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Protein

Probable transaldolase

Gene

tal

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciBMEL224914:G1FZL-257-MONOMER
UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:BMEI0244
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001736601 – 217Probable transaldolaseAdd BLAST217

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_2920

Structurei

3D structure databases

ProteinModelPortaliQ8YJ42
SMRiQ8YJ42
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000226073
KOiK00616
OMAiVRHPMHV

Family and domain databases

CDDicd00956 Transaldolase_FSA, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00494 Transaldolase_3b, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR022999 Transaldolase_3B
IPR004731 Transaldolase_3B/F6P_aldolase
IPR018225 Transaldolase_AS
IPR033919 TSA/FSA_arc/bac
PANTHERiPTHR10683 PTHR10683, 2 hits
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00875 fsa_talC_mipB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8YJ42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFFVDTADV KEIRELNDLG LVDGVTTNPS LILKSGRDII EVTKEICNIV
60 70 80 90 100
KGPVSAEVAA TEYEQMMKEA AVIARIADNI CIKLPVTLDG LKACKALTSE
110 120 130 140 150
GHKVNMTLCF SANQALLAAK AGATFISPFI GRLDDTGING MELIAEIRTI
160 170 180 190 200
YDNYDFRTEI LAASVRTVNH VKEAALIGAD VVTAPPATLK ALVKHPLTYK
210
GLETFLADWA KTGQKIA
Length:217
Mass (Da):23,407
Last modified:March 1, 2002 - v1
Checksum:i69E2119EDE74CA52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51426.1
PIRiAG3282
RefSeqiWP_004684273.1, NZ_GG703781.1

Genome annotation databases

EnsemblBacteriaiAAL51426; AAL51426; BMEI0244
GeneIDi29593007
KEGGibme:BMEI0244
bmel:DK63_1187
PATRICifig|224914.52.peg.1254

Similar proteinsi

Entry informationi

Entry nameiTAL_BRUME
AccessioniPrimary (citable) accession number: Q8YJ42
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2002
Last modified: February 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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