UniProtKB - Q8ZYK1 (Q8ZYK1_PYRAE)
Protein
ORC1-type DNA replication protein
Gene
PAE0737
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Functioni
Involved in regulation of DNA replication.UniRule annotationSAAS annotation
Sites
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| Binding sitei | 20 | ADP; via carbonyl oxygenCombined sources | 1 | |
| Binding sitei | 193 | ADPCombined sources | 1 | |
| Binding sitei | 193 | ATPUniRule annotation | 1 | |
| Binding sitei | 205 | ADPCombined sources | 1 | |
| Binding sitei | 205 | ATPUniRule annotation | 1 |
Regions
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| Nucleotide bindingi | 54 – 59 | ADPCombined sources | 6 | |
| Nucleotide bindingi | 55 – 59 | ATPUniRule annotation | 5 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
GO - Biological processi
- cell division Source: UniProtKB-KW
- DNA replication Source: UniProtKB-UniRule
Keywordsi
| Biological process | Cell cycle, Cell divisionImported, DNA replicationUniRule annotationSAAS annotation |
| Ligand | ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding |
Enzyme and pathway databases
| BioCyci | PAER178306:GCEO-512-MONOMER |
Names & Taxonomyi
| Protein namesi | Recommended name: ORC1-type DNA replication proteinUniRule annotation |
| Gene namesi | Ordered Locus Names:PAE0737Imported |
| Organismi | Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)Imported |
| Taxonomic identifieri | 178306 [NCBI] |
| Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum › |
| Proteomesi |
|
Structurei
3D structure databases
| ProteinModelPortali | Q8ZYK1 |
| ModBasei | Search... |
| MobiDBi | Search... |
Miscellaneous databases
| EvolutionaryTracei | Q8ZYK1 |
Family & Domainsi
Domains and Repeats
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| Domaini | 43 – 194 | AAAInterPro annotationAdd BLAST | 152 | |
| Domaini | 294 – 379 | Cdc6_CInterPro annotationAdd BLAST | 86 |
Sequence similaritiesi
Phylogenomic databases
| eggNOGi | arCOG00467 Archaea COG1474 LUCA |
| HOGENOMi | HOG000230140 |
| InParanoidi | Q8ZYK1 |
| KOi | K10725 |
| OMAi | YLFYENE |
| OrthoDBi | POG093Z03TQ |
Family and domain databases
| CDDi | cd08768 Cdc6_C, 1 hit |
| Gene3Di | 1.10.10.10, 1 hit |
| HAMAPi | MF_01407 ORC1_type_DNA_replic_protein, 1 hit |
| InterProi | View protein in InterPro IPR003593 AAA+_ATPase IPR015163 Cdc6_C IPR014277 Orc1/Cdc6_arc IPR027417 P-loop_NTPase IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf |
| Pfami | View protein in Pfam PF13401 AAA_22, 1 hit PF09079 Cdc6_C, 1 hit |
| SMARTi | View protein in SMART SM00382 AAA, 1 hit SM01074 Cdc6_C, 1 hit |
| SUPFAMi | SSF46785 SSF46785, 1 hit SSF52540 SSF52540, 1 hit |
| TIGRFAMsi | TIGR02928 TIGR02928, 1 hit |
Sequencei
Sequence statusi: Complete.
Q8ZYK1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAIVVDDSVF SPSYVPKRLP HREQQLQQLD ILLGNWLRNP GHHYPRATLL
60 70 80 90 100
GRPGTGKTVT LRKLWELYKD KTTARFVYIN GFIYRNFTAI IGEIARSLNI
110 120 130 140 150
PFPRRGLSRD EFLALLVEHL RERDLYMFLV LDDAFNLAPD ILSTFIRLGQ
160 170 180 190 200
EADKLGAFRI ALVIVGHNDA VLNNLDPSTR GIMGKYVIRF SPYTKDQIFD
210 220 230 240 250
ILLDRAKAGL AEGSYSEDIL QMIADITGAQ TPLDTNRGDA RLAIDILYRS
260 270 280 290 300
AYAAQQNGRK HIAPEDVRKS SKEVLFGISE EVLIGLPLHE KLFLLAIVRS
310 320 330 340 350
LKISHTPYIT FGDAEESYKI VCEEYGERPR VHSQLWSYLN DLREKGIVET
360 370 380
RQNKRGEGVR GRTTLISIGT EPLDTLEAVI TKLIKEELR
Sequence databases
| Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE009441 Genomic DNA Translation: AAL62992.1 |
Genome annotation databases
| EnsemblBacteriai | AAL62992; AAL62992; PAE0737 |
| KEGGi | pai:PAE0737 |
| PATRICi | fig|178306.9.peg.537 |
Similar proteinsi
Entry informationi
| Entry namei | Q8ZYK1_PYRAE | |
| Accessioni | Q8ZYK1Primary (citable) accession number: Q8ZYK1 | |
| Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2002 |
| Last sequence update: | March 1, 2002 | |
| Last modified: | July 18, 2018 | |
| This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
| Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |



