANVLCADSA SAQELNVNAW VQFDKPKLSY WTAQHTIAQS
860 870 880 890 900
GGFEESQDLG DLQAIIATGK WSTTSDKNLM EIIVHPTACY VSEKLIYQTN
910 920 930 940 950
LSVVAHMFAK WSGSMKYTFV FGASMFDRGK IMVSAVPVQF RNSKLTLSQM
960 970 980 990 1000
AAFPSMVCDL SVETREFTFE VPYISIGKMS LVCKDYLFDI SSYNADLVVS
1010 1020 1030 1040 1050
RLHVMILDPL VKTGNASNSI GFYVVAGPGK DFKLHQMCGV KSQFAHDVLT
1060 1070 1080 1090 1100
AQDFGRSLSC SRLLGNGFKE WCSRESLLMR IPLKNGKKRA FKYAVTPRMR
1110 1120 1130 1140 1150
TLPPEATSLS WLSQIFVEWR GSLTYTIHVQ SGSAIQHSYM RIWYDPNGKT
1160 1170 1180 1190 1200
DEKEIKFLDS AHPPAGIKVY HWDLKIGDSF RFTVPYCART EKLQIPKAYA
1210 1220 1230 1240 1250
STPYEWLTMY NGAVTIDLRS GADMELFVSI AGGDDFEMFE QTVPPKCGSV
1260 1270 1280 1290 1300
SDSYTVLSYA DDIKSVTEVP NKTTYLADEQ PTTSAPRTST VDTEEDPPTE
1310 1320 1330 1340 1350
GEIARTSNGT LVQYRGGAWK PMVERTPTMS KKQVGPELVA SDSHMYKCIK
1360 1370 1380 1390 1400
NMNKNVKILT DRQCTAKLAD IVDSTQGLVG SNSTFVEDLA VGAKQIRKFG
1410 1420 1430 1440 1450
ESLEVFEGSM SAAKTAELID NTHAAFSGPA DGSPISNVVQ LLLPMLSSIK
1460 1470 1480 1490 1500
GMSGKMESKM ASLTAMFQPC KKAITHLIER SFPYLACKGF KTDKWIWAAL
1510 1520 1530 1540 1550
ASILVGAALL HYYRSDLKFV KKWSVMCMII WAPLLAEKAY HLGTWIKEKF
1560 1570 1580 1590 1600
LKSLPRTRTI KDSCRKHSLA GAFECLASAS CAYIKDNWAK TMSSLLTILS
1610 1620 1630 1640 1650
VVASLVMWGK IPDDKEITSF ADKFHSIGKK GRSITNIIGG FEKITSVCKK
1660 1670 1680 1690 1700
WSETLVGWIV SNVSGGIPKE DLAMTAYLGF KIHDWVRETR DMALMENRFQ
1710 1720 1730 1740 1750
GFGGDEHLVR VRRLYGHSLK IDNALMEKQI VPDMQLSLII KECRQKCLEL
1760 1770 1780 1790 1800
MNESYTYKGM KQSRIDPLHV CMLGAPGVGK STIAHVVINN LLDHRGEPEV
1810 1820 1830 1840 1850
DRIYTRCCAD AYWSNYHQEP VILYDDLGAI KSNLRLSDYA EIMGIKTNDP
1860 1870 1880 1890 1900
FSVPMAAVED KGKHCTSKYV FSCTNVLNLD DTGDVVTKMA YYRRRNVLVK
1910 1920 1930 1940 1950
VERDPDVPKN EANPTEGLVF TVLGHDQNCQ GDPQFVVKEN WDEPFLREVD
1960 1970 1980 1990 2000
TEGWRFERVE YRTFLRFLCM YTDAYMYSQE QVLQGIKTFK MNPFAPEPEF
2010 2020 2030 2040 2050
AQAQSGEAAE CEIVEETQEI PGEAPQEVKE LAKIETAPNM DELVEAFNKL
2060 2070 2080 2090 2100
RVTPGHLNEI LRDGSGCYID EWAIAGPRWL SFHELLPFTC GCHHTRVCDF
2110 2120 2130 2140 2150
NIVYNNMCKA VRSQSVHFKY RANQAIKYAY THKLHSQCRY SIDFEKLREC
2160 2170 2180 2190 2200
NPLDVFVCVL SKYTADDHSF ERRCPKKMNV VRMQRPPVFE LKMRPPSDSV
2210 2220 2230 2240 2250
VVEDDQGQRA FEWPHLYTFL RYRAIEFKDD KGSLTVREDA SADVCPWNEF
2260 2270 2280 2290 2300
LKLPWLDGDQ LKSVLPAHLH RMVQARLEQV EIMEENGNYS GEMRNAIAEI
2310 2320 2330 2340 2350
KEYLDQDHQW VAALVLVACA VKERRKMTHD KLHRKSFNAL DRLDKWYTTT
2360 2370 2380 2390 2400
APKTSKKMKI LLAIGASVAV AGVAVGAVIL LQKTNLFGSK EDEEIEGEEG
2410 2420 2430 2440 2450
ETQASGAHES DGIVTQHLKR DIRPKMRVTY TDHHVAEAHE EKSTEKPRKP
2460 2470 2480 2490 2500
GNPTRKNFLG LSPGFAERGM GVTYEEHTPL KDALLDESNK VFRRKIVASV
2510 2520 2530 2540 2550
ESAVKQGGKA SKDSVLSQIS EWQDKVRATG VIAARQLEAS GSLKKIHNLN
2560 2570 2580 2590 2600
