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Entry version 99 (17 Jun 2020)
Sequence version 1 (01 Mar 2002)
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Protein

Anti-FlhC(2)FlhD(4) factor YdiV

Gene

ydiV

Organism
Salmonella typhi
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as an anti-FlhC2FlhD4 factor by binding to FlhD, decreasing its ability to bind DNA, and thus negatively regulates expression of flagellar class II operons, decreasing motility in nutrient-poor medium. Required for resistance to host phagocyte oxidase (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation, Virulence

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
GCF_001048035:AC754_RS12270-MONOMER
GCF_001048375:AC768_RS13490-MONOMER
GCF_001079465:ADV44_RS10035-MONOMER
GCF_001088345:AEZ18_RS14900-MONOMER
GCF_001095585:AD238_RS13870-MONOMER
GCF_001104165:AE704_RS13495-MONOMER
GCF_001104885:AEZ38_RS14220-MONOMER
GCF_001106745:AE121_RS10050-MONOMER
GCF_001119245:AE140_RS11105-MONOMER
GCF_001121865:AE338_RS14455-MONOMER
GCF_001127485:AE735_RS11355-MONOMER
GCF_001135805:AEG73_RS13715-MONOMER
GCF_001148125:AEN24_RS08315-MONOMER
GCF_001148305:AEN67_RS12870-MONOMER
GCF_001157245:AER93_RS13735-MONOMER
GCF_001163025:AFA50_RS13505-MONOMER
GCF_001240865:ALC23_RS14755-MONOMER
GCF_001356455:AQJ76_RS13490-MONOMER
GCF_001357935:AQL34_RS24415-MONOMER
GCF_001359015:AQL50_RS24225-MONOMER
GCF_001360555:AQK88_RS13495-MONOMER
GCF_001361075:AQM75_RS10780-MONOMER
GCF_001362095:AQO19_RS11535-MONOMER
GCF_001362135:AQN73_RS14840-MONOMER
GCF_001362175:AQN68_RS13495-MONOMER
GCF_001362195:AQN87_RS01495-MONOMER
GCF_001362335:AQN99_RS12850-MONOMER
GCF_001364695:AQQ97_RS24835-MONOMER
GCF_900185485:CDZ80_RS10425-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Anti-FlhC(2)FlhD(4) factor YdiV
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ydiV
Ordered Locus Names:STY1766, t1225
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmonella typhi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri90370 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002670 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003468691 – 237Anti-FlhC(2)FlhD(4) factor YdiVAdd BLAST237

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FlhD in the FlhC2FlhD4 heterohexamer, inhibiting its ability to activate transcription.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
220341.16502846

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8Z6I7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 237EALAdd BLAST237

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the YdiV family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4108TC0 Bacteria
COG2200 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_089254_1_1_6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.450, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001633 EAL_dom
IPR035919 EAL_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00563 EAL, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141868 SSF141868, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8Z6I7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIASLDELYH SELFFLPVMD ENARLVGLEI IATFAAEDGA VRMPTELVAP
60 70 80 90 100
RLSVEEQYCL FVEKLALLET CQHFFIQHKL IAWLNLPPAI SDLLLLDSEL
110 120 130 140 150
FSRAARFPFF EVAINENYPG LNQGKNNETL ANLAMHFPLI LANFGAGEAS
160 170 180 190 200
TKAIFDGLFK RVMLDKNFIQ QRAEMISFEP FMHAIVAQIS SSCESLMIAG
210 220 230
IDTEAMFARA APLGFSAFQG GLWPPVPVSQ LIKLVQR
Length:237
Mass (Da):26,426
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i638213CE47E10E21
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014613 Genomic DNA Translation: AAO68880.1
AL513382 Genomic DNA Translation: CAD02008.1

NCBI Reference Sequences

More...
RefSeqi
NP_456167.1, NC_003198.1
WP_000561998.1, NZ_WNTL01000016.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO68880; AAO68880; t1225
CAD02008; CAD02008; CAD02008

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1248137

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
stt:t1225
sty:STY1766

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|220341.7.peg.1778

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014613 Genomic DNA Translation: AAO68880.1
AL513382 Genomic DNA Translation: CAD02008.1
RefSeqiNP_456167.1, NC_003198.1
WP_000561998.1, NZ_WNTL01000016.1

3D structure databases

SMRiQ8Z6I7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi220341.16502846

Genome annotation databases

EnsemblBacteriaiAAO68880; AAO68880; t1225
CAD02008; CAD02008; CAD02008
GeneIDi1248137
KEGGistt:t1225
sty:STY1766
PATRICifig|220341.7.peg.1778

Phylogenomic databases

eggNOGiENOG4108TC0 Bacteria
COG2200 LUCA
HOGENOMiCLU_089254_1_1_6

Enzyme and pathway databases

BioCyciGCF_001048035:AC754_RS12270-MONOMER
GCF_001048375:AC768_RS13490-MONOMER
GCF_001079465:ADV44_RS10035-MONOMER
GCF_001088345:AEZ18_RS14900-MONOMER
GCF_001095585:AD238_RS13870-MONOMER
GCF_001104165:AE704_RS13495-MONOMER
GCF_001104885:AEZ38_RS14220-MONOMER
GCF_001106745:AE121_RS10050-MONOMER
GCF_001119245:AE140_RS11105-MONOMER
GCF_001121865:AE338_RS14455-MONOMER
GCF_001127485:AE735_RS11355-MONOMER
GCF_001135805:AEG73_RS13715-MONOMER
GCF_001148125:AEN24_RS08315-MONOMER
GCF_001148305:AEN67_RS12870-MONOMER
GCF_001157245:AER93_RS13735-MONOMER
GCF_001163025:AFA50_RS13505-MONOMER
GCF_001240865:ALC23_RS14755-MONOMER
GCF_001356455:AQJ76_RS13490-MONOMER
GCF_001357935:AQL34_RS24415-MONOMER
GCF_001359015:AQL50_RS24225-MONOMER
GCF_001360555:AQK88_RS13495-MONOMER
GCF_001361075:AQM75_RS10780-MONOMER
GCF_001362095:AQO19_RS11535-MONOMER
GCF_001362135:AQN73_RS14840-MONOMER
GCF_001362175:AQN68_RS13495-MONOMER
GCF_001362195:AQN87_RS01495-MONOMER
GCF_001362335:AQN99_RS12850-MONOMER
GCF_001364695:AQQ97_RS24835-MONOMER
GCF_900185485:CDZ80_RS10425-MONOMER

Family and domain databases

Gene3Di3.20.20.450, 1 hit
InterProiView protein in InterPro
IPR001633 EAL_dom
IPR035919 EAL_sf
PfamiView protein in Pfam
PF00563 EAL, 1 hit
SUPFAMiSSF141868 SSF141868, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYDIV_SALTI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8Z6I7
Secondary accession number(s): Q7CA76
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: March 1, 2002
Last modified: June 17, 2020
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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