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Protein
Submitted name:

Prospero-related homeodomain protein 1

Gene

prox1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • forebrain neuron development Source: ZFIN
  • lymphangiogenesis Source: ZFIN
  • myofibril assembly Source: ZFIN
  • negative regulation of DNA binding transcription factor activity Source: ZFIN
  • neuromast deposition Source: ZFIN
  • neuromast hair cell differentiation Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Prospero-related homeodomain protein 1Imported
Gene namesi
Name:prox1aImported
Synonyms:prox1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-397 prox1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

ELMiQ90ZL7

Structurei

3D structure databases

ProteinModelPortaliQ90ZL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini579 – 737ProsperoInterPro annotationAdd BLAST159

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili229 – 256Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxImported

Phylogenomic databases

eggNOGiKOG3779 Eukaryota
ENOG410ZE21 LUCA
HOVERGENiHBG053693
KOiK20211

Family and domain databases

Gene3Di1.10.10.500, 1 hit
InterProiView protein in InterPro
IPR023082 Homeo_prospero_dom
IPR037131 Homeo_prospero_dom_sf
IPR009057 Homeobox-like_sf
IPR039350 Prospero_homeodomain
IPR007738 Prox1
PANTHERiPTHR12198 PTHR12198, 1 hit
PTHR12198:SF6 PTHR12198:SF6, 1 hit
PfamiView protein in Pfam
PF05044 HPD, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51818 HOMEO_PROSPERO, 1 hit

Sequencei

Sequence statusi: Complete.

Q90ZL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDHDSTSLL SRQTKRRRVD IGVKRTVGQA SVVFTRAKAT FLSAMNPHGS
60 70 80 90 100
EQDVECSVVQ HADGEKSNVL RKLLKRANSY EDAVMPFPGA TIISQLLKNN
110 120 130 140 150
LTKNGGSEPN FQGSGLSSTG SEMQQEDACS NSSRGSPQEC LSPFSRPSMT
160 170 180 190 200
QFEMERLTDE HLRAKRARVE NIIRGMSHSP SVTLRAGDND REGAAQPPSP
210 220 230 240 250
RENYRENKRK QKLPQQQQQS FQQLVSARKE QKHEERRQLK LQLEDMQKQL
260 270 280 290 300
RQLQEKFYQI YDSTDSENDE DGNLSEDSMR SDGMDNRAHD SVPDRSDNEM
310 320 330 340 350
SDLDPGHFLD RARALIREQS MMEGDKPKRD GSRGKSQGPT SMHAEGKQLA
360 370 380 390 400
ETLKQELNTA MSQVVDTVVK VFAKPPRPVP QVFPPLHMES PDRFAVNGEN
410 420 430 440 450
PNFHTANQRL QCFGDVIIPN PLDTFGSMQV PNSNDQTEAL PLVVRKNSSD
460 470 480 490 500
QTGSLSTPGG HHHHPSLHPP PLSSTMGFSP PSFRHPFPLP LMGYPFQSPL
510 520 530 540 550
GAPTGPYPGK DRSSPESLDL SRETTSLRTK MSSNHLSHHR SISPTHPGNE
560 570 580 590 600
GLSLSLIKSE CGDLQDMSDI SPYSGSTIQE GLSPNHLKKA KLMFFYTRYP
610 620 630 640 650
SSNMLKMFFS DVKFNRCITS QLIKWFSNFR EFYYIQMEKF ARQAINDGVT
660 670 680 690 700
GSEELSVSRD CELFRALNMH YNKANDFEVP ERFLEVAQIT LREFFNAIVA
710 720 730
GKDVDPSWKK AIYKVICKLD SEVPEIFKSP NCLQELLHE
Length:739
Mass (Da):83,214
Last modified:December 1, 2001 - v1
Checksum:iB01AC5910ADB6CA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY032595 mRNA Translation: AAK40357.1
RefSeqiNP_571480.2, NM_131405.2
UniGeneiDr.81273

Genome annotation databases

GeneIDi30679
KEGGidre:30679

Similar proteinsi

Entry informationi

Entry nameiQ90ZL7_DANRE
AccessioniPrimary (citable) accession number: Q90ZL7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 18, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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