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Protein

D-serine dehydratase

Gene

dsdA

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-3841-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:STM3802
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001856201 – 440D-serine dehydrataseAdd BLAST440

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei116N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PaxDbiQ8ZL08
PRIDEiQ8ZL08

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi99287.STM3802

Structurei

Secondary structure

1440
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 8Combined sources7
Helixi13 – 18Combined sources6
Beta strandi24 – 26Combined sources3
Helixi33 – 36Combined sources4
Helixi37 – 39Combined sources3
Helixi44 – 56Combined sources13
Helixi58 – 64Combined sources7
Helixi66 – 71Combined sources6
Beta strandi79 – 81Combined sources3
Helixi83 – 93Combined sources11
Beta strandi99 – 105Combined sources7
Helixi106 – 108Combined sources3
Beta strandi110 – 112Combined sources3
Helixi115 – 134Combined sources20
Helixi144 – 148Combined sources5
Helixi150 – 156Combined sources7
Beta strandi160 – 164Combined sources5
Helixi168 – 180Combined sources13
Beta strandi183 – 189Combined sources7
Helixi194 – 201Combined sources8
Turni202 – 204Combined sources3
Beta strandi206 – 212Combined sources7
Helixi214 – 226Combined sources13
Beta strandi231 – 234Combined sources4
Turni236 – 238Combined sources3
Helixi240 – 247Combined sources8
Helixi249 – 260Combined sources12
Beta strandi265 – 268Combined sources4
Beta strandi270 – 275Combined sources6
Beta strandi277 – 279Combined sources3
Helixi280 – 293Combined sources14
Helixi294 – 296Combined sources3
Beta strandi297 – 304Combined sources8
Helixi309 – 316Combined sources8
Helixi319 – 321Combined sources3
Helixi325 – 327Combined sources3
Helixi336 – 338Combined sources3
Helixi346 – 351Combined sources6
Helixi352 – 354Combined sources3
Beta strandi356 – 361Combined sources6
Helixi363 – 377Combined sources15
Helixi383 – 390Combined sources8
Helixi391 – 397Combined sources7
Helixi399 – 404Combined sources6
Helixi409 – 412Combined sources4
Beta strandi416 – 421Combined sources6
Helixi429 – 437Combined sources9

3D structure databases

ProteinModelPortaliQ8ZL08
SMRiQ8ZL08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC Bacteria
COG3048 LUCA
HOGENOMiHOG000218072
KOiK01753
OMAiESDPNCF
PhylomeDBiQ8ZL08

Family and domain databases

HAMAPiMF_01030 D_Ser_dehydrat, 1 hit
InterProiView protein in InterPro
IPR011780 D_Ser_am_lyase
IPR001926 PLP-dep
IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052 Trypto_synt_PLP_dependent
PANTHERiPTHR43419:SF2 PTHR43419:SF2, 1 hit
PfamiView protein in Pfam
PF00291 PALP, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR02035 D_Ser_am_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00165 DEHYDRATASE_SER_THR, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZL08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENIQKLIAR YPLVEDLVAL KETTWFNPGA TSLAQGLPYV GLTEQDVNAA
60 70 80 90 100
HDRLARFAPY LAKAFPQTAA AGGMIESDVV AIPAMQKRLE KEYGQTINGE
110 120 130 140 150
MLLKKDSHLA ISGSIKARGG IYEVLTHAEK LALEAGLLTT DDDYSVLLSP
160 170 180 190 200
EFKQFFSQYS IAVGSTGNLG LSIGIMSACI GFKVTVHMSA DARAWKKAKL
210 220 230 240 250
RSHGVTVVEY EDDYGVAVEQ GRKAAQSDPN CFFIDDENSR TLFLGYAVAG
260 270 280 290 300
QRLKAQFAQQ GRVVDASHPL FVYLPCGVGG GPGGVAFGLK LAFGDNVHCF
310 320 330 340 350
FAEPTHSPCM LLGVYTGLHD AISVQDIGID NLTAADGLAV GRASGFVGRA
360 370 380 390 400
MERLLDGLYT LDDQTMYDML GWLAQEEGIR LEPSALAGMA GPQRICASVA
410 420 430 440
YQQRHGFSQT QLGNATHLVW ATGGGMVPED EMEQYLAKGR
Length:440
Mass (Da):47,369
Last modified:March 1, 2002 - v1
Checksum:i488BB3561968D7C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA Translation: AAL22662.1
RefSeqiNP_462703.1, NC_003197.2
WP_000427997.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL22662; AAL22662; STM3802
GeneIDi1255329
KEGGistm:STM3802
PATRICifig|99287.12.peg.4023

Entry informationi

Entry nameiSDHD_SALTY
AccessioniPrimary (citable) accession number: Q8ZL08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: March 1, 2002
Last modified: February 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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