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Entry version 105 (03 Jul 2019)
Sequence version 1 (11 Feb 2002)
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Protein

Uncharacterized WD repeat-containing protein alr2800

Gene

alr2800

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized WD repeat-containing protein alr2800
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:alr2800
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri103690 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002483 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000515141 – 1258Uncharacterized WD repeat-containing protein alr2800Add BLAST1258

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8YTC2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
103690.17131893

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8YTC2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati55 – 93WD 1Add BLAST39
Repeati640 – 679WD 2Add BLAST40
Repeati682 – 721WD 3Add BLAST40
Repeati724 – 763WD 4Add BLAST40
Repeati766 – 807WD 5Add BLAST42
Repeati809 – 849WD 6Add BLAST41
Repeati850 – 889WD 7Add BLAST40
Repeati892 – 931WD 8Add BLAST40
Repeati934 – 975WD 9Add BLAST42
Repeati976 – 1017WD 10Add BLAST42
Repeati1019 – 1059WD 11Add BLAST41
Repeati1060 – 1101WD 12Add BLAST42
Repeati1103 – 1143WD 13Add BLAST41
Repeati1144 – 1183WD 14Add BLAST40
Repeati1186 – 1227WD 15Add BLAST42

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CNF Bacteria
ENOG410XP3K LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000023052

Identification of Orthologs from Complete Genome Data

More...
OMAi
ATCDTDC

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00093 HTH_XRE, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 7 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001387 Cro/C1-type_HTH
IPR020472 G-protein_beta_WD-40_rep
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00931 NB-ARC, 1 hit
PF00400 WD40, 14 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00320 GPROTEINBRPT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 14 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 2 hits
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00678 WD_REPEATS_1, 9 hits
PS50082 WD_REPEATS_2, 14 hits
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8YTC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILQSTSLFC KYINNCRYIN REIVATLKAS PQGLARIKQA RSDRGWSVDD
60 70 80 90 100
FRWLELASEI LGVCWQENGV LAAGISEGTW KRFLAGKQAI NAEAFKAYCQ
110 120 130 140 150
VLGLNWEEVQ EGGRTKERKD TGTSRQEKFL SSSHPHTDWG EAPDVSIFYG
160 170 180 190 200
RSEELDTVKR WVTQENCRLI TLLGMGGIGK TTLSVKLAQE IINSEKIYLS
210 220 230 240 250
QSPEYIIWRS LRNAPPVEDI LAELIQFLSG QQETNLSNHL QGRISLLLKN
260 270 280 290 300
LRSSRCLIIL DNAESILQAG DRNGRYRAGC EGYGQFLQCI AETSHQSCLI
310 320 330 340 350
LTSREKPQGL AKYEGDSLPV RSLPLTGLQE QEGRELFNVK GKFAASCDQW
360 370 380 390 400
QVLISRYGGN PLALKIVASS IRDFFDGDVS QFLEVSQQGT FIFDDIRDLL
410 420 430 440 450
DQQFQRLTTL EREIMYWLAI NREPVTLAEL QADFVANIPP RELLESLSSL
460 470 480 490 500
QRRSLIEKSA GGFTQQPVVM EYVSNHLIEQ VCEEMREWGL VRSRGAEEQR
510 520 530 540 550
SRGEKIHTQY KLNAALPLTA LSTPLFTTHA LIKAQAKDYV RESQISLILQ
560 570 580 590 600
PLINQLITEF GSLENISNCL VHILSRLRGK SPQETGYAGG NVLNLLHHAQ
610 620 630 640 650
VDLSGYDFSG LTVWQAYLQG VNLHDVDFAN SDLSCCVFTE TLGNILSAAF
660 670 680 690 700
SPEGQLLATC DTDCHVRVWE VKSGKLLLIC RGHSNWVRFV VFSPDGEILA
710 720 730 740 750
SCGADENVKL WSVRDGVCIK TLTGHEHEVF SVAFHPDGET LASASGDKTI
760 770 780 790 800
KLWDIQDGTC LQTLTGHTDW VRCVAFSPDG NTLASSAADH TIKLWDVSQG
810 820 830 840 850
KCLRTLKSHT GWVRSVAFSA DGQTLASGSG DRTIKIWNYH TGECLKTYIG
860 870 880 890 900
HTNSVYSIAY SPDSKILVSG SGDRTIKLWD CQTHICIKTL HGHTNEVCSV
910 920 930 940 950
AFSPDGQTLA CVSLDQSVRL WNCRTGQCLK AWYGNTDWAL PVAFSPDRQI
960 970 980 990 1000
LASGSNDKTV KLWDWQTGKY ISSLEGHTDF IYGIAFSPDS QTLASASTDS
1010 1020 1030 1040 1050
SVRLWNISTG QCFQILLEHT DWVYAVVFHP QGKIIATGSA DCTVKLWNIS
1060 1070 1080 1090 1100
TGQCLKTLSE HSDKILGMAW SPDGQLLASA SADQSVRLWD CCTGRCVGIL
1110 1120 1130 1140 1150
RGHSNRVYSA IFSPNGEIIA TCSTDQTVKI WDWQQGKCLK TLTGHTNWVF
1160 1170 1180 1190 1200
DIAFSPDGKI LASASHDQTV RIWDVNTGKC HHICIGHTHL VSSVAFSPDG
1210 1220 1230 1240 1250
EVVASGSQDQ TVRIWNVKTG ECLQILRAKR LYEGMNITGV TGLTKATIFT

LQALGALR
Length:1,258
Mass (Da):139,514
Last modified:February 11, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i45DF03B91170C451
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BA000019 Genomic DNA Translation: BAB74499.1

Protein sequence database of the Protein Information Resource

More...
PIRi
AI2155

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAB74499; BAB74499; BAB74499

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ana:alr2800

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA Translation: BAB74499.1
PIRiAI2155

3D structure databases

SMRiQ8YTC2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi103690.17131893

Proteomic databases

PRIDEiQ8YTC2

Genome annotation databases

EnsemblBacteriaiBAB74499; BAB74499; BAB74499
KEGGiana:alr2800

Phylogenomic databases

eggNOGiENOG4105CNF Bacteria
ENOG410XP3K LUCA
HOGENOMiHOG000023052
OMAiATCDTDC

Family and domain databases

CDDicd00093 HTH_XRE, 1 hit
Gene3Di2.130.10.10, 7 hits
InterProiView protein in InterPro
IPR001387 Cro/C1-type_HTH
IPR020472 G-protein_beta_WD-40_rep
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00931 NB-ARC, 1 hit
PF00400 WD40, 14 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 14 hits
SUPFAMiSSF50978 SSF50978, 2 hits
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 9 hits
PS50082 WD_REPEATS_2, 14 hits
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY2800_NOSS1
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8YTC2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: February 11, 2002
Last modified: July 3, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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