UniProtKB - Q91259 (Q91259_PETMA)
Protein
Adrenocorticotropic hormone
Gene
POM
Organism
Petromyzon marinus (Sea lamprey)
Status
Functioni
Stimulates the adrenal glands to release cortisol.ARBA annotation
GO - Molecular functioni
- hormone activity Source: UniProtKB-KW
Keywordsi
Molecular function | HormoneARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Adrenocorticotropic hormoneARBA annotationAlternative name(s): CorticotropinARBA annotation |
Gene namesi | Name:POMImported |
Organismi | Petromyzon marinus (Sea lamprey)Imported |
Taxonomic identifieri | 7757 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Cyclostomata › Hyperoartia › Petromyzontiformes › Petromyzontidae › Petromyzon |
Subcellular locationi
Extracellular region or secreted
- Secreted ARBA annotation
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 34 | Sequence analysisAdd BLAST | 34 | |
ChainiPRO_5010977060 | 35 – 245 | Adrenocorticotropic hormoneSequence analysisAdd BLAST | 211 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 108 – 125 | ACTH_domainInterPro annotationAdd BLAST | 18 | |
Domaini | 192 – 204 | ACTH_domainInterPro annotationAdd BLAST | 13 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 115 – 139 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the POMC family.ARBA annotation
Keywords - Domaini
SignalSequence analysisFamily and domain databases
InterProi | View protein in InterPro IPR013531, Mcrtin_ACTH_cent IPR001941, PMOC |
Pfami | View protein in Pfam PF00976, ACTH_domain, 2 hits |
PRINTSi | PR00383, MELANOCORTIN |
i Sequence
Sequence statusi: Complete.
Q91259-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATTSSAPTR SSSLPCRVAL LLSGLIALLG PAASRSAPLV CLQACESCLE
60 70 80 90 100
PAQPEPLCWM QCLGECSRLA APSADGSEIV LLGGGGGDEA PEGGEVSADK
110 120 130 140 150
RVQESADGYR MQHFRWGQPL PGKKRQPEQS QGVPLGMGSD ENARVVNGGQ
160 170 180 190 200
AWDEGWTLDD QANEVNARQW SAAPSKKDST PLSMQKENPE LYQMNHFRWG
210 220 230 240
QPPTHFKQKR YGGFMRKSPG YAHLKPLVTF FRDVMKNDSP TMLNN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D55629 mRNA Translation: BAA09492.1 AB206465 Genomic DNA Translation: BAE16562.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D55629 mRNA Translation: BAA09492.1 AB206465 Genomic DNA Translation: BAE16562.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
InterProi | View protein in InterPro IPR013531, Mcrtin_ACTH_cent IPR001941, PMOC |
Pfami | View protein in Pfam PF00976, ACTH_domain, 2 hits |
PRINTSi | PR00383, MELANOCORTIN |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q91259_PETMA | |
Accessioni | Q91259Primary (citable) accession number: Q91259 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | October 7, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |