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Entry version 118 (10 Feb 2021)
Sequence version 1 (01 Mar 2002)
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Protein
Submitted name:

Hcp1 family type VI secretion system effector

Gene

hcp

Organism
Salmonella typhi
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Hcp1 family type VI secretion system effectorImported
Submitted name:
Type VI secretion system tube protein HcpImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:hcpImported
Ordered Locus Names:STY3300Imported, t3052Imported
ORF Names:CAJ76_04465Imported, CAJ80_23245Imported, CAJ85_02535Imported, CAL67_22615Imported, CB224_02975Imported, CC884_02630Imported, CC907_23090Imported, CC972_05530Imported, D4Z37_00175Imported, D6Q30_23500Imported, DKA88_02860Imported, DNM71_03840Imported, DNV09_05925Imported, DS261_03325Imported, DUQ91_03325Imported, DUV11_02145Imported, DVG36_02675Imported, EBC38_03245Imported, ELQ62_01235Imported, EU445_03250Imported, EVI00_04590Imported, F9R11_04525Imported, F9Y21_04485Imported, FI137_00165Imported, G2227_05670Imported, G2244_03240Imported, G3982_002201Imported, G3V49_004195Imported, G4I71_000797Imported, G4L28_000020Imported, G4P30_000375Imported, G4Y41_004420Imported, G4Y55_001121Imported, G9264_002209Imported, G9C68_000754Imported, G9X37_004360Imported, GDI29_04525Imported, GND71_000648Imported, ZZ17_01385Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmonella typhiImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri90370 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002670 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
220341.16504211

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG3157, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_112762_3_0_6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.30.110.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036624, Hcp1-lik_sf
IPR008514, T6SS_Hcp

Pfam protein domain database

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Pfami
View protein in Pfam
PF05638, T6SS_HCP, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF141452, SSF141452, 1 hit

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR03344, VI_effect_Hcp1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8Z3S0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAIFLKLDN IKGESQVEGF EDQIEIMSYS HNVAMQVNND VSLTERTSGR
60 70 80 90 100
AHVGEMSLTK FVDLATPVLN EYCCSGRLIR TAVLTLCRND DGKMRSLIVY
110 120 130 140 150
TLTNVLISQL SVSGGAGGKP VETMSLNFTK IKWQITAEKS DGAQQESRAS
160
VWDLAMDQIG K
Length:161
Mass (Da):17,723
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEBFBC30DFE354D31
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014613 Genomic DNA Translation: AAO70598.1
AL513382 Genomic DNA Translation: CAD02963.1
AAFJDY010000001 Genomic DNA Translation: EBG5392366.1
AAGUIA010000003 Genomic DNA Translation: EBS0135977.1
AAGULE010000078 Genomic DNA Translation: EBS1101152.1
AAGVVD010000002 Genomic DNA Translation: EBS5362944.1
AAGWES010000001 Genomic DNA Translation: EBS6524409.1
AAHEBT010000003 Genomic DNA Translation: EBV0719474.1
AAHEEH010000007 Genomic DNA Translation: EBV1032270.1
AAHHUX010000003 Genomic DNA Translation: EBW2551559.1
AAHLZU010000003 Genomic DNA Translation: EBX7032589.1
AAHNRO010000003 Genomic DNA Translation: EBY2832658.1
AAHRAJ010000003 Genomic DNA Translation: EBZ4080931.1
AAHUNO010000002 Genomic DNA Translation: ECA4922668.1
AAHWPO010000003 Genomic DNA Translation: ECB1383627.1
AAHWWI010000003 Genomic DNA Translation: ECB2192079.1
AAKUKE010000002 Genomic DNA Translation: ECV8214434.1
AALNBT010000003 Genomic DNA Translation: EDB3134872.1
AALNGB010000003 Genomic DNA Translation: EDB3625489.1
AAMFQS010000004 Genomic DNA Translation: EDG8856180.1
AAMFQZ010000003 Genomic DNA Translation: EDG8891383.1
AAMFRD010000079 Genomic DNA Translation: EDG8904243.1
AAMFRJ010000118 Genomic DNA Translation: EDG8935371.1
AAMHNJ010000003 Genomic DNA Translation: EDH3994375.1
AAMICL010000003 Genomic DNA Translation: EDH5799696.1
AAMJUX010000003 Genomic DNA Translation: EDI0956752.1
AAMJVG010000073 Genomic DNA Translation: EDI0996422.1
AAMJWL010000004 Genomic DNA Translation: EDI1138168.1
DAAQQG010000003 Genomic DNA Translation: HAE0415673.1
DAAQQU010000004 Genomic DNA Translation: HAE0480393.1
DAARDQ010000083 Genomic DNA Translation: HAE1999072.1
DAARRK010000019 Genomic DNA Translation: HAE3628592.1
DAASLV010000006 Genomic DNA Translation: HAE6053650.1
DAASSY010000001 Genomic DNA Translation: HAE6905544.1
DAASYX010000002 Genomic DNA Translation: HAE7597107.1
DAATAS010000003 Genomic DNA Translation: HAE7808913.1
DAATOU010000126 Genomic DNA Translation: HAE9017627.1
DAATPQ010000004 Genomic DNA Translation: HAE9578413.1
DAATYW010000003 Genomic DNA Translation: HAF0685285.1
DAAWCE010000157 Genomic DNA Translation: HAF7363645.1
DAAWDS010000020 Genomic DNA Translation: HAF7398739.1

