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Protein
Submitted name:

Cyclin-dependent kinase inhibitor 1Bb

Gene

cdkn1bb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-176408 Regulation of APC/C activators between G1/S and early anaphase
R-DRE-187577 SCF(Skp2)-mediated degradation of p27/p21
R-DRE-198323 AKT phosphorylates targets in the cytosol
R-DRE-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-DRE-2559586 DNA Damage/Telomere Stress Induced Senescence
R-DRE-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-DRE-69202 Cyclin E associated events during G1/S transition
R-DRE-69231 Cyclin D associated events in G1
R-DRE-69563 p53-Dependent G1 DNA Damage Response
R-DRE-69656 Cyclin A:Cdk2-associated events at S phase entry
R-DRE-8849470 PTK6 Regulates Cell Cycle

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase inhibitor 1BbImported
Submitted name:
Cyclin-dependent kinase inhibitor 1b (P27, kip1)Imported
Submitted name:
p27-like cyclin-dependent kinase inhibitorImported
Gene namesi
Name:cdkn1bbImported
Synonyms:cdkn1bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 25

Organism-specific databases

ZFINiZDB-GENE-030521-13 cdkn1bb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000054271

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105536

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 58Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4743 Eukaryota
ENOG410XXN5 LUCA
GeneTreeiENSGT00530000063588
HOGENOMiHOG000294081
HOVERGENiHBG073988
KOiK06624
OMAiYPKPSAC
OrthoDBiEOG091G19PZ
TreeFamiTF101111

Family and domain databases

InterProiView protein in InterPro
IPR003175 CDI
IPR029843 CDKN1B
PANTHERiPTHR10265 PTHR10265, 1 hit
PTHR10265:SF9 PTHR10265:SF9, 1 hit
PfamiView protein in Pfam
PF02234 CDI, 1 hit

Sequencei

Sequence statusi: Complete.

Q90YX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVRLSNGS PTLERMEARL SDQPKPSACR NLFGPVDHEE LKKDFQRQLR
60 70 80 90 100
TMEDASAEAW NFDFSTHTPR ADGRYQWEAL DIRSVPGFYS RSERGKGSDI
110 120 130 140 150
HISSSGNNND NNVDVNGNHD CRVTEQSAET PETLREPRKR SSCLDSSCQS
160 170
KRSHICVDEV TRTPRKPKKP RKPLSPTPT
Length:179
Mass (Da):20,285
Last modified:December 1, 2001 - v1
Checksum:i146127967F3E6F30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR354430 Genomic DNA No translation available.
BC056519 mRNA Translation: AAH56519.1
BC064282 mRNA Translation: AAH64282.1
AF398516 mRNA Translation: AAK84219.1
RefSeqiNP_997957.1, NM_212792.2
UniGeneiDr.75267

Genome annotation databases

EnsembliENSDART00000076417; ENSDARP00000070891; ENSDARG00000054271
GeneIDi368329
KEGGidre:368329

Similar proteinsi

Entry informationi

Entry nameiQ90YX4_DANRE
AccessioniPrimary (citable) accession number: Q90YX4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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