SRRTSSHVMP GLVVHDGTFE RSDEVDAELH RITIDEVKSC PKMIKEGVST
2610 2620 2630 2640 2650
LSVKKASVGV LALQKAESQL SFPFTSRAGV DRDLSMTNLI DTHMAGMSCI
2660 2670 2680 2690 2700
IISELGNVFR TFGVLRLCGT YVCMPAHYLD EITSEHTLYF VCPSKITQIQ
2710 2720 2730 2740 2750
LERHRVCLVN GFQETVVWDL GPSVPPSRNY IDFTAKADDW KNYKATSGAL
2760 2770 2780 2790 2800
VMSKYLVDSM LQCVHFLDSI ELTEANVSVP TSYYEANGGI HTIISGLRYR
2810 2820 2830 2840 2850
VHCMPGFCGA AIMRADATCY RKIIGMHVSG LRNKCMGYAE TLTQEHLMRA
2860 2870 2880 2890 2900
IETLKETGLL KHIPRGAIGA GEEKLPEHSK KQSLSLEGKG NLGIVGQLPA
2910 2920 2930 2940 2950
QLVPTSVTKT TICKSMIHGL IGEIKTEPSV LSAWDRRLPF PPGEWDPMKD
2960 2970 2980 2990 3000
AVKKYGSYIL PFPTEEIQEV ENFLIKKFRR KENSRRTRNV NSLEVGINGI
3010 3020 3030 3040 3050
DGSDFWSPIE MKTSPGYPYI LKRPSGAQGK KYLFEELEPY PSGRPKYAMK
3060 3070 3080 3090 3100
DPELIENYER IKEEVTSGVK PSIMTMECLK DERRKLAKIY EKPATRTFTI
3110 3120 3130 3140 3150
LSPEVNILFR QYFGDFAAMV MSTRREHFSQ VGINPESMEW SDLINSLLRV
3160 3170 3180 3190 3200
NTKGFAGDYS KFDGIGSPAI YHSIVNVVNA WYDDGEVNAR ARHSLISSIV
3210 3220 3230 3240 3250
HRDGICGDLI LRYSQGMPSG FAMTVIFNSF VNYYFMALAW MSTVGSSLLS
3260 3270 3280 3290 3300
PQGSCKDFDT YCKIVAYGDD NVVSVHEEFL DVYNLQTVAA YLSHFGVTYT
3310 3320 3330 3340 3350
DGDKNPIHMS KPYEDITKMS FLKRGFERVE SSGFLWKAPL DKTSIEERLN
3360 3370 3380 3390 3400
WIRDCPTPVE ALEQNIESAL HEAAIHGRDY FDDLVQRLNS ALKRVMLPPT
3410 3420 3430 3440 3450
DISFEECQAR WWASVTGDAL RAADYSSLVR RASSGHVEFN KKYRDMFRQQ
3460 3470
DLPLKEILMK SKPVALLDLE V
Length:3,471
Mass (Da):389,212
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82B008325F931FB3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB064963 Genomic RNA Translation: BAB61927.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB064963 Genomic RNA Translation: BAB61927.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

MEROPSiC03.024

Family and domain databases

CDDicd00205, rhv_like, 1 hit
Gene3Di2.40.10.10, 2 hits
2.60.120.20, 3 hits
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR044067, PCV_3C_PRO
IPR024387, Pept_C3G_Picornavir
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR001676, Picornavirus_capsid
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR033703, Rhv-like
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus
IPR029053, Viral_coat
IPR024379, Waikavirus_capsid-1
PfamiView protein in Pfam
PF12381, Peptidase_C3G, 1 hit
PF00680, RdRP_1, 1 hit
PF00073, Rhv, 1 hit
PF00910, RNA_helicase, 1 hit
PF12264, Waikav_capsid_1, 1 hit
SUPFAMiSSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOLG_RTSVT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q91PP5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: December 1, 2001
Last modified: December 2, 2020
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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