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Entry version 113 (11 Dec 2019)
Sequence version 1 (01 Mar 2002)
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Protein

Glycogen debranching enzyme

Gene

glgX

Organism
Salmonella typhi
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Hydrolysis of (1->6)-alpha-D-glucosidic linkages to branches with degrees of polymerization of three or four glucose residues in limit dextrin.UniRule annotation EC:3.2.1.196

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: glycogen degradation

This protein is involved in the pathway glycogen degradation, which is part of Glycan degradation.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei336NucleophileUniRule annotation1
Active sitei371Proton donorUniRule annotation1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei443Transition state stabilizerUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Glycogen metabolism

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
GCF_001048035:AC754_RS01590-MONOMER
GCF_001048375:AC768_RS01585-MONOMER
GCF_001079465:ADV44_RS21940-MONOMER
GCF_001088345:AEZ18_RS02845-MONOMER
GCF_001095585:AD238_RS01965-MONOMER
GCF_001104165:AE704_RS01590-MONOMER
GCF_001104885:AEZ38_RS01580-MONOMER
GCF_001106745:AE121_RS21960-MONOMER
GCF_001118185:AE086_RS01590-MONOMER
GCF_001119245:AE140_RS01585-MONOMER
GCF_001121865:AE338_RS01590-MONOMER
GCF_001127485:AE735_RS01585-MONOMER
GCF_001135805:AEG73_RS01590-MONOMER
GCF_001148125:AEN24_RS21460-MONOMER
GCF_001148305:AEN67_RS02830-MONOMER
GCF_001157245:AER93_RS01800-MONOMER
GCF_001163025:AFA50_RS01585-MONOMER
GCF_001165785:AFA97_RS01590-MONOMER
GCF_001240865:ALC23_RS02855-MONOMER
GCF_001356455:AQJ76_RS01585-MONOMER
GCF_001357935:AQL34_RS11550-MONOMER
GCF_001359015:AQL50_RS11245-MONOMER
GCF_001360555:AQK88_RS01585-MONOMER
GCF_001361075:AQM75_RS22700-MONOMER
GCF_001362095:AQO19_RS01595-MONOMER
GCF_001362135:AQN73_RS02735-MONOMER
GCF_001362175:AQN68_RS01585-MONOMER
GCF_001362195:AQN87_RS14335-MONOMER
GCF_001362335:AQN99_RS02835-MONOMER
GCF_001364695:AQQ97_RS11870-MONOMER
GCF_900185485:CDZ80_RS22345-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00165

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glycogen debranching enzymeUniRule annotation (EC:3.2.1.196UniRule annotation)
Alternative name(s):
Limit dextrin alpha-1,6-maltotetraose-hydrolaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:glgXUniRule annotation
Ordered Locus Names:STY4273, t3983
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmonella typhi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri90370 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002670 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000543011 – 654Glycogen debranching enzymeAdd BLAST654

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
220341.16505070

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8Z234

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4108ESZ Bacteria
COG1523 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000239197

KEGG Orthology (KO)

More...
KOi
K02438

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
2.60.40.1180, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01248 GlgX, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040784 GlgX_C
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR022844 Glycogen_debranch_bac
IPR011837 Glycogen_debranch_GlgX
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02922 CBM_48, 1 hit
PF18390 GlgX_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00642 Aamy, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02100 glgX_debranch, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8Z234-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTQLAIGEAT PHGATYDGHG VNFTLFSAHA ERVELCVFDS RGNERRYDLP
60 70 80 90 100
GRRGDVWHGY LAGARPGLRY GYRVHGPWQP AQGHRFNPAK LLLDPYARQV
110 120 130 140 150
EGELKDHPLL HGGHDEPDYR DNAAVAPKSV VISDHYDWED DAAPRTPWGK
160 170 180 190 200
TVIYEAHVKG LTYLHPELPQ EIRGTYKALG HPVMVAYFKQ LGITALELLP
210 220 230 240 250
VAQFASEPRL QRMGLTNYWG YNPMAMFALH PAWASSPETA LDEFRDAVKA
260 270 280 290 300
LHRAGIEVIL DIVLNHSAEL DLDGPTFSLR GIDNRSYYWI RDDGDYHNWT
310 320 330 340 350
GCGNTLNLSH PGVVEYACEC LRYWMETCHV DGFRFDLASV MGRTPTFRQD
360 370 380 390 400
APLFAAIKAC PVLSTVKLIA EPWDIGEGGY QVGNFPPPFA EWNDHFRDAA
410 420 430 440 450
RRFWLPRNLT TGEFACRFAA SSDVFKRNGR APGASVNLLT AHDGFTLRDC
460 470 480 490 500
VCFNQKHNEA NGEENRDGTN SNYSDNHGKE GLGGPLDLME RRRDSIHALL
510 520 530 540 550
ATLLLSQGTP MLLAGDEHGH SQHGNNNAYC QDNALTWLDW QQANRGLTTF
560 570 580 590 600
TAALIRLRQQ IPALTGNSWW EEGDGNVRWL NKNAQPLSAD EWQNGPKLMQ
610 620 630 640 650
ILLSDRFLIA INATLEVTDI VLPEGEWRAV PPFAGEDNPV ITAVWQGLCV

