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Protein

D-serine dehydratase

Gene

dsdA

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-3841-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:STM3802
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001856201 – 440D-serine dehydrataseAdd BLAST440

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei116N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PaxDbiQ8ZL08
PRIDEiQ8ZL08

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi99287.STM3802

Structurei

Secondary structure

1440
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ8ZL08
SMRiQ8ZL08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC Bacteria
COG3048 LUCA
HOGENOMiHOG000218072
KOiK01753
OMAiESDPNCF
PhylomeDBiQ8ZL08

Family and domain databases

HAMAPiMF_01030 D_Ser_dehydrat, 1 hit
InterProiView protein in InterPro
IPR011780 D_Ser_am_lyase
IPR001926 PLP-dep
IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052 Trypto_synt_PLP_dependent
PANTHERiPTHR43419:SF2 PTHR43419:SF2, 1 hit
PfamiView protein in Pfam
PF00291 PALP, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR02035 D_Ser_am_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00165 DEHYDRATASE_SER_THR, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZL08-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENIQKLIAR YPLVEDLVAL KETTWFNPGA TSLAQGLPYV GLTEQDVNAA
60 70 80 90 100
HDRLARFAPY LAKAFPQTAA AGGMIESDVV AIPAMQKRLE KEYGQTINGE
110 120 130 140 150
MLLKKDSHLA ISGSIKARGG IYEVLTHAEK LALEAGLLTT DDDYSVLLSP
160 170 180 190 200
EFKQFFSQYS IAVGSTGNLG LSIGIMSACI GFKVTVHMSA DARAWKKAKL
210 220 230 240 250
RSHGVTVVEY EDDYGVAVEQ GRKAAQSDPN CFFIDDENSR TLFLGYAVAG
260 270 280 290 300
QRLKAQFAQQ GRVVDASHPL FVYLPCGVGG GPGGVAFGLK LAFGDNVHCF
310 320 330 340 350
FAEPTHSPCM LLGVYTGLHD AISVQDIGID NLTAADGLAV GRASGFVGRA
360 370 380 390 400
MERLLDGLYT LDDQTMYDML GWLAQEEGIR LEPSALAGMA GPQRICASVA
410 420 430 440
YQQRHGFSQT QLGNATHLVW ATGGGMVPED EMEQYLAKGR
Length:440
Mass (Da):47,369
Last modified:March 1, 2002 - v1
Checksum:i488BB3561968D7C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA Translation: AAL22662.1
RefSeqiNP_462703.1, NC_003197.2
WP_000427997.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL22662; AAL22662; STM3802
GeneIDi1255329
KEGGistm:STM3802
PATRICifig|99287.12.peg.4023

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA Translation: AAL22662.1
RefSeqiNP_462703.1, NC_003197.2
WP_000427997.1, NC_003197.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3R0XX-ray1.93A1-440[»]
3R0ZX-ray2.40A1-440[»]
ProteinModelPortaliQ8ZL08
SMRiQ8ZL08
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM3802

Proteomic databases

PaxDbiQ8ZL08
PRIDEiQ8ZL08

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL22662; AAL22662; STM3802
GeneIDi1255329
KEGGistm:STM3802
PATRICifig|99287.12.peg.4023

Phylogenomic databases

eggNOGiENOG4105BZC Bacteria
COG3048 LUCA
HOGENOMiHOG000218072
KOiK01753
OMAiESDPNCF
PhylomeDBiQ8ZL08

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-3841-MONOMER

Family and domain databases

HAMAPiMF_01030 D_Ser_dehydrat, 1 hit
InterProiView protein in InterPro
IPR011780 D_Ser_am_lyase
IPR001926 PLP-dep
IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052 Trypto_synt_PLP_dependent
PANTHERiPTHR43419:SF2 PTHR43419:SF2, 1 hit
PfamiView protein in Pfam
PF00291 PALP, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR02035 D_Ser_am_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00165 DEHYDRATASE_SER_THR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSDHD_SALTY
AccessioniPrimary (citable) accession number: Q8ZL08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: March 1, 2002
Last modified: November 7, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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