Transforming growth factor-beta type III receptor

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• activin binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• coreceptor activity Source: Ensembl
• fibroblast growth factor binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• glycosaminoglycan binding Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• heparin binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• SMAD binding Source: Ensembl
• transforming growth factor beta-activated receptor activity Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• transforming growth factor beta binding Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• transforming growth factor beta receptor activity, type III Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• transforming growth factor beta receptor binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• type II transforming growth factor beta receptor binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

GO - Biological processⁱ

• angiogenesis Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• animal organ regeneration Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• BMP signaling pathway Source: Ensembl
• cardiac epithelial to mesenchymal transition Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• cell growth Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• cell migration Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• embryonic digestive tract development Source: AgBase <p>Inferred from Expression Pattern</p> <p>Covers cases where the annotation is inferred from the timing or location of expression of a gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iep">GO evidence code guide</a></p> Inferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
• embryonic organ development Source: AgBaseInferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• endothelial cell activation Source: AgBase <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • "TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart."
    Boyer A.S., Runyan R.B.
    Dev Dyn 221:454-459(2001) [PubMed] [Europe PMC] [Abstract]
• epithelial to mesenchymal transition Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• eye development Source: AgBaseInferred from expression patternⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• heart development Source: AgBaseInferred from direct assayⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• heart morphogenesis Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• immune response Source: Ensembl
• intracellular signal transduction Source: Ensembl
• kidney development Source: AgBaseInferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
• liver development Source: AgBaseInferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
• lung development Source: AgBaseInferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• mesenchymal cell differentiation Source: AgBaseInferred from mutant phenotypeⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• negative regulation of cell adhesion Source: AgBase <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#tas">GO evidence code guide</a></p> Traceable author statementⁱ
  • "Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart."
    Mercado-Pimentel M.E., Runyan R.B.
    Cells Tissues Organs 185:146-156(2007) [PubMed] [Europe PMC] [Abstract]
• negative regulation of cell-cell adhesion Source: AgBaseInferred from mutant phenotypeⁱ
  • "TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart."
    Boyer A.S., Runyan R.B.
    Dev Dyn 221:454-459(2001) [PubMed] [Europe PMC] [Abstract]
• negative regulation of cellular component movement Source: Ensembl
• negative regulation of transforming growth factor beta receptor signaling pathway Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• nervous system development Source: AgBaseInferred from expression patternⁱ
  • "Expression of the type III TGFbeta receptor during chick organogenesis."
    Olivey H.E., Barnett J.V., Ridley B.D.
    Anat Rec A Discov Mol Cell Evol Biol 272:383-387(2003) [PubMed] [Europe PMC] [Abstract]
• pathway-restricted SMAD protein phosphorylation Source: Ensembl
• positive regulation of cell migration Source: AgBaseInferred from mutant phenotypeⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• positive regulation of gene expression Source: AgBaseInferred from mutant phenotypeⁱ
  • "TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart."
    Boyer A.S., Runyan R.B.
    Dev Dyn 221:454-459(2001) [PubMed] [Europe PMC] [Abstract]
• positive regulation of transforming growth factor beta receptor signaling pathway Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• protein-containing complex assembly Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• regulation of protein binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• regulation of transforming growth factor beta receptor signaling pathway Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• response to follicle-stimulating hormone Source: Ensembl
• response to hypoxia Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• response to luteinizing hormone Source: Ensembl
• response to prostaglandin E Source: Ensembl
• transforming growth factor beta receptor complex assembly Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• transforming growth factor beta receptor signaling pathway Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• vasculogenesis Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Topology

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

GO - Molecular functionⁱ

• fibroblast growth factor binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• SMAD binding Source: Ensembl
• transforming growth factor beta binding Source: BHF-UCLInferred from direct assayⁱ
  • "Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart."
    Brown C.B., Boyer A.S., Runyan R.B., Barnett J.V.
    Science 283:2080-2082(1999) [PubMed] [Europe PMC] [Abstract]
• transforming growth factor beta receptor binding Source: AgBaseInferred from sequence alignmentⁱ
  • Ref.1

    "Cloning and developmental expression of the chick type II and type III TGF beta receptors."
    Barnett J.V., Moustakas A., Lin W., Wang X.F., Lin H.Y., Galper J.B., Maas R.L.
    Dev. Dyn. 199:12-27(1994) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE.
• type II transforming growth factor beta receptor binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Compositional bias

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MSSSCVTPVF ALMILCFADA GPVPRSECVL SPVNSSHPVH ALLESFTVLS 
        60         70         80         90        100
GCASRGTTGL PQEVHVLNLR NPDEGLDHHE REVTLHLTPI SSVHIHQKPL 
       110        120        130        140        150
VFLLNSPLPL VWKLKTERLA PGIRRVFFVS SGSIVWFEKG NFSLSAETEE 
       160        170        180        190        200
KNFPERNEHL LQWAQKEYGA VTSFTELKIS RNIYIKVGED QVFPPTCNIE 
       210        220        230        240        250
KNFLSLNYLA GYLQPKRAEG CLMSNLVQER EVHIIELITP NSNPYSAFQV 
       260        270        280        290        300
DIIVDIKPSQ PGAKLERNVV LILKCKKSVN WVIKSHDVQG KLEVITSNSI 
       310        320        330        340        350
GFGKETERSM TMSKSVIPDI PSSHESLIKW AYEHKYSPVT SYTKAPVANR 
       360        370        380        390        400
FHLQLEHTEE MNDEEDHSLP PELTELLHGA KNPALSDGLT FPFHINRGGH 
       410        420        430        440        450
ETGGEGIFPS RDSVDTLINH DFEHSLSKHK EPEEVQGSAD VALSIKCDDK 
       460        470        480        490        500
VMTVAVEKDS LQASGYTRTE LSLLDHSCKA RMNGTHFILE SLPNKCGTRT 
       510        520        530        540        550
SYILDKIVYF NSIVIQLSSP AEGSSFDDDD MESGDNGFPG DADEGDVTFS 
       560        570        580        590        600
NWPEIAFNCT LHQPEKDFFN PAMFWPPEPH ITNVTFNMEL YKTDLFLAPS 
       610        620        630        640        650
QGLFSVAENG PIYVEVSVTK ADISLGFAIQ TCFVSPFSNP DRMSDYTIIE 
       660        670        680        690        700
NICPKDESVK FYSTEKLNFP IAHAQKDKKR FSFVFKPIFN ISLLFLHCEL 
       710        720        730        740        750
TLCTNIDKDT QRLPKCVPPD EACTSLNVDM ILAMMHNKKT FTKPLVITHE 
       760        770        780        790        800
GKPEDSSLPK SNVRQPSVFY GLDTLTVVGI AFAAFVIGAL LTGALWFIYS 
       810        820        830        840 
HTGEAAGRRQ VPTSPPASEN SSAAHSIGST QSTPCSSSSA T          

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