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Protein

Proteasome subunit beta type

Gene
N/A
Organism
Ginglymostoma cirratum (Nurse shark) (Squalus cirratus)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteaseUniRule annotation

Protein family/group databases

MEROPSiT01.012

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta typeUniRule annotation (EC:3.4.25.1UniRule annotation)
OrganismiGinglymostoma cirratum (Nurse shark) (Squalus cirratus)Imported
Taxonomic identifieri7801 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiGaleoideaOrectolobiformesGinglymostomatidaeGinglymostoma

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotationSAAS annotation, ProteasomeUniRule annotation

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ90571
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG108297

Family and domain databases

Gene3Di3.60.20.10, 1 hit
InterProiView protein in InterPro
IPR029055 Ntn_hydrolases_N
IPR000243 Pept_T1A_subB
IPR035705 Proteasome_beta8
IPR016050 Proteasome_bsu_CS
IPR001353 Proteasome_sua/b
IPR023333 Proteasome_suB-type
PANTHERiPTHR11599:SF53 PTHR11599:SF53, 1 hit
PfamiView protein in Pfam
PF00227 Proteasome, 1 hit
PRINTSiPR00141 PROTEASOME
SUPFAMiSSF56235 SSF56235, 1 hit
PROSITEiView protein in PROSITE
PS00854 PROTEASOME_BETA_1, 1 hit
PS51476 PROTEASOME_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q90571-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALMEVCGYQ DWSQDDLPLR EQKACLVKAK ELGPGARDGQ LVVPVGLDPV
60 70 80 90 100
EFLKPYSEGE DGVRIKLQHG TTTLAFKFQH GVIVAVDSRA SAGNYLASVD
110 120 130 140 150
ANKVIEINPY LLGTMSGSAA DCQYWERLLA KQCRLYKLRN KQRISVSAAS
160 170 180 190 200
KLLSNMMCEY RGMGLSMGSM ICGWDKKGPG LYYVDDNGTR LSGNMFSTGC
210 220 230 240 250
GNVYAYGVVD SGYRYDLTVE EAYDLGRRAI YHATHRDAYT GGFVNMYHMR
260 270
EDGWIKVSKD DVGELHFKYA AEKQNLAQ
Length:278
Mass (Da):30,926
Last modified:November 1, 1996 - v1
Checksum:iB7FB82DC2CBE256A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64057 mRNA Translation: BAA10934.1

Similar proteinsi

Entry informationi

Entry nameiQ90571_GINCI
AccessioniPrimary (citable) accession number: Q90571
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: December 20, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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