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UniProtKB - Q8ZR86 (ALLR_SALTY)
Protein
HTH-type transcriptional repressor AllR
Gene
allR
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Functioni
Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 207 | GlyoxylateBy similarity | 1 | |
Binding sitei | 217 | GlyoxylateBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 43 – 62 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: GO_Central
- DNA-binding transcription factor activity Source: GO_Central
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: GO_Central
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: HTH-type transcriptional repressor AllRAlternative name(s): Negative regulator of allantoin and glyoxylate utilization operons |
Gene namesi | Name:allR Ordered Locus Names:STM0516 |
Organismi | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
Taxonomic identifieri | 99287 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Salmonella › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000313705 | 1 – 272 | HTH-type transcriptional repressor AllRAdd BLAST | 272 |
Proteomic databases
PaxDbi | Q8ZR86 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 83 | HTH iclR-typePROSITE-ProRule annotationAdd BLAST | 63 | |
Domaini | 98 – 267 | IclR-EDPROSITE-ProRule annotationAdd BLAST | 170 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 154 – 156 | Glyoxylate bindingBy similarity | 3 | |
Regioni | 234 – 236 | Glyoxylate bindingBy similarity | 3 |
Phylogenomic databases
HOGENOMi | CLU_062618_7_1_6 |
OMAi | PKSSLYM |
PhylomeDBi | Q8ZR86 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8ZR86-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTEVRRRGRP GQAEPTAQKG AQALERGIAI LQYLERSGGS SSVSDISGSL
60 70 80 90 100
DLPLSTTFRL LKVLQAADFV YQDSQLGWWH IGLGVFNVGS AYIHNRDVLS
110 120 130 140 150
VAGPFMHRLM LLSGETVNVA IRNGNEAVLI GQKECKSMVR MCAPLGSRLP
160 170 180 190 200
LHASGAGKAL LYPLTEEELV GIVVNTGLRR FTPTTLVDLP ILLKNLEQAR
210 220 230 240 250
EQGYTVDQEE HVVGLNCIAS AIYDDAGSVV AAISISGPAS RLTEDRFISQ
260 270
GELVRDTAKD ISTALGLKPP VA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE006468 Genomic DNA Translation: AAL19470.1 |
RefSeqi | NP_459511.1, NC_003197.2 WP_000141265.1, NC_003197.2 |
Genome annotation databases
EnsemblBacteriai | AAL19470; AAL19470; STM0516 |
GeneIDi | 1252036 |
KEGGi | stm:STM0516 |
PATRICi | fig|99287.12.peg.550 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE006468 Genomic DNA Translation: AAL19470.1 |
RefSeqi | NP_459511.1, NC_003197.2 WP_000141265.1, NC_003197.2 |
3D structure databases
SMRi | Q8ZR86 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 99287.STM0516 |
Proteomic databases
PaxDbi | Q8ZR86 |
Genome annotation databases
EnsemblBacteriai | AAL19470; AAL19470; STM0516 |
GeneIDi | 1252036 |
KEGGi | stm:STM0516 |
PATRICi | fig|99287.12.peg.550 |
Phylogenomic databases
HOGENOMi | CLU_062618_7_1_6 |
OMAi | PKSSLYM |
PhylomeDBi | Q8ZR86 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ALLR_SALTY | |
Accessioni | Q8ZR86Primary (citable) accession number: Q8ZR86 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | March 1, 2002 | |
Last modified: | February 23, 2022 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |