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Entry version 107 (12 Aug 2020)
Sequence version 1 (01 Mar 2002)
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Protein

Uncharacterized WD repeat-containing protein alr3466

Gene

alr3466

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized WD repeat-containing protein alr3466
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:alr3466
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri103690 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002483 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000515151 – 1526Uncharacterized WD repeat-containing protein alr3466Add BLAST1526

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8YRI1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
103690.17132599

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8YRI1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati334 – 376WD 1Add BLAST43
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini823 – 862Pentapeptide repeatAdd BLAST40
Repeati862 – 901WD 2Add BLAST40
Repeati904 – 945WD 3Add BLAST42
Repeati946 – 985WD 4Add BLAST40
Repeati988 – 1027WD 5Add BLAST40
Repeati1030 – 1069WD 6Add BLAST40
Repeati1072 – 1111WD 7Add BLAST40
Repeati1114 – 1153WD 8Add BLAST40
Repeati1156 – 1195WD 9Add BLAST40
Repeati1198 – 1237WD 10Add BLAST40
Repeati1240 – 1279WD 11Add BLAST40
Repeati1282 – 1321WD 12Add BLAST40
Repeati1324 – 1363WD 13Add BLAST40
Repeati1366 – 1405WD 14Add BLAST40
Repeati1408 – 1447WD 15Add BLAST40
Repeati1450 – 1491WD 16Add BLAST42

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG2319, Bacteria
COG5635, Bacteria

Identification of Orthologs from Complete Genome Data

More...
OMAi
TGDCVQT

Database of Orthologous Groups

More...
OrthoDBi
1377603at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 8 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001646, 5peptide_repeat
IPR020472, G-protein_beta_WD-40_rep
IPR007111, NACHT_NTPase
IPR027417, P-loop_NTPase
IPR011047, Quinoprotein_ADH-like_supfam
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05729, NACHT, 1 hit
PF00805, Pentapeptide, 1 hit
PF00400, WD40, 15 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00320, GPROTEINBRPT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 2 hits
SSF50998, SSF50998, 1 hit
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50837, NACHT, 1 hit
PS00678, WD_REPEATS_1, 11 hits
PS50082, WD_REPEATS_2, 15 hits
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8YRI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSLINLDLV ISAVTSIANP VIKEKILRSE TVIKLLQQFN LDPEHPPADF
60 70 80 90 100
SGVYAYTLVE YGVGKPKAFL ELFRQEAIKQ AFRKALDHNN PSILLSEVDT
110 120 130 140 150
FLDACTLGDE IRSLELDVRR EVAAFATVFI EVAKRSRTPA DVLMNQQIGS
160 170 180 190 200
LHKRIAGIQE QLERLPTLEG IRTEIARLAA QNYPALTPTA TENQCRAIAL
210 220 230 240 250
AQQMRGWFET LGYRLEKYEI WAEEYFEWII NVPVRRSYDR ILVRGVAGEV
260 270 280 290 300
RLSDVMALCQ SVNQQKTDEG WLVSTRRISR AARDEVKKEE NRHLDCFTFD
310 320 330 340 350
ELIDLDADFS GYLDWLEAEI KRRKIDQKYV PLACTKEEID PVTKRRIGIS
360 370 380 390 400
RYEAEDGWID GYIDLWLDDP AKEHISILGE FGTGKTWFVF HYAWTALQRY
410 420 430 440 450
KDAQRRGVER PRLPLVITLR DFAKALNVEN VLAGFFFTQH NIRLNSEVFD
460 470 480 490 500
QLNRMGKLLL IFDGFDEMAA KVDRQQMINN FWELAKVVVP GSKVILTCRT
510 520 530 540 550
EHFPEAKEGR ALLNAELQAS TNKLTGETPQ FEVLELEKFN DEQIRQVLLY
560 570 580 590 600
QAEEATVEQI MGNSQLLDLA RRPVMTDLIL EALPDIEAGK PIDMSRVYLY
610 620 630 640 650
AVRHKMERDI KAERTFNSLA DKLYFLCELS WEMLSTDQMS LNYRLFPERI
660 670 680 690 700
RRLFGSVVQE EKDLDHWHYD MMAQTMLVRN ADGDYTPAHR SLLEFFVAYK
710 720 730 740 750
FAAELGALAR DFTEVGQAQS GLDSSTASID YTWSGYFSRQ LDSTGCREVI
760 770 780 790 800
APLRQFKSEF LDKLRETFGK AKLTKAVIDL LLPMLDDNEP LIKIIEATRG
810 820 830 840 850
RTEDEVNYVG GNAATLLVKL NKMVLEGRDL SHTVIIGADF TNTSLRCVNF
860 870 880 890 900
TEANLAYSVF TKILGSVLTV AFSPDGKLFA TGDSGGIVRF WEAATGKELL
910 920 930 940 950
TCKGHNSWVN SVGFSQDGKM LASGSDDQTV RLWDISSGQC LKTFKGHTSR
960 970 980 990 1000
VRSVVFSPNS LMLASGSSDQ TVRLWDISSG ECLYIFQGHT GWVYSVAFNL
1010 1020 1030 1040 1050
DGSMLATGSG DQTVRLWDIS SSQCFYIFQG HTSCVRSVVF SSDGAMLASG
1060 1070 1080 1090 1100
SDDQTVRLWD ISSGNCLYTL QGHTSCVRSV VFSPDGAMLA SGGDDQIVRL
1110 1120 1130 1140 1150
WDISSGNCLY TLQGYTSWVR FLVFSPNGVT LANGSSDQIV RLWDISSKKC
1160 1170 1180 1190 1200
LYTLQGHTNW VNAVAFSPDG ATLASGSGDQ TVRLWDISSS KCLYILQGHT
1210 1220 1230 1240 1250
SWVNSVVFNP DGSTLASGSS DQTVRLWEIN SSKCLCTFQG HTSWVNSVVF
1260 1270 1280 1290 1300
NPDGSMLASG SSDKTVRLWD ISSSKCLHTF QGHTNWVNSV AFNPDGSMLA
1310 1320 1330 1340 1350
SGSGDQTVRL WEISSSKCLH TFQGHTSWVS SVTFSPDGTM LASGSDDQTV
1360 1370 1380 1390 1400
RLWSISSGEC LYTFLGHTNW VGSVIFSPDG AILASGSGDQ TVRLWSISSG
1410 1420 1430 1440 1450
KCLYTLQGHN NWVGSIVFSP DGTLLASGSD DQTVRLWNIS SGECLYTLHG
1460 1470 1480 1490 1500
HINSVRSVAF SSDGLILASG SDDETIKLWD VKTGECIKTL KSEKIYEGMN
1510 1520
ITSVRGLTEV EKATLKTLGA VENREI
Length:1,526
Mass (Da):170,377
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD5DF272509B4A738
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BA000019 Genomic DNA Translation: BAB75165.1

