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Protein
Submitted name:

Reverse transcriptase

Gene

pol

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionNucleotidyltransferase, RNA-directed DNA polymeraseSAAS annotationImported, Transferase
LigandMetal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Reverse transcriptaseImported
Gene namesi
Name:polImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesOrterviralesRetroviridaeOrthoretrovirinaeLentivirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 234Reverse transcriptaseInterPro annotationAdd BLAST191
Domaini434 – 557RNase HInterPro annotationAdd BLAST124

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR000477 RT_dom
IPR010659 RVT_connect
IPR010661 RVT_thumb
PfamiView protein in Pfam
PF00075 RNase_H, 1 hit
PF00078 RVT_1, 1 hit
PF06815 RVT_connect, 1 hit
PF06817 RVT_thumb, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit
PS50878 RT_POL, 1 hit

Sequencei

Sequence statusi: Fragment.

Q90EW8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PISPIETVPV KLKPGMDGPK VKQWPLTEEK IKALVEICTE MEKEGKISKI
60 70 80 90 100
GPENPYNTPV FAIKKKDSTK WRKLVDFREL NKRTQDFWEV QLGIPHPSGL
110 120 130 140 150
KKKKSVTVLD VGDAYFSVPL DKDFRKYTAF TIPSTNNETP GIRYQYNVLP
160 170 180 190 200
QGWKGSPAIF QSSMTKILEP FRKLNPDIVI YQYMDDLYVG SDLEIEQHRT
210 220 230 240 250
KIEELRQHLL GWGFTTPDKK HQKEPPFLWM GYELHPDKWT VQPIVLPEKD
260 270 280 290 300
SWTVNDIQKL VGKLNWASQI YAGIKVRQLC KLLRGAKALT EVIPLTKEAE
310 320 330 340 350
LELAENREIL KEPVHGVYYD PSKDLIAELQ KQGQGQWTYQ IYQEPFKNLK
360 370 380 390 400
TGKYARMRGA HTNDVKQLTE AVQKIATESI VIWGKTPKFK LPIQKETWET
410 420 430 440 450
WWTEYWQATW IPEWEFVNTP PLVKLWYQLE KXPIVGAETF YVDGAANRET
460 470 480 490 500
KLGKAGYVTN RGRQKVVSLX DTTNQKTELQ AIHLALQDSG LEVNIVTDSQ
510 520 530 540 550
YALGIIQAQP DKSESELVSQ IIEXLIKKEK VYLAWVPAHK GIGGNEQVDK
560
LVSTGIRKVL FLDGID
Length:566
Mass (Da):64,986
Last modified:December 1, 2001 - v1
Checksum:iBAD224EF4EB82B76
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei566Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY036094 Genomic RNA Translation: AAK61539.1
PIRiA47330
B47330
C47330
D47330
F47330

Similar proteinsi

Entry informationi

Entry nameiQ90EW8_9HIV1
AccessioniPrimary (citable) accession number: Q90EW8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 18, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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