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Protein
Submitted name:

Integrin

Gene
N/A
Organism
Pleurodeles waltl (Iberian ribbed newt)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionIntegrinUniRule annotationSAAS annotationImported, ReceptorUniRule annotationSAAS annotation
Biological processCell adhesionUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
IntegrinImported
OrganismiPleurodeles waltl (Iberian ribbed newt)Imported
Taxonomic identifieri8319 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaCaudataSalamandroideaSalamandridaePleurodelinaePleurodeles

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei989 – 1013HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29UniRule annotationAdd BLAST29
ChainiPRO_500142627630 – 1045UniRule annotationAdd BLAST1016

Structurei

3D structure databases

ProteinModelPortaliQ91292
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati35 – 96FG-GAPPROSITE-ProRule annotationAdd BLAST62
Repeati107 – 168FG-GAPPROSITE-ProRule annotationAdd BLAST62
Repeati172 – 224FG-GAPPROSITE-ProRule annotationAdd BLAST53
Repeati236 – 290FG-GAPPROSITE-ProRule annotationAdd BLAST55
Repeati291 – 356FG-GAPPROSITE-ProRule annotationAdd BLAST66
Repeati357 – 414FG-GAPPROSITE-ProRule annotationAdd BLAST58
Repeati418 – 481FG-GAPPROSITE-ProRule annotationAdd BLAST64
Domaini466 – 911Integrin_alpha2InterPro annotationAdd BLAST446

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG006186

Family and domain databases

Gene3Di2.130.10.130, 1 hit
InterProiView protein in InterPro
IPR013517 FG-GAP
IPR013519 Int_alpha_beta-p
IPR000413 Integrin_alpha
IPR013649 Integrin_alpha-2
IPR018184 Integrin_alpha_C_CS
IPR028994 Integrin_alpha_N
IPR032695 Integrin_dom_sf
PfamiView protein in Pfam
PF01839 FG-GAP, 2 hits
PF00357 Integrin_alpha, 1 hit
PF08441 Integrin_alpha2, 1 hit
PRINTSiPR01185 INTEGRINA
SMARTiView protein in SMART
SM00191 Int_alpha, 5 hits
SUPFAMiSSF69179 SSF69179, 3 hits
PROSITEiView protein in PROSITE
PS51470 FG_GAP, 7 hits
PS00242 INTEGRIN_ALPHA, 1 hit

Sequencei

Sequence statusi: Complete.

Q91292-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRSLAAESL AISLARLAFL LPLLGPGISF NLAIDRPTVY SGNPGSCFGF
60 70 80 90 100
AVDFYAPDPT SVFLLVGAPK ANTSQAGIVE GGHVIKCGWK MNRDCQPIIF
110 120 130 140 150
DSRGNRDFAP NDPIEFKSHQ WFGASVRSKN DTILTCAPLY HWRTEKKQER
160 170 180 190 200
EPVGTCFLQD GTRIVEYAPC RSSSHSDAEG QGFCQGGFSI DFTKADRVLL
210 220 230 240 250
GGPGSFYWQG QLISDEVEEI LKKYDLGSYS IAYRNHLATR SAGAEFDDSY
260 270 280 290 300
LGYSVAVGDF NGDGTEDFVS GVPRAARTLG MVSVFDGKSM TSLVNFTGEQ
310 320 330 340 350
MAAYFGYSVA ATDINGDGHV DLFVGAPLFL DRGSDGKLQE VGQVSVYLQQ
360 370 380 390 400
SIGLFQPVIK LNGFEIFARF GSCIAPLGDL DRDGFNDVPI GRPYGGDNKK
410 420 430 440 450
DSFIYNGRST GLNNMPSQAI EGQWASSTMP PSFGYSLKGG SDVDQNGYPD
460 470 480 490 500
LLIGVFGADK AVLYRSRSVI NVNAALEVSP SVLNPDNKLC SLPDGTKVSC
510 520 530 540 550
FKVKFCLKAD GKGSIPHDLT FQVELLLDKL KQKGAIRRAL FLHNRLSVHS
560 570 580 590 600
KNMTIQNRGS TQCEELDAYL RDDSEFRDKL TPINIFMDYH LDYKSAADST
610 620 630 640 650
GLQPILNQFT PANISRQAHI LLDVNDISVK PKLEVAVESE RKKIYIGDDN
660 670 680 690 700
PLTLVVTAQN QGEGAYEAEL IVQIPPQADF IGVVRNNESL SRLSCAFKTE
710 720 730 740 750
NKSRMVVCDL GNPMKARTKL VAGLRFSVHQ LSEMDNSVKF DLQIQSTNLY
760 770 780 790 800
DNLSPLQSYQ VDLAVLAAVE IRGVSTPDQI FLPIANWQPK TEPQIEDDIG
810 820 830 840 850
PLVQHIYELR NNGPSGFSKA ILNLQWPFKY KNDTLLYIIK YEIEGPMNCT
860 870 880 890 900
SDVEINPLNV KMSSTQEEEK NDTQGPADRN RHNINRRDTT SVKGDMETLA
910 920 930 940 950
CGNAECLQIA CQVGRLERGK SAILVVRSRL WTETFMKTEN QNHSFSLTSS
960 970 980 990 1000
ASFHVIVIEF PYTNLQIADI QNSTVVVTNI LWVNPTTNLP VWVIILAVLA
1010 1020 1030 1040
GLLLLSLLVF VMYKFGFFKR VRPPQEEQER EQLQPHENGE GTTDA
Length:1,045
Mass (Da):115,422
Last modified:November 1, 1996 - v1
Checksum:i4DB34B766B0C648E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81108 mRNA Translation: CAA57014.1
PIRiS60571

Similar proteinsi

Entry informationi

Entry nameiQ91292_PLEWA
AccessioniPrimary (citable) accession number: Q91292
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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