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Protein

Elongation factor P

Gene

efp

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Pathwayi: polypeptide chain elongation

This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

UniPathwayi
UPA00345

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotation
Ordered Locus Names:BMEI0327
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000942131 – 186Elongation factor PAdd BLAST186

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_3002

Structurei

3D structure databases

ProteinModelPortaliQ8YIW2
SMRiQ8YIW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRH Bacteria
COG0231 LUCA
HOGENOMiHOG000010048
KOiK02356
OMAiNTFSAGH

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR013852 Transl_elong_P/YeiP_CS
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit
PROSITEiView protein in PROSITE
PS01275 EFP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8YIW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKINGNEIRP GNVIEHEGGL WVAVKTNAVK PGKGGAYNQV ELKNLINGTK
60 70 80 90 100
LNERFRAAES VERVRLEQKD FSFLYEQGEA LIFMDTETYE QLELQKDFVG
110 120 130 140 150
DRAAFLQDGM MVTVELYEEK PIGIRLPDQV TLAITEADPV VKGQTAASSY
160 170 180
KPAVLENGIR IPVPPFIASG ERVIVDTNEL TYISRA
Length:186
Mass (Da):20,700
Last modified:March 1, 2002 - v1
Checksum:i0DB78F78885EC53A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51508.1
PIRiAI3292
RefSeqiWP_002964799.1, NZ_GG703781.1

Genome annotation databases

EnsemblBacteriaiAAL51508; AAL51508; BMEI0327
GeneIDi29593079
KEGGibme:BMEI0327
bmel:DK63_1107
PATRICifig|224914.52.peg.1166

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA Translation: AAL51508.1
PIRiAI3292
RefSeqiWP_002964799.1, NZ_GG703781.1

3D structure databases

ProteinModelPortaliQ8YIW2
SMRiQ8YIW2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_3002

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL51508; AAL51508; BMEI0327
GeneIDi29593079
KEGGibme:BMEI0327
bmel:DK63_1107
PATRICifig|224914.52.peg.1166

Phylogenomic databases

eggNOGiENOG4105DRH Bacteria
COG0231 LUCA
HOGENOMiHOG000010048
KOiK02356
OMAiNTFSAGH

Enzyme and pathway databases

UniPathwayi
UPA00345

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR013852 Transl_elong_P/YeiP_CS
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit
PROSITEiView protein in PROSITE
PS01275 EFP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEFP_BRUME
AccessioniPrimary (citable) accession number: Q8YIW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: March 1, 2002
Last modified: October 10, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
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Main funding by: National Institutes of Health

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