FQRG
Length:654
Mass (Da):73,253
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BB035D2725910CE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD08091.1
AE014613 Genomic DNA Translation: AAO71453.1

NCBI Reference Sequences

More...
RefSeqi
NP_458381.1, NC_003198.1
WP_000192475.1, NZ_UFRG01000003.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO71453; AAO71453; t3983
CAD08091; CAD08091; CAD08091

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1250490

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
stt:t3983
sty:STY4273

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|220341.7.peg.4366

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD08091.1
AE014613 Genomic DNA Translation: AAO71453.1
RefSeqiNP_458381.1, NC_003198.1
WP_000192475.1, NZ_UFRG01000003.1

3D structure databases

SMRiQ8Z234
ModBaseiSearch...

Protein-protein interaction databases

STRINGi220341.16505070

Genome annotation databases

EnsemblBacteriaiAAO71453; AAO71453; t3983
CAD08091; CAD08091; CAD08091
GeneIDi1250490
KEGGistt:t3983
sty:STY4273
PATRICifig|220341.7.peg.4366

Phylogenomic databases

eggNOGiENOG4108ESZ Bacteria
COG1523 LUCA
HOGENOMiHOG000239197
KOiK02438

Enzyme and pathway databases

UniPathwayiUPA00165
BioCyciGCF_001048035:AC754_RS01590-MONOMER
GCF_001048375:AC768_RS01585-MONOMER
GCF_001079465:ADV44_RS21940-MONOMER
GCF_001088345:AEZ18_RS02845-MONOMER
GCF_001095585:AD238_RS01965-MONOMER
GCF_001104165:AE704_RS01590-MONOMER
GCF_001104885:AEZ38_RS01580-MONOMER
GCF_001106745:AE121_RS21960-MONOMER
GCF_001118185:AE086_RS01590-MONOMER
GCF_001119245:AE140_RS01585-MONOMER
GCF_001121865:AE338_RS01590-MONOMER
GCF_001127485:AE735_RS01585-MONOMER
GCF_001135805:AEG73_RS01590-MONOMER
GCF_001148125:AEN24_RS21460-MONOMER
GCF_001148305:AEN67_RS02830-MONOMER
GCF_001157245:AER93_RS01800-MONOMER
GCF_001163025:AFA50_RS01585-MONOMER
GCF_001165785:AFA97_RS01590-MONOMER
GCF_001240865:ALC23_RS02855-MONOMER
GCF_001356455:AQJ76_RS01585-MONOMER
GCF_001357935:AQL34_RS11550-MONOMER
GCF_001359015:AQL50_RS11245-MONOMER
GCF_001360555:AQK88_RS01585-MONOMER
GCF_001361075:AQM75_RS22700-MONOMER
GCF_001362095:AQO19_RS01595-MONOMER
GCF_001362135:AQN73_RS02735-MONOMER
GCF_001362175:AQN68_RS01585-MONOMER
GCF_001362195:AQN87_RS14335-MONOMER
GCF_001362335:AQN99_RS02835-MONOMER
GCF_001364695:AQQ97_RS11870-MONOMER
GCF_900185485:CDZ80_RS22345-MONOMER

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_01248 GlgX, 1 hit
InterProiView protein in InterPro
IPR040784 GlgX_C
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR022844 Glycogen_debranch_bac
IPR011837 Glycogen_debranch_GlgX
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02922 CBM_48, 1 hit
PF18390 GlgX_C, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR02100 glgX_debranch, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGLGX_SALTI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8Z234
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: March 1, 2002
Last modified: December 11, 2019
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
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