Protein sequence database of the Protein Information Resource

More...
PIRi
AC2239

NCBI Reference Sequences

More...
RefSeqi
WP_010997616.1, NZ_RSCN01000015.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAB75165; BAB75165; BAB75165

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ana:alr3466

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA Translation: BAB75165.1
PIRiAC2239
RefSeqiWP_010997616.1, NZ_RSCN01000015.1

3D structure databases

SMRiQ8YRI1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi103690.17132599

Proteomic databases

PRIDEiQ8YRI1

Genome annotation databases

EnsemblBacteriaiBAB75165; BAB75165; BAB75165
KEGGiana:alr3466

Phylogenomic databases

eggNOGiCOG2319, Bacteria
COG5635, Bacteria
OMAiTGDCVQT
OrthoDBi1377603at2

Family and domain databases

Gene3Di2.130.10.10, 8 hits
InterProiView protein in InterPro
IPR001646, 5peptide_repeat
IPR020472, G-protein_beta_WD-40_rep
IPR007111, NACHT_NTPase
IPR027417, P-loop_NTPase
IPR011047, Quinoprotein_ADH-like_supfam
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF05729, NACHT, 1 hit
PF00805, Pentapeptide, 1 hit
PF00400, WD40, 15 hits
PRINTSiPR00320, GPROTEINBRPT
SMARTiView protein in SMART
SM00320, WD40, 15 hits
SUPFAMiSSF50978, SSF50978, 2 hits
SSF50998, SSF50998, 1 hit
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50837, NACHT, 1 hit
PS00678, WD_REPEATS_1, 11 hits
PS50082, WD_REPEATS_2, 15 hits
PS50294, WD_REPEATS_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYY46_NOSS1
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8YRI1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: March 1, 2002
Last modified: August 12, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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