NCBI Reference Sequences

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RefSeqi
NP_457526.1, NC_003198.1
WP_000338756.1, NZ_WSUR01000003.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO70598; AAO70598; t3052
CAD02963; CAD02963; CAD02963
CGV21502; CGV21502; ERS248933_00240

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
stt:t3052
sty:STY3300

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|220341.7.peg.3361

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014613 Genomic DNA Translation: AAO70598.1
AL513382 Genomic DNA Translation: CAD02963.1
AAFJDY010000001 Genomic DNA Translation: EBG5392366.1
AAGUIA010000003 Genomic DNA Translation: EBS0135977.1
AAGULE010000078 Genomic DNA Translation: EBS1101152.1
AAGVVD010000002 Genomic DNA Translation: EBS5362944.1
AAGWES010000001 Genomic DNA Translation: EBS6524409.1
AAHEBT010000003 Genomic DNA Translation: EBV0719474.1
AAHEEH010000007 Genomic DNA Translation: EBV1032270.1
AAHHUX010000003 Genomic DNA Translation: EBW2551559.1
AAHLZU010000003 Genomic DNA Translation: EBX7032589.1
AAHNRO010000003 Genomic DNA Translation: EBY2832658.1
AAHRAJ010000003 Genomic DNA Translation: EBZ4080931.1
AAHUNO010000002 Genomic DNA Translation: ECA4922668.1
AAHWPO010000003 Genomic DNA Translation: ECB1383627.1
AAHWWI010000003 Genomic DNA Translation: ECB2192079.1
AAKUKE010000002 Genomic DNA Translation: ECV8214434.1
AALNBT010000003 Genomic DNA Translation: EDB3134872.1
AALNGB010000003 Genomic DNA Translation: EDB3625489.1
AAMFQS010000004 Genomic DNA Translation: EDG8856180.1
AAMFQZ010000003 Genomic DNA Translation: EDG8891383.1
AAMFRD010000079 Genomic DNA Translation: EDG8904243.1
AAMFRJ010000118 Genomic DNA Translation: EDG8935371.1
AAMHNJ010000003 Genomic DNA Translation: EDH3994375.1
AAMICL010000003 Genomic DNA Translation: EDH5799696.1
AAMJUX010000003 Genomic DNA Translation: EDI0956752.1
AAMJVG010000073 Genomic DNA Translation: EDI0996422.1
AAMJWL010000004 Genomic DNA Translation: EDI1138168.1
DAAQQG010000003 Genomic DNA Translation: HAE0415673.1
DAAQQU010000004 Genomic DNA Translation: HAE0480393.1
DAARDQ010000083 Genomic DNA Translation: HAE1999072.1
DAARRK010000019 Genomic DNA Translation: HAE3628592.1
DAASLV010000006 Genomic DNA Translation: HAE6053650.1
DAASSY010000001 Genomic DNA Translation: HAE6905544.1
DAASYX010000002 Genomic DNA Translation: HAE7597107.1
DAATAS010000003 Genomic DNA Translation: HAE7808913.1
DAATOU010000126 Genomic DNA Translation: HAE9017627.1
DAATPQ010000004 Genomic DNA Translation: HAE9578413.1
DAATYW010000003 Genomic DNA Translation: HAF0685285.1
DAAWCE010000157 Genomic DNA Translation: HAF7363645.1
DAAWDS010000020 Genomic DNA Translation: HAF7398739.1
RefSeqiNP_457526.1, NC_003198.1
WP_000338756.1, NZ_WSUR01000003.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi220341.16504211

Genome annotation databases

EnsemblBacteriaiAAO70598; AAO70598; t3052
CAD02963; CAD02963; CAD02963
CGV21502; CGV21502; ERS248933_00240
KEGGistt:t3052
sty:STY3300
PATRICifig|220341.7.peg.3361

Phylogenomic databases

eggNOGiCOG3157, Bacteria
HOGENOMiCLU_112762_3_0_6

Family and domain databases

Gene3Di2.30.110.20, 1 hit
InterProiView protein in InterPro
IPR036624, Hcp1-lik_sf
IPR008514, T6SS_Hcp
PfamiView protein in Pfam
PF05638, T6SS_HCP, 1 hit
SUPFAMiSSF141452, SSF141452, 1 hit
TIGRFAMsiTIGR03344, VI_effect_Hcp1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8Z3S0_SALTI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8Z3S0
Secondary accession number(s): A0A0C8SRY2, Q7C785
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 10, 2021